Bone Grafts and Substitutes Market By Type , By Application By End user : Global Opportunity Analysis and Industry Forecast, 2024-2033

Description

The bone grafts and substitutes market was valued at $2.8 billion in 2023, and is projected to reach $4.4 billion by 2033, growing at a CAGR of 4.4% from 2024 to 2033.

Bone grafts and substitutes are devices that are used to replace missing or damaged bone in various medical procedures. They play a crucial role in orthopedics and spinal surgeries. The primary purpose of bone grafts and substitutes is to support the body's natural healing process by providing a scaffold for new bone growth, enhancing the repair and regeneration of bone tissue. Thus, bone grafts and substitutes serve as vital tools in modern medicine, significantly improving patient outcomes in various surgical disciplines.

The growth of the global bone grafts and substitutes market is majorly driven by alarming increase in incidence of orthopedic conditions and rise in cases of fractures and sports injuries. A study published by Wolters Kluwer, a Dutch information services company, stated that approximately two million bone grafting procedures are performed worldwide per year. Among these, 500,000 bone graft are performed annually in the U.S. alone. Moreover, surge in geriatric population significantly contributes toward the market growth. Aged individuals are highly susceptible to bone-related disorders such as osteoporosis and arthritis. This is attributed to the fact that minerals in bones of aged individuals start to leech out, making them brittle, fragile, and easily breakable, thereby necessitating the need for bone harvesters. As per the World Health Organization, the number of people aged 60 years and older was 1 billion in 2019. This number is estimated to increase to 1.4 billion by 2030 and 2.1 billion by 2050. Furthermore, shift in preference toward minimally invasive surgical techniques, which often involve bone grafts and substitutes, is notably contributing to the market growth. In addition, increase in healthcare expenditure, especially in developing regions, is improving the access to advanced orthopedic treatments, including bone grafting procedures, which acts as a significant driving force of the global market. However, high cost associated with bone grafting procedures and risk of immune rejection act as the key deterrent factors of the global market. On the contrary, innovations in graft materials and surgical techniques, such as the development of bioactive and synthetic bone grafts, have expanded the applications and improved the outcomes of bone grafting procedures, which are expected to open new avenues for the growth of the market during the forecast period. For instance, bioactive materials, such as bioactive glass and ceramics, are gaining traction due to their ability to enhance bone regeneration. Moreover, in 2020, the U.S. Food and Drug Administration approved a novel synthetic bone graft substitute designed to enhance bone healing in orthopedic and spinal surgeries, reflecting ongoing advancements and regulatory support in the market.

The global bone grafts and substitutes market analysis is segmented into type, application, end user, and region. On the basis of type, the market is categorized into allografts, bone grafts substitute, and cell-based matrices. Depending on application, it is divided into spinal fusion, trauma, craniomaxillofacial surgery, joint reconstruction, and dental bone grafting. By end user, it is classified into hospitals, specialty clinics, and others. Region wise, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

Key Findings

On the basis of type, the bone grafts substitute segment accounted for the largest share in 2023.

Depending on application, the spinal fusion segment occupied largest bone grafts and substitutes market size in 2023, and is expected to remain dominant by 2033.

By end user, the hospitals segment was the major shareholder in 2023.

Region wise, North America garnered market share in 2023, and is anticipated to continue this trend during the forecast period.

Competition Analysis

Competitive analysis and profiles of the major players in the global bone grafts and substitutes market include Arthrex, Inc, Johnson & Johnson, Medtronic plc, NuVasive, Inc., Stryker Corporation, Zimmer Biomet Holdings, Inc., Baxter International Inc., Xtant Medical Holdings, Inc., Integra LifeSciences, and Orthofix Holdings, Inc. These major players have adopted various key development strategies such as business expansion, new product launches, and partnerships to sustain the intense competition and gain a strong foothold in the global market.

