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PUBLISHER: iData Research Inc. | PRODUCT CODE: 1676624
PUBLISHER: iData Research Inc. | PRODUCT CODE: 1676624
Orthopedic Bone Graft Substitute Market Size, Share, and Trends Analysis | Global | 2025-2031 | MedCore | Includes: Allograft Market, Demineralized Bone Matrix Market, and 1 more
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The global bone graft substitute (BGS) market was valued at approximately $2.83 billion in 2024 and is expected to grow at a CAGR of 4.1%, reaching approximately $3.75 billion by 2031. The market includes various types of bone graft substitutes used in orthopedic, trauma, and reconstructive surgeries.
The BGS market is segmented into:
- Allograft BGS
- Demineralized Bone Matrix (DBM) Allograft BGS
- Synthetic BGS
The market is further categorized based on indication type:
- Spine (Cervical, Thoracolumbar)
- Trauma (Non-union, Fresh Fracture)
- Large Joint Reconstruction (Hip, Knee)
- Craniomaxillofacial
- Oncology
- Foot Bone Reconstructions
Market Insights
- Unit Sales & Average Selling Prices
- Market Size & Growth Trends
- Procedure Numbers
- Market Drivers & Limiters
- Market Forecasts Until 2031
- Recent Mergers & Acquisitions
- Competitive Landscape
- Company Profiles & Product Portfolios
Market Trends
- The COVID-19 pandemic caused a decline in BGS sales due to postponed elective surgeries. However, the market recovered strongly by 2022 and resumed steady growth.
- Minimally invasive techniques are driving the adoption of synthetic and DBM-based grafts over traditional bone grafting procedures.
- Rising orthopedic procedures due to an aging population and increasing trauma-related injuries are fueling market growth.
- Technological advancements in bioengineered bone grafts are increasing graft efficiency and patient outcomes.
Market Share Insights
Top Competitors in the Global Bone Graft Substitute Market (2024):
1 Medtronic
* Market leader due to a dominant share in the DBM and synthetic BGS segments.
* Grafton(R) - The first fiber-based DBM allograft BGS and one of the most widely used.
* MASTERGRAFT(R) - Synthetic BGS product line available in granules, moldable putty, flexible strip, and matrix EXT.
2 Stryker
* Second-largest competitor in the market.
* Offers multiple BGS products including Vitoss(TM), ALLOMATRIX(R), FUSIONFLEX(R), and PRO-STIM(R).
3 DePuy Synthes (Johnson & Johnson)
* Third-largest competitor in the BGS market.
* Competes with its DBX(R) DBM product line and chronOS(R) synthetic BGS.
Global Research Scope
- Regions Covered:
* North America: United States, Canada
* Latin America: Brazil, Mexico, Chile, Colombia
* Western Europe: Germany, France, Italy, Spain, United Kingdom
* Central & Eastern Europe: Poland, Russia, Turkey
* Middle East: Saudi Arabia, UAE, Israel
* Asia Pacific: China, Japan, India, South Korea
* Africa: South Africa, Egypt, Nigeria
- Base Year: 2024
- Forecast Period: 2025-2031
- Historical Data: 2021-2023
Quantitative Coverage
- Market Size
- Market Shares
- Market Forecasts
- Market Growth Rates
- Units Sold
- Average Selling Prices
- Procedure Numbers
Qualitative Coverage
- COVID-19 Impact
- Market Growth Trends
- Market Limiters
- Competitive Analysis & SWOT for Top Competitors
- Mergers & Acquisitions
- Company Profiles
- Product Portfolios
- FDA Recalls
- Disruptive Technologies
- Disease Overviews
Data Sources
- Primary Interviews with Industry Leaders
- Government Physician Data
- Regulatory Data
- Hospital Private Data
- Import & Export Data
- iData Research Internal Database
Product Code: iDATA_GLOB25_MC_BGS
TABLE OF CONTENT
- 4.1 Executive Summary
