Cell Expansion Market By Cell Type (Human Cells, Animal Cells), Application (Regenerative Medicine and Stem Cell Research, Cancer & Cell-Based Research), & End-User (Biopharmaceutical & Biotechnology Companies, Research Institutes), Region for 2024-2031

Cell Expansion Market Valuation - 2024-2031

The increasing need for regenerative medicine and innovative therapeutics is driving the growth of the cell expansion market. Regenerative medicine which encompasses stem cell therapy and tissue engineering is significantly dependent on the ability to multiply cells to generate enough material for treatments. As medical technology progresses, there is a greater emphasis on creating therapies that may regenerate damaged tissues and organs providing hope for illnesses with few therapeutic alternatives. Cell expansion enables the large-scale synthesis of cells necessary for these therapies by enabling the market to surpass a revenue of USD 22.67 Billion valued in 2024 and reach a valuation of around USD 93.29 Billion by 2031.

Another important factor driving the cell expansion market is the growing prevalence of chronic diseases and the demand for personalized therapy. Chronic disorders such as cancer, diabetes, and cardiovascular disease necessitate improved treatment strategies that can be personalized to each patient. Cell-based therapies provide tailored treatment choices and the ability to multiply cells is crucial for developing these medicines by enabling the market to grow at a CAGR of 19.34% from 2024 to 2031.

Cell Expansion Market: Definition/ Overview

Cell expansion is a technique used in biotechnology and medical research to generate a high number of cells from a small starting sample. This technology is critical for creating enough cells for a variety of uses including treatments, drug testing, and scientific research. The procedure starts by isolating a certain type of cell such as stem cells or immune cells from a patient or donor. These cells are then placed in a controlled environment with the essential nutrition, growth agents, and conditions to promote proliferation.

Cell expansion is the process of expanding cells in culture to increase their quantity while preserving their properties and functionality. This approach is important in many domains including biomedical research and therapeutic applications. Cell expansion has a substantial significance in regenerative medicine and cell therapy. Stem cells, for example, are cultured to produce adequate amounts for therapeutic use in treating a variety of diseases and injuries.

Cell expansion is the process of replicating cells outside of their normal environment under controlled conditions. This approach has great promise for a variety of industries including biotechnology and medicine. One important prospective application of cell growth is in regenerative medicine. Researchers are looking into techniques to grow stem cells derived from different sources such as bone marrow or adipose tissue, to heal damaged tissues and organs.

Will the Rising Incidence of Chronic Diseases Drive the Cell Expansion Market?

The increasing prevalence of chronic diseases is undoubtedly a big driver of the cell expansion market. Chronic diseases such as cancer, diabetes, and cardiovascular ailments have been continuously expanding over the world creating a growing demand for enhanced therapeutic options. According to the World Health Organization (WHO), chronic diseases account for 71% of all deaths worldwide with cardiovascular disease, cancer, respiratory disease, and diabetes being the primary causes. According to the Centers for Disease Control and Prevention (CDC), six out of every ten persons in the United States have a chronic disease with four out of ten having two or more. This high prevalence highlights the critical need for novel treatments many of which are based on cell expansion technology.

Cell growth is critical in the development of cell-based therapeutics and regenerative medicine, both of which provide promising treatment options for chronic disorders. For example, the National Cancer Institute claims that CAR T-cell therapy which includes growing and altering a patient's T cells has been extremely effective in treating specific types of blood malignancies. Furthermore, the National Institutes of Health (NIH) says that stem cell research which mainly relies on cell growth techniques has the potential to transform the treatment of a variety of chronic illnesses, including heart disease, Alzheimer's, and diabetes. The NIH has raised funding for stem cell research giving more than $2 billion in 2020 alone.

Will Ethical Concerns Regarding Research in Cell Biology Hamper the Cell Expansion Market?

Ethical problems around cell biology research, particularly stem cell research have the potential to influence the cell expansion market. However, the overall impact is likely to be limited due to a variety of circumstances. The scientific community and regulatory organizations have made tremendous strides in addressing ethical concerns through guidelines and oversight procedures. The International Society for Stem Cell Research (ISSCR) changes its rules regularly; the most recent version was released in 2021, and it provides a framework for responsible research. Furthermore, many countries have formed national committees to monitor and regulate stem cell research. For example, the UK's Human Fertilisation and Embryology Authority (HFEA) reported authorizing 26 research projects using human embryos in 2020-2021 demonstrating that research is continuing despite ethical concerns.

Furthermore, the public's image of stem cell research has gradually improved. According to a 2020 Pew Research Center survey, 65% of respondents in the United States support embryonic stem cell research up from 51% in 2002. This shift in public sentiment combined with the potential medical benefits of cell-based therapies is expected to fuel further investment and study in the sector. This rise indicates that while ethical considerations may influence research procedures, they are unlikely to have a large impact on the total cell expansion business. Furthermore, the growing emphasis on alternate cell sources such as induced pluripotent stem cells (iPSCs) and adult stem cells helps to alleviate some of the ethical issues raised about embryonic stem cells.

Category-Wise Acumens

Will Rising Demand for Cell-Based Therapies and Regenerative Medicine Influence the Cell Type Segment?