Additional benefits you will get with this purchase are:

Quarterly Update and* (only available with a corporate license, on listed price)
5 additional Company Profile of client Choice pre- or Post-purchase, as a free update.
Free Upcoming Version on the Purchase of Five and Enterprise User License.
16 analyst hours of support* (post-purchase, if you find additional data requirements upon review of the report, you may receive support amounting to 16 analyst hours to solve questions, and post-sale queries)
15% Free Customization* (in case the scope or segment of the report does not match your requirements, 15% is equivalent to 3 working days of free work, applicable once)
Free data Pack on the Five and Enterprise User License. (Excel version of the report)
Free Updated report if the report is 6-12 months old or older.
24-hour priority response*
Free Industry updates and white papers.

Possible Customization with this report (with additional cost and timeline, please talk to the sales executive to know more)

Patient/epidemiology data at country, region, global level
Regulatory Guidelines
Additional company profiles with specific to client's interest
Additional country or region analysis- market size and forecast
Expanded list for Company Profiles
Historic market data
SWOT Analysis

Key Market Segments

By Type

Allografts
- Machined allografts
- Demineralized bone matrix
Bone grafts substitutes
- Bone morphogenic proteins (BMP)
- Synthetic bone grafts
Cell based matrices

By Application

Spinal fusion
Trauma
Joint reconstruction
Dental bone grafting
Craniomaxillofacial

By End User

Hospitals
Specialty clinics
Others

By Region

North America
- U.S.
- Canada
- Mexico
Europe
- France
- Germany
- Italy
- Spain
- UK
- Rest of Europe
Asia-Pacific
- China
- Japan
- India
- South Korea
- Australia
- Rest of Asia-Pacific
LAMEA
- Brazil
- South Africa
- Saudi Arabia
- Rest of LAMEA

Key Market Players:

Arthrex, Inc
Johnson & Johnson
Medtronic plc
NuVasive, Inc.
Stryker Corporation
Zimmer Biomet Holdings, Inc.
Baxter International Inc.
Xtant Medical Holdings, Inc.
Integra LifeSciences
Orthofix Holdings, Inc.

Product Code: A01446

CHAPTER 1: INTRODUCTION

1.1. Report Description
1.2. Key Market Segments
1.3. Key Benefits
1.4. Research Methodology
- 1.4.1. Primary Research
- 1.4.2. Secondary Research
- 1.4.3. Analyst Tools and Models

CHAPTER 2: EXECUTIVE SUMMARY

2.1. CXO Perspective

CHAPTER 3: MARKET LANDSCAPE

3.1. Market Definition and Scope
3.2. Key Findings
- 3.2.1. Top Investment Pockets
- 3.2.2. Top Winning Strategies
3.3. Porter's Five Forces Analysis
- 3.3.1. Bargaining Power of Suppliers
- 3.3.2. Threat of New Entrants
- 3.3.3. Threat of Substitutes
- 3.3.4. Competitive Rivalry
- 3.3.5. Bargaining Power among Buyers
3.4. Market Dynamics
- 3.4.1. Drivers
- 3.4.2. Restraints
- 3.4.3. Opportunities

CHAPTER 4: BONE GRAFTS AND SUBSTITUTES MARKET, BY TYPE

4.1. Market Overview
- 4.1.1 Market Size and Forecast, By Type
4.2. Allografts
- 4.2.1. Key Market Trends, Growth Factors and Opportunities
- 4.2.2. Market Size and Forecast, By Region
- 4.2.3. Market Share Analysis, By Country
- 4.2.5. Machined allografts
  - 4.2.5.1. Market Size and Forecast
- 4.2.6. Demineralized bone matrix
  - 4.2.6.1. Market Size and Forecast
4.3. Bone Grafts Substitutes
- 4.3.1. Key Market Trends, Growth Factors and Opportunities
- 4.3.2. Market Size and Forecast, By Region
- 4.3.3. Market Share Analysis, By Country
- 4.3.5. Bone morphogenic proteins (BMP)
  - 4.3.5.1. Market Size and Forecast
- 4.3.6. Synthetic bone grafts
  - 4.3.6.1. Market Size and Forecast
4.4. Cell Based Matrices
- 4.4.1. Key Market Trends, Growth Factors and Opportunities
- 4.4.2. Market Size and Forecast, By Region
- 4.4.3. Market Share Analysis, By Country