- 4.1.1 Global Orthopedic Bone Graft Substitute Market Overview
- 4.1.2 Competitive Analysis
- 4.1.3 Regions Included
- 4.2 Introduction
- 4.3 Procedure Numbers
- 4.3.1 Total Orthopedic Bone Grafting Procedures
- 4.3.2 Allograft Procedures
- 4.3.3 Demineralized Bone Matrix Procedures
- 4.3.4 Synthetic Procedures
- 4.4 Market Overview
- 4.4.1 By Segment
- 4.4.2 By Region
- 4.5 Market Analysis and Forecast
- 4.5.1 Total Orthopedic Bone Graft Substitute Market
- 4.5.2 Allograft Bone Graft Substitute Market
- 4.5.3 Demineralized Bone Matrix Allograft Bone Graft Substitute Market
- 4.5.4 Synthetic Bone Graft Substitute Market
- 4.5.4.1 Synthetic Bone Graft Substitute Market by Generation Type
- 4.6 Unit Analysis
- 4.6.1 Allograft Bone Graft Substitute Unit Analysis
- 4.6.1.1 Allograft Bone Graft Substitute Units Sold by Indication
- 4.6.1.1.1 Spine Allograft Bone Graft Substitute Units Sold
- 4.6.1.1.2 Trauma Allograft Bone Graft Substitute Units Sold
- 4.6.1.1.3 Large Joint Reconstruction Allograft Bone Graft Substitute Units Sold
- 4.6.2 Demineralized Bone Matrix Allograft Bone Graft Substitute Unit Analysis
- 4.6.2.1 Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold by Indication
- 4.6.2.1.1 Spine Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold
- 4.6.2.1.2 Trauma Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold
- 4.6.2.1.3 Large Joint Reconstruction Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold
- 4.6.3 Synthetic Bone Graft Substitute Unit Analysis
- 4.6.3.1 Synthetic Bone Graft Substitute Units Sold by Indication
- 4.6.3.1.1 Spine Synthetic Bone Graft Substitute Units Sold
- 4.6.3.1.2 Trauma Synthetic Bone Graft Substitute Units Sold
- 4.6.3.1.3 Large Joint Reconstruction Synthetic Bone Graft Substitute Units Sold
- 4.6.1 Allograft Bone Graft Substitute Unit Analysis
- 4.7 Drivers and Limiters
- 4.7.1 Market Drivers
- 4.7.2 Market Limiters
- 4.8 Competitive Market Share Analysis
Product Code: iDATA_GLOB25_MC_BGS
LIST OF CHARTS
- Chart 4-1: Orthopedic Bone Graft Substitute Market, Global, 2024 & 2031
- Chart 4-2: Orthopedic Bone Graft Substitute Procedures, Global, 2024
- Chart 4-3: Orthopedic Bone Grafting Procedures by Segment, Global, 2021- 2031
- Chart 4-4: Orthopedic Bone Graft Substitute Device Market by Segment, Global, 2021 - 2031
- Chart 4-5: Orthopedic Bone Graft Substitute Device Market by Region, Global, 2021 - 2031
- Chart 4-6: Leading Competitors, Orthopedic Bone Graft Substitute Market, Global, 2024
LIST OF FIGURES
- Figure 4-1: Orthopedic Bone Graft Substitute Regions Covered, Global (1 of 2)
- Figure 4-2: Orthopedic Bone Graft Substitute Regions Covered, Global (2 of 2)
- Figure 4-3: Orthopedic Bone Grafting Procedures by Segment, Global, 2021 - 2031
- Figure 4-4: Orthopedic Bone Grafting Procedures by Region, Global, 2021 - 2031
- Figure 4-5: Orthopedic Bone Grafting Procedures by Country, North America, 2021 - 2031
- Figure 4-6: Orthopedic Bone Grafting Procedures by Country, Latin America, 2021 - 2031 (1 of 2)
- Figure 4-7: Orthopedic Bone Grafting Procedures by Country, Latin America, 2021 - 2031 (2 of 2)
- Figure 4-8: Orthopedic Bone Grafting Procedures by Country, Western Europe, 2021- 2031
- Figure 4-9: Orthopedic Bone Grafting Procedures by Country, Central & Eastern Europe, 2021 - 2031 (1 of 2)
- Figure 4-10: Orthopedic Bone Grafting Procedures by Country, Central & Eastern Europe, 2021 - 2031 (2 of 2)
- Figure 4-11: Orthopedic Bone Grafting Procedures by Country, Middle East, 2021 - 2031
- Figure 4-12: Orthopedic Bone Grafting Procedures by Country, Asia-Pacific, 2021- 2031 (1 of 3)
