Protein Expression Market Size, Share, Growth Analysis, By Product and Service, By System Type, By Application, By End User, By Region

Description

Global Protein Expression Market size was valued at USD 2.90 billion in 2022 and is poised to grow from USD 3.29 billion in 2023 to USD 8.92 billion by 2031, growing at a CAGR of 13.3% in the forecast period (2024-2031).

The protein expression market is experiencing rapid growth due to the increasing demand for recombinant proteins in therapeutic applications, fueled by advancements in biotechnology. The rise of personalized medicine has further accelerated the need for customized protein-based therapies. Ongoing research and development in protein engineering and the artificial production of recombinant proteins are driving market progress. Additionally, technological innovations in protein expression are opening new opportunities to improve patient care through personalized treatments. Strategic collaborations between market players and academic institutions are fostering the development of cutting-edge technologies, including baculovirus and transient expression systems, boosting market expansion.

Top-down and bottom-up approaches were used to estimate and validate the size of the Global Protein Expression market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Global Protein Expression Market Segmental Analysis

Global Protein Expression Market is segmented on the product & service, system type, application, end user, and region. By product and service, the market is segmented into Reagents, Expression Vectors, Competent Cells, Instruments, and Services. By system type, the market is segmented into Mammalian Cell Expression Systems, Prokaryotic Expression Systems, Insect Cell Expression Systems, Yeast Expression Systems, Cell-Free Expression Systems, and Algal-Based Expression Systems. By application, the market is segmented into Therapeutic Applications, Research Applications, and Industrial Applications. By end user, the market is segmented into Pharmaceutical & Biotechnology Companies, Academic Research Institutes, Contract Research Organizations & Contract Development and Manufacturing Organizations (CROs & CDMOs), and Other End Users. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Drivers of the Global Protein Expression Market

The protein expression market is experiencing significant growth, driven by the widespread use of E. coli bacteria for large-scale protein manufacturing. E. coli is the most commonly used expression host due to its well-established genomic and sequencing systems, which streamline cloning processes. This makes E. coli the preferred choice in the pharmaceutical sector for protein expression. Additionally, this method enhances the strength of binding in the promoter region, optimizing transcription and further boosting its adoption. These factors collectively contribute to the rapid expansion of the protein expression market.

Restraints in the Global Protein Expression Market

The Protein Expression market faces significant barriers to entry, particularly for new organizations. High costs associated with protein expression reagents and products are inhibiting market growth, while limited awareness of relevant diseases further discourages investment. This issue is especially prominent in developing countries and for smaller companies with constrained budgets. Additionally, the lack of supportive insurance systems in emerging economies is restricting the adoption of advanced eukaryotic expression system products. These challenges are hindering the market's expansion and preventing many potential players from entering the space.

Market Trends of the Global Protein Expression Market

The Protein Expression market is experiencing significant growth driven by the rising demand for biologics used in treating chronic diseases such as cancer, autoimmune disorders, and other serious conditions. Biologics, which include vaccines, blood components, modified medicinal proteins, antibodies, pegylated proteins, hormones, and enzymes, are essential in protein translation. As these biologic therapies continue to expand in demand, the need for protein expression products and services is growing, further propelling the market's development. This trend highlights the crucial role of protein translation in the creation and delivery of innovative biologic treatments.

Product Code: SQMIG35H2291

Introduction

Objectives of the Study
Definitions
Market Scope

Research Methodology

Information Procurement
Secondary & Primary Data Sources
Market Size Estimation
Market Assumptions & Limitations

Executive Summary

Market Overview Outlook
Supply Demand Trend Analysis
Segmental Opportunity Analysis

Market Dynamics & Outlook

Market Dynamics
- Drivers
- Opportunities
- Restraints
- Challenges
Porters Analysis
- Competitive rivalry
- Threat of Substitute Products
- Bargaining Power of Buyers
- Threat of New Entrants
- Bargaining Power of Suppliers

Key Market Insights

Key Success Factor
Degree of Competition
Top Investment Pockets
Ecosystem of the Market
Pricing Analysis
Technology Analysis
Patent Analysis
Value Chain Analysis
Supply Chain Analysis
Customer & Buying Criteria Analysis
Regulatory Analysis

Protein Expression Market, By Product & Service

Market Overview
Reagents
Expression Vectors
Competent Cells
Instruments
Services

Protein Expression Market, By System Type

Market Overview
Mammalian Cell Expression Systems
- Chinese Hamster Ovary Cell Systems (Cho Cell Systems)
- Human Embryonic Kidney Cell Systems (Hek 293 Cell Systems)
- Other Mammalian Cell Systems
Prokaryotic Expression Systems
- Escherichia Coli Systems
- Other Prokaryotic Expression Systems
Insect Cell Expression Systems
- Baculovirus Systems
- Other Insect Cell Systems
Yeast Expression Systems
- Pichia Systems
- Saccharomyces Systems
- Other Yeast Expression Systems
Cell-Free Expression Systems
Algal-Based Expression Systems

Protein Expression Market, By Application

Market Overview
Therapeutic Applications
Research Applications
Industrial Applications

Protein Expression Market, By End User

Market Overview
Pharmaceutical & Biotechnology Companies
Academic Research Institutes
Contract Research Organizations & Contract Development & Manufacturing Organizations (CROS & CDMOs)
Other End Users

Protein Expression Market Size by Region

Market Overview
North America
- USA
- Canada
Europe
- Germany
- Spain
- France
- UK
- Italy
- Rest of Europe
Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of Asia-Pacific
Latin America
- Brazil
- Rest of Latin America
Middle East & Africa (MEA)
- GCC Countries
- South Africa
- Rest of MEA

Competitive Landscape

Top 5 Player Comparison
Market Positioning of Key Players, 2023
Strategies Adopted by Key Market Players
Recent Activities in the Market
Key Companies Market Share (%), 2023

Key Company Profiles

Thermo Fisher Scientific, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Merck KGaA (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Genscript Biotech Corporation (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Agilent Technologies Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Takara Bio, Inc. (Japan)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Bio-Rad Laboratories, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Qiagen N.V. (Netherlands)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Charles River Laboratories International, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Danaher Corporation (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Sartorius AG (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Corning Incorporated (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Fujifilm Irvine Scientific, Inc. (Acquired by Fujifilm Holdings Corporation) (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Lonza Group AG (Switzerland)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Bioneer Corporation (South Korea)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Promega Corporation (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Oxford Expression Technologies Ltd. (UK)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Proteogenix (France)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Abeomics Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
New England Biolabs, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Promab Biotechnologies (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Sino Biological, Inc. (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Jena Bioscience (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Lifesensors, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Leading Biology, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Peak Proteins (UK)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments

Protein Expression Market Size, Share, Growth Analysis, By Product and Service, By System Type, By Application, By End User, By Region - Industry Forecast 2024-2031