PUBLISHER: DataM Intelligence | PRODUCT CODE: 1373371
PUBLISHER: DataM Intelligence | PRODUCT CODE: 1373371
Bronchiectasis is a chronic condition where the walls of the bronchi are thickened from inflammation and infection. Individuals with bronchiectasis have periodic flare-ups of breathing difficulties called exacerbations.
Symptoms of bronchiectasis include chronic cough with shortness of breath, coughing up blood, and chest pain. The airway blockage like a growth or a noncancerous tumor can also lead to bronchiectasis. Common drugs used in the treatment of bronchiectasis include antibiotics, expectorants, and mucolytics
The increasing prevalence of bronchiectasis acts as a significant driver for market growth. Bronchiectasis often occurs in the presence of chronic obstructive pulmonary disease and is characterized pathologically by permanent bronchial dilatation and severe bronchial inflammation.
For instance, according to a National Institute of Health report published in 2022, Chinese adults had a 2.31-fold increase in the prevalence of bronchiectasis, going from 75.48 (62.26, 88.69) per 100,000 to 174.45 (137.02, 211.88) per 100,000.
Additionally, according to the Royal Australian College of General Practitioners report published in December 2022, states that the estimated prevalence of bronchiectasis is 1470 per 100,000 in Central Australian children.
Furthermore, significant growth drivers such as the rising incidence of pulmonary diseases, the growing geriatric population, and increasing clinical trials, are expected to drive the market in the forecast period.
The lack of approved drugs for bronchiectasis, stringent regulatory policies, high costs involved in research and development under-diagnosis of bronchiectasis, and preference for substitute treatment options are some factors hampering the growth of the bronchiectasis treatment market over the forecast period.
The global bronchiectasis drugs market is segmented based on disease type, drug type, route of administration, distribution channel, and region.
Antibiotics are expected to hold the largest market share over the period forecast owing to increasing clinical trials conducted for bronchiectasis with antibiotics. A total of 314 clinical trials were performed till 2023 for the treatment of bronchiectasis with antibiotics.
For instance, according to clinicalTrials.gov, on September 7, 2023, Belfast Health and Social Care Trust in collaboration with Queen's University started a clinical trial of Hypertonic Saline and Carbocisteine in Bronchiectasis. It is currently in phase 3 and the estimated study completion date is September 2024.
Additionally, on September 21, 2023, Insmed Incorporated conducted a clinical trial on the efficacy, safety, and tolerability of Brensocatib in participants with non-cystic fibrosis bronchiectasis. It is currently in phase 3 and the estimated study completion date is March 2024.
The global bronchiectasis drugs market is segmented into North America, Europe, Asia Pacific, South America, Middle East, and Africa.
North America has maintained a significant market proportion due to factors such as the rising prevalence of bronchiectasis infections and drug approvals, this trend is anticipated to continue throughout the forecast period.
For instance, according to the American Lung Association report published in 2022, The risk of developing bronchiectasis increases with age, and Bronchiectasis affects 350,000 to 500,000 people in the United States. The incidence of bronchiectasis is more common in women than in men.
Additionally, in April 2022, Zambon received a U.S FDA Breakthrough Therapy Designation for colistimethate sodium powder for nebulization solution for the reduction in the incidence of pulmonary exacerbations in adult patients with non-cystic fibrosis bronchiectasis (NCFB).
The COVID-19 pandemic has had a significant impact on the global bronchiectasis drugs market. The pandemic disrupted the conduct of clinical trials, with many sites temporarily halting enrollment or modifying protocols to prioritize patient safety. This has led to delays in the completion of trials and the availability of new treatment drugs. Therefore, the bronchiectasis drugs market is expected to be moderately affected over the forecast period.
The major global players in the market include: Zambon S.p.A., Pfizer Inc., Merck KGaA, Soigner Pharma Pvt Ltd, Teva Pharmaceuticals, LGM Pharma LLC, Texas Pharmaceuticals Pvt. Ltd., Orion Life Science, Cepham Life Sciences Inc., AdvaCare Pharma among others.
The global bronchiectasis drugs market report would provide approximately 69 tables, 67 figures, and 185 Pages.