- Figure 4-13: Orthopedic Bone Grafting Procedures by Country, Asia-Pacific, 2021 - 2031 (2 of 3)
- Figure 4-14: Orthopedic Bone Grafting Procedures by Country, Asia-Pacific, 2021 - 2031 (3 of 3)
- Figure 4-15: Orthopedic Bone Grafting Procedures by Country, Africa, 2021 - 2031
- Figure 4-16: Allograft Procedures by Region, Global, 2021- 2031
- Figure 4-17: Allograft Procedures by Country, North America, 2021- 2031
- Figure 4-18: Allograft Procedures by Country, Latin America, 2021- 2031 (1 of 2)
- Figure 4-19: Allograft Procedures by Country, Latin America, 2021- 2031 (2 of 2)
- Figure 4-20: Allograft Procedures by Country, Western Europe, 2021 - 2031
- Figure 4-21: Allograft Procedures by Country, Central & Eastern Europe, 2021 - 2031 (1 of 2)
- Figure 4-22: Allograft Procedures by Country, Central & Eastern Europe, 2021 - 2031 (2 of 2)
- Figure 4-23: Allograft Procedures by Country, Middle East, 2021- 2031
- Figure 4-24: Allograft Procedures by Country, Asia-Pacific, 2021 - 2031 (1 of 3)
- Figure 4-25: Allograft Procedures by Country, Asia-Pacific, 2021 - 2031 (2 of 3)
- Figure 4-26: Allograft Procedures by Country, Asia-Pacific, 2021 - 2031 (3 of 3)
- Figure 4-27: Allograft Procedures by Country, Africa, 2021- 2031
- Figure 4-28: Demineralized Bone Matrix Procedures by Region, Global, 2021- 2031
- Figure 4-29: Demineralized Bone Matrix Procedures by Country, North America, 2021- 2031
- Figure 4-30: Demineralized Bone Matrix Procedures by Country, Latin America, 2021- 2031 (1 of 2)
- Figure 4-31: Demineralized Bone Matrix Procedures by Country, Latin America, 2021- 2031 (2 of 2)
- Figure 4-32: Demineralized Bone Matrix Procedures by Country, Western Europe, 2021 - 2031
- Figure 4-33: Demineralized Bone Matrix Procedures by Country, Central & Eastern Europe, 2021 - 2031 (1 of 2)
- Figure 4-34: Demineralized Bone Matrix Procedures by Country, Central & Eastern Europe, 2021 - 2031 (2 of 2)
- Figure 4-35: Demineralized Bone Matrix Procedures by Country, Middle East, 2021 - 2031
- Figure 4-36: Demineralized Bone Matrix Procedures by Country, Asia-Pacific, 2021- 2031 (1 of 3)
- Figure 4-37: Demineralized Bone Matrix Procedures by Country, Asia-Pacific, 2021- 2031 (2 of 3)
- Figure 4-38: Demineralized Bone Matrix Procedures by Country, Asia-Pacific, 2021 - 2031 (3 of 3)
- Figure 4-39: Demineralized Bone Matrix Procedures by Country, Africa, 2021 - 2031
- Figure 4-40: Synthetic Procedures by Region, Global, 2021 - 2031
- Figure 4-41: Synthetic Procedures by Country, North America, 2021 - 2031
- Figure 4-42: Synthetic Procedures by Country, Latin America, 2021 - 2031 (1 of 2)
- Figure 4-43: Synthetic Procedures by Country, Latin America, 2021 - 2031 (2 of 2)
- Figure 4-44: Synthetic Procedures by Country, Western Europe, 2021- 2031
- Figure 4-45: Synthetic Procedures by Country, Central & Eastern Europe, 2021 - 2031 (1 of 2)
- Figure 4-46: Synthetic Procedures by Country, Central & Eastern Europe, 2021 - 2031 (2 of 2)
- Figure 4-47: Synthetic Procedures by Country, Middle East, 2021 - 2031
- Figure 4-48: Synthetic Procedures by Country, Asia-Pacific, 2021 - 2031 (1 of 3)
- Figure 4-49: Synthetic Procedures by Country, Asia-Pacific, 2021 - 2031 (2 of 3)
- Figure 4-50: Synthetic Procedures by Country, Asia-Pacific, 2021 - 2031 (3 of 3)
- Figure 4-51: Synthetic Procedures by Country, Africa, 2021 - 2031
- Figure 4-52: Orthopedic Bone Graft Substitute Device Market by Segment, Global, 2021 - 2031 (US$M)
- Figure 4-53: Orthopedic Bone Graft Substitute Device Market by Region, Global, 2021 - 2031 (US$M)