CHAPTER 5: BONE GRAFTS AND SUBSTITUTES MARKET, BY APPLICATION

5.1. Market Overview
- 5.1.1 Market Size and Forecast, By Application
5.2. Spinal Fusion
- 5.2.1. Key Market Trends, Growth Factors and Opportunities
- 5.2.2. Market Size and Forecast, By Region
- 5.2.3. Market Share Analysis, By Country
5.3. Trauma
- 5.3.1. Key Market Trends, Growth Factors and Opportunities
- 5.3.2. Market Size and Forecast, By Region
- 5.3.3. Market Share Analysis, By Country
5.4. Joint Reconstruction
- 5.4.1. Key Market Trends, Growth Factors and Opportunities
- 5.4.2. Market Size and Forecast, By Region
- 5.4.3. Market Share Analysis, By Country
5.5. Dental Bone Grafting
- 5.5.1. Key Market Trends, Growth Factors and Opportunities
- 5.5.2. Market Size and Forecast, By Region
- 5.5.3. Market Share Analysis, By Country
5.6. Craniomaxillofacial
- 5.6.1. Key Market Trends, Growth Factors and Opportunities
- 5.6.2. Market Size and Forecast, By Region
- 5.6.3. Market Share Analysis, By Country

CHAPTER 6: BONE GRAFTS AND SUBSTITUTES MARKET, BY END USER

6.1. Market Overview
- 6.1.1 Market Size and Forecast, By End User
6.2. Hospitals
- 6.2.1. Key Market Trends, Growth Factors and Opportunities
- 6.2.2. Market Size and Forecast, By Region
- 6.2.3. Market Share Analysis, By Country
6.3. Specialty Clinics
- 6.3.1. Key Market Trends, Growth Factors and Opportunities
- 6.3.2. Market Size and Forecast, By Region
- 6.3.3. Market Share Analysis, By Country
6.4. Others
- 6.4.1. Key Market Trends, Growth Factors and Opportunities
- 6.4.2. Market Size and Forecast, By Region
- 6.4.3. Market Share Analysis, By Country

