PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1532846
PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1532846
Cell-free Protein Expression Market size was valued at USD 255.6 Million in 2023, expanding at a CAGR of 7.2% from 2024 to 2032.
Protein expression is the process by which proteins are produced, changed, and managed in living organisms. Cell-free protein expression is an in-vitro procedure that uses transaction and compatible extraction of entire cells. It enables the manufacture of the desired protein without the usage of live cells. Researchers use cell-free protein expression to produce and express tiny quantities of functional proteins rapidly.
Cell-free Protein Expression Market- Market Dynamics
Rapid expansion of the pharmaceutical industry
Cell-free protein synthesis (CFPS) technologies have progressed from lab-scale research tools to biopharmaceutical manufacturing on a large scale by good manufacturing procedures (GMPs). CFPS-based products are currently undergoing many human clinical trials. Furthermore, CFPS research applications have advanced greatly over time and are now critical for the discovery and development of new biopharmaceutical drugs.
The peculiar and open nature of CFPS has enabled non-natural amino acids (nnAA) to be effectively integrated into protein products, extending the pool of biotherapeutics that can be considered for new treatments. As the pharmaceutical industry increases in the future years, as does the demand for novel therapies, the market for cell-free protein expression is expected to grow.
Cell-free Protein Expression Market- Key Insights
As per the analysis shared by our research analyst, the global market is estimated to grow annually at a CAGR of around 7.2% over the forecast period (2024-2032)
Based on Product segmentation, Expression Systems was predicted to show maximum market share in the year 2023
Based on application segmentation, enzyme engineering was the leading type in 2023
Based on Method segmentation, transcription & translation were the highest revenue share of the market
Based on region, North America was the leading revenue generator in 2023
The Global Cell-free Protein Expression Market is segmented based on Product, Application, Method, End-User, and Region.
The market is divided into two categories based on Product: Expression Systems and Reagents. The expression systems category accounted for the largest market share in 2023. E. coli lysates are one of the most popular commercial lysates due to their low cost and excellent protein production. Furthermore, E. coli-based systems in recombinant technology are employed for a variety of biological treatments, including insulin.
The market is divided into five categories based on application: Enzyme Engineering, High Throughput Production, Protein Labeling, Protein-Protein Interaction and Protein Purification. The enzyme engineering category dominated the market in 2023. With the advancement of enzyme engineering, it has become increasingly significant in biomanufacturing, synthetic biology, and medicine. Recently, cell-free synthetic biology approaches to enzyme engineering have been explored as an alternate strategy. This approach places no constraints on the cell membrane and does not require cell viability, and each of the biochemical routes is very adaptable.
Cell-free Protein Expression Market- Geographical Insights
Geographically, this market is widespread in the regions of North America, Latin America, Europe, Asia Pacific, and the Middle East and Africa. These regions are further divided as per the nations bringing business. North America led the market in 2023. The considerable number of pharmaceutical businesses and research institutions present in countries, particularly the United States, has contributed to the region's market growth. The availability of venture money, government grants, and funding organizations for biotechnology research and development in North America has been critical to the expansion of the cell-free protein expression sector.
Asia Pacific is predicted to experience the quickest rate of growth over the forecast period. Collaborations between local and international biotech companies and academic institutions have facilitated knowledge transfer and technological acceptance, helping to build the cell-free protein expression market. Asia Pacific has a highly educated and talented workforce in biotechnology and molecular biology, making it easier for businesses and research institutes to implement and optimize cell-free protein expression technologies.
In the competitive landscape of the Cell-free Protein Expression Market, numerous key companies are influencing industry dynamics and driving innovation. Leading companies in the cell-free protein expression industry include Thermo Fisher Scientific, Inc., Takara Bio Company, Merck KGaA, New England Biolabs, and Promega Corporation. They provide a diverse range of services. These firms are well-known for their competence in developing cutting-edge technology, tailored solutions, and high-quality reagents for efficient protein expression without the need for living cells. The competitive environment is defined by ongoing R&D efforts to improve protein expression yields, scalability, and protein production techniques.
In September 2023, VantAI, a major essential firm that specializes in drug discovery using artificial intelligence, announced the formation of its latest "Scientific Advisory Board" (SAB). The Scientific Advisory Board members are experts in whole-proteome structural interactomics, generative AI for small molecule drug creation, and protein design.
GLOBAL CELL-FREE PROTEIN EXPRESSION MARKET KEY PLAYERS- DETAILED COMPETITIVE INSIGHTS
Thermo Fisher Scientific, Inc.
Takara Bio Company
Merck KGaA
New England Biolabs
Promega Corporation
Jena Bioscience GmbH
GeneCopoeia, Inc.
Biotechrabbit GmbH
Cube Biotech GmbH
CellFree Sciences Co., Ltd.
Others