- Figure 4-54: Orthopedic Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-55: Units Sold by Region, Orthopedic Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-56: Average Selling Price by Region, Orthopedic Bone Graft Substitute Market, Global, 2021- 2031 (US$)
- Figure 4-57: Market Value by Region, Orthopedic Bone Graft Substitute Market, Global, 2021 - 2031 (US$M)
- Figure 4-58: Allograft Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-59: Units Sold by Region, Allograft Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-60: Average Selling Price by Region, Allograft Bone Graft Substitute Market, Global, 2021 - 2031 (US$)
- Figure 4-61: Market Value by Region, Allograft Bone Graft Substitute Market, Global, 2021 - 2031 (US$M)
- Figure 4-62: Demineralized Bone Matrix Allograft Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-63: Units Sold by Region, Demineralized Bone Matrix Allograft Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-64: Average Selling Price by Region, Demineralized Bone Matrix Allograft Bone Graft Substitute Market, Global, 2021 - 2031 (US$)
- Figure 4-65: Market Value by Region, Demineralized Bone Matrix Allograft Bone Graft Substitute Market, Global, 2021 - 2031 (US$M)
- Figure 4-66: Synthetic Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-67: Units Sold by Region, Synthetic Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-68: Average Selling Price by Region, Synthetic Bone Graft Substitute Market, Global, 2021 - 2031 (US$)
- Figure 4-69: Market Value by Region, Synthetic Bone Graft Substitute Market, Global, 2021 - 2031 (US$M)
- Figure 4-70: Generation 1 Synthetic Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-71: Units Sold by Region, Generation 1 Synthetic Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-72: Average Selling Price by Region, Generation 1 Synthetic Bone Graft Substitute Market, Global, 2021 - 2031 (US$)
- Figure 4-73: Market Value by Region, Generation 1 Synthetic Bone Graft Substitute Market, Global, 2021 - 2031 (US$M)
- Figure 4-74: Generation 2 Synthetic Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-75: Units Sold by Region, Generation 2 Synthetic Bone Graft Substitute Market, Global, 2021 - 2031
- Figure 4-76: Average Selling Price by Region, Generation 2 Synthetic Bone Graft Substitute Market, Global, 2021 - 2031 (US$)
- Figure 4-77: Market Value by Region, Generation 2 Synthetic Bone Graft Substitute Market, Global, 2021 - 2031 (US$M)
- Figure 4-78: Allograft Bone Graft Substitute Units Sold by Indication, Global, 2021 - 2031
- Figure 4-79: Spine Allograft Bone Graft Substitute Units Sold, Global, 2021 - 2031
- Figure 4-80: Trauma Allograft Bone Graft Substitute Units Sold, Global, 2021 - 2031
- Figure 4-81: Large Joint Reconstruction Allograft Bone Graft Substitute Units Sold, Global, 2021- 2031
- Figure 4-82: Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold by Indication, Global, 2021 - 2031
- Figure 4-83: Spine Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold, Global, 2021 - 2031
- Figure 4-84: Trauma Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold, Global, 2021 - 2031
- Figure 4-85: Large Joint Reconstruction Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold, Global, 2021 - 2031
- Figure 4-86: Synthetic Bone Graft Substitute Units Sold by Indication, Global, 2021 - 2031
- Figure 4-87: Spine Synthetic Bone Graft Substitute Units Sold, Global, 2021 - 2031
- Figure 4-88: Trauma Synthetic Bone Graft Substitute Units Sold, Global, 2021 - 2031
- Figure 4-89: Large Joint Reconstruction Synthetic Bone Graft Substitute Units Sold, Global, 2021 - 2031
- Figure 4-90: Leading Competitors, Orthopedic Bone Graft Substitute Market, Global, 2024
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