CHAPTER 7: BONE GRAFTS AND SUBSTITUTES MARKET, BY REGION

7.1. Market Overview
- 7.1.1 Market Size and Forecast, By Region
7.2. North America
- 7.2.1. Key Market Trends and Opportunities
- 7.2.2. Market Size and Forecast, By Type
- 7.2.3. Market Size and Forecast, By Application
- 7.2.4. Market Size and Forecast, By End User
- 7.2.5. Market Size and Forecast, By Country
- 7.2.6. U.S. Bone Grafts and Substitutes Market
  - 7.2.6.1. Market Size and Forecast, By Type
  - 7.2.6.2. Market Size and Forecast, By Application
  - 7.2.6.3. Market Size and Forecast, By End User
- 7.2.7. Canada Bone Grafts and Substitutes Market
  - 7.2.7.1. Market Size and Forecast, By Type
  - 7.2.7.2. Market Size and Forecast, By Application
  - 7.2.7.3. Market Size and Forecast, By End User
- 7.2.8. Mexico Bone Grafts and Substitutes Market
  - 7.2.8.1. Market Size and Forecast, By Type
  - 7.2.8.2. Market Size and Forecast, By Application
  - 7.2.8.3. Market Size and Forecast, By End User
7.3. Europe
- 7.3.1. Key Market Trends and Opportunities
- 7.3.2. Market Size and Forecast, By Type
- 7.3.3. Market Size and Forecast, By Application
- 7.3.4. Market Size and Forecast, By End User
- 7.3.5. Market Size and Forecast, By Country
- 7.3.6. France Bone Grafts and Substitutes Market
  - 7.3.6.1. Market Size and Forecast, By Type
  - 7.3.6.2. Market Size and Forecast, By Application
  - 7.3.6.3. Market Size and Forecast, By End User
- 7.3.7. Germany Bone Grafts and Substitutes Market
  - 7.3.7.1. Market Size and Forecast, By Type
  - 7.3.7.2. Market Size and Forecast, By Application
  - 7.3.7.3. Market Size and Forecast, By End User
- 7.3.8. Italy Bone Grafts and Substitutes Market
  - 7.3.8.1. Market Size and Forecast, By Type
  - 7.3.8.2. Market Size and Forecast, By Application
  - 7.3.8.3. Market Size and Forecast, By End User
- 7.3.9. Spain Bone Grafts and Substitutes Market
  - 7.3.9.1. Market Size and Forecast, By Type
  - 7.3.9.2. Market Size and Forecast, By Application
  - 7.3.9.3. Market Size and Forecast, By End User
- 7.3.10. UK Bone Grafts and Substitutes Market
  - 7.3.10.1. Market Size and Forecast, By Type
  - 7.3.10.2. Market Size and Forecast, By Application
  - 7.3.10.3. Market Size and Forecast, By End User
- 7.3.11. Rest of Europe Bone Grafts and Substitutes Market
  - 7.3.11.1. Market Size and Forecast, By Type
  - 7.3.11.2. Market Size and Forecast, By Application
  - 7.3.11.3. Market Size and Forecast, By End User
7.4. Asia-Pacific
- 7.4.1. Key Market Trends and Opportunities
- 7.4.2. Market Size and Forecast, By Type
- 7.4.3. Market Size and Forecast, By Application
- 7.4.4. Market Size and Forecast, By End User
- 7.4.5. Market Size and Forecast, By Country
- 7.4.6. China Bone Grafts and Substitutes Market
  - 7.4.6.1. Market Size and Forecast, By Type
  - 7.4.6.2. Market Size and Forecast, By Application
  - 7.4.6.3. Market Size and Forecast, By End User
- 7.4.7. Japan Bone Grafts and Substitutes Market
  - 7.4.7.1. Market Size and Forecast, By Type
  - 7.4.7.2. Market Size and Forecast, By Application
  - 7.4.7.3. Market Size and Forecast, By End User
- 7.4.8. India Bone Grafts and Substitutes Market
  - 7.4.8.1. Market Size and Forecast, By Type
  - 7.4.8.2. Market Size and Forecast, By Application
  - 7.4.8.3. Market Size and Forecast, By End User
- 7.4.9. South Korea Bone Grafts and Substitutes Market
  - 7.4.9.1. Market Size and Forecast, By Type
  - 7.4.9.2. Market Size and Forecast, By Application
  - 7.4.9.3. Market Size and Forecast, By End User
- 7.4.10. Australia Bone Grafts and Substitutes Market
  - 7.4.10.1. Market Size and Forecast, By Type
  - 7.4.10.2. Market Size and Forecast, By Application
  - 7.4.10.3. Market Size and Forecast, By End User
- 7.4.11. Rest of Asia-Pacific Bone Grafts and Substitutes Market
  - 7.4.11.1. Market Size and Forecast, By Type
  - 7.4.11.2. Market Size and Forecast, By Application
  - 7.4.11.3. Market Size and Forecast, By End User
7.5. LAMEA
- 7.5.1. Key Market Trends and Opportunities
- 7.5.2. Market Size and Forecast, By Type
- 7.5.3. Market Size and Forecast, By Application
- 7.5.4. Market Size and Forecast, By End User
- 7.5.5. Market Size and Forecast, By Country
- 7.5.6. Brazil Bone Grafts and Substitutes Market
  - 7.5.6.1. Market Size and Forecast, By Type
  - 7.5.6.2. Market Size and Forecast, By Application
  - 7.5.6.3. Market Size and Forecast, By End User
- 7.5.7. South Africa Bone Grafts and Substitutes Market
  - 7.5.7.1. Market Size and Forecast, By Type
  - 7.5.7.2. Market Size and Forecast, By Application
  - 7.5.7.3. Market Size and Forecast, By End User
- 7.5.8. Saudi Arabia Bone Grafts and Substitutes Market
  - 7.5.8.1. Market Size and Forecast, By Type
  - 7.5.8.2. Market Size and Forecast, By Application
  - 7.5.8.3. Market Size and Forecast, By End User
- 7.5.9. Rest of LAMEA Bone Grafts and Substitutes Market
  - 7.5.9.1. Market Size and Forecast, By Type
  - 7.5.9.2. Market Size and Forecast, By Application
  - 7.5.9.3. Market Size and Forecast, By End User

CHAPTER 8: COMPETITIVE LANDSCAPE

8.1. Introduction
8.2. Top Winning Strategies
8.3. Product Mapping of Top 10 Player
8.4. Competitive Dashboard
8.5. Competitive Heatmap
8.6. Top Player Positioning, 2023

CHAPTER 9: COMPANY PROFILES

9.1. Arthrex, Inc
- 9.1.1. Company Overview
- 9.1.2. Key Executives
- 9.1.3. Company Snapshot
- 9.1.4. Operating Business Segments
- 9.1.5. Product Portfolio
- 9.1.6. Business Performance
- 9.1.7. Key Strategic Moves and Developments
9.2. Johnson And Johnson
- 9.2.1. Company Overview
- 9.2.2. Key Executives
- 9.2.3. Company Snapshot
- 9.2.4. Operating Business Segments
- 9.2.5. Product Portfolio
- 9.2.6. Business Performance
- 9.2.7. Key Strategic Moves and Developments
9.3. Medtronic Plc
- 9.3.1. Company Overview
- 9.3.2. Key Executives
- 9.3.3. Company Snapshot
- 9.3.4. Operating Business Segments
- 9.3.5. Product Portfolio
- 9.3.6. Business Performance
- 9.3.7. Key Strategic Moves and Developments
9.4. NuVasive, Inc.
- 9.4.1. Company Overview
- 9.4.2. Key Executives
- 9.4.3. Company Snapshot
- 9.4.4. Operating Business Segments
- 9.4.5. Product Portfolio
- 9.4.6. Business Performance
- 9.4.7. Key Strategic Moves and Developments
9.5. Stryker Corporation
- 9.5.1. Company Overview
- 9.5.2. Key Executives
- 9.5.3. Company Snapshot
- 9.5.4. Operating Business Segments
- 9.5.5. Product Portfolio
- 9.5.6. Business Performance
- 9.5.7. Key Strategic Moves and Developments
9.6. Zimmer Biomet Holdings, Inc.
- 9.6.1. Company Overview
- 9.6.2. Key Executives
- 9.6.3. Company Snapshot
- 9.6.4. Operating Business Segments
- 9.6.5. Product Portfolio
- 9.6.6. Business Performance
- 9.6.7. Key Strategic Moves and Developments
9.7. Baxter International Inc.
- 9.7.1. Company Overview
- 9.7.2. Key Executives
- 9.7.3. Company Snapshot
- 9.7.4. Operating Business Segments
- 9.7.5. Product Portfolio
- 9.7.6. Business Performance
- 9.7.7. Key Strategic Moves and Developments
9.8. Xtant Medical Holdings, Inc.
- 9.8.1. Company Overview
- 9.8.2. Key Executives
- 9.8.3. Company Snapshot
- 9.8.4. Operating Business Segments
- 9.8.5. Product Portfolio
- 9.8.6. Business Performance
- 9.8.7. Key Strategic Moves and Developments
9.9. Integra LifeSciences
- 9.9.1. Company Overview
- 9.9.2. Key Executives
- 9.9.3. Company Snapshot
- 9.9.4. Operating Business Segments
- 9.9.5. Product Portfolio
- 9.9.6. Business Performance
- 9.9.7. Key Strategic Moves and Developments
9.10. Orthofix Holdings, Inc.
- 9.10.1. Company Overview
- 9.10.2. Key Executives
- 9.10.3. Company Snapshot
- 9.10.4. Operating Business Segments
- 9.10.5. Product Portfolio
- 9.10.6. Business Performance
- 9.10.7. Key Strategic Moves and Developments