Human cells are now the prominent sector in the cell expansion market owing to the growing area of regenerative medicine and the increasing need for cell-based therapies. Human cells particularly stem cells produced from bone marrow, adipose tissue, and umbilical cord blood are critical for creating therapies that repair or replace damaged tissues and organs. The capacity to expand these cells in vitro enables researchers and doctors to generate large amounts for therapeutic applications such as treating cardiovascular ailments, neurological problems, and autoimmune conditions. The promise of personalized medicine, in which medications are tailored to individual patients based on their genetic composition and specific medical needs drives rising demand for human cell expansion technology.

While human cells dominate due to their medicinal potential, animal cells continue to have a large representation in the cell expansion market owing to their importance in research and biopharmaceutical applications. Animal cells, especially mammalian cells such as CHO (Chinese hamster ovary) cells are critical in the development of vaccines, biologics, and other pharmaceuticals. CHO cells, for example, are commonly employed to produce therapeutic proteins and monoclonal antibodies for cancer, autoimmune illnesses, and infectious diseases. Their strong track record in bioprocessing combined with advances in genetic engineering and cell line research has strengthened their position in biopharmaceutical manufacturing.

Will the Transformative Potential of Cell-Based Therapies in Healthcare Drive Growth in the Application Segment?

Regenerative medicine and stem cell research have emerged as the most popular application areas owing to the revolutionary potential of cell-based therapeutics in healthcare. Stem cells with their unique ability to develop into multiple specialized cell types show promise for rebuilding damaged tissues and organs. This application covers a wide range of therapeutic areas such as cardiovascular diseases, neurological disorders, orthopedic injuries, and autoimmune ailments. Researchers and physicians are increasingly looking into stem cell therapies to discover novel treatments that meet unmet medical needs and perhaps heal previously untreatable illnesses.

Regenerative medicine and stem cell research dominate the cell expansion market due to their wide range of therapeutic applications and potential to transform healthcare; however, other applications such as vaccine production, drug discovery, and gene therapy also contribute to market growth. Vaccine manufacture relies on cell multiplication to culture cells that can efficiently produce viral antigens or other vaccine components. Expanded cells aid in drug development by allowing for high-throughput screening procedures which speed up the identification of new drug candidates.

Country/Region-wise Acumens

Will the Rise in Funding Initiatives by Government Agencies Drive the Growth in the North American Region?

The United States dominates the North American cell expansion industry owing to its strong research infrastructure, significant government support, and high adoption of modern biotechnologies. The presence of large pharmaceutical and biotechnology corporations as well as premier academic and research institutions reinforces the region's dominant position.

The increase in funding initiatives by government organizations is a key driver of growth in the North American cell expansion industry. The National Institutes of Health (NIH), the principal source of biomedical research funding in the United States has steadily expanded its budget allocation for stem cell research.

The impact of government money goes beyond direct research support. It has encouraged relationships between academics and industry resulting in the formation of specialized research institutes and the training of qualified workers. For example, the NIH-funded National Center for Advancing Translational Sciences (NCATS) has helped to bridge the gap between laboratory discoveries and clinical applications in cell therapy. The United States Food and Drug Administration (FDA) has also played an important role by introducing programs such as the Regenerative Medicine Advanced Therapy (RMAT) designation which has sped up the development and review of cell therapies.

Will the Increasing Initiatives by Local Pharmaceutical and Biotechnology Companies Boost the Market in the Asia Pacific Region?

The Asia-Pacific region is expected to see the greatest growth in the cell expansion industry, owing to increased activities by local pharmaceutical and biotechnology businesses. This rapid rise is being driven by government backing, increased funding, and an increasing emphasis on regenerative medicine and cell-based therapies. The expanding endeavors of local pharmaceutical and biotechnology businesses in the Asia Pacific region are fueling the cell expansion industry. This tendency is supported by several important drivers and statistics. To begin, the government is steadily increasing its support for biotechnology and life sciences research. For example, China's 14th Five-Year Plan (2021-2025) promotes the growth of the biotechnology industry as a national strategic priority committing major resources to it.

According to the World Health Organization, noncommunicable illnesses account for 71% of all deaths worldwide with a substantial proportion occurring in Asia Pacific countries. This health burden is spurring more studies into cell-based therapies as possible cures. Furthermore, the region's big and aging population creates a significant business opportunity. The United Nations predicts that by 2050, one in every four individuals in Asia and the Pacific will be over the age of 60 creating an increasing demand for regenerative medicine treatments. Finally, advancements in hospital infrastructure and increased healthcare spending are boosting the use of sophisticated cell therapies.

Competitive Landscape

The cell expansion market is a dynamic and competitive space, characterized by a diverse range of players vying for market share. These players are on the run for solidifying their presence through the adoption of strategic plans such as collaborations, mergers, acquisitions, and political support. The organizations are focusing on innovating their product line to serve the vast population in diverse regions.

Some of the prominent players operating in the cell expansion market include:

Thermo Fisher Scientific, Inc.

Corning Incorporated

Merck KGaA

Miltenyi Biotec

BD (Becton, Dickinson, and Company)

Terumo BCT, Inc.

Sartorius AG

Takara Bio, Inc.

TRINOVA BIOCHEM GmbH

Upcyte Technologies GmbH

Latest Developments

In April 2022, STEMCELL Technologies Canada and Applied Cells Inc. collaborated to develop a new method of cell separation by combining Applied Cells' MARS platform with STEMCELL's EasySep kits making isolating cells from varied samples easier and more automatic.

In May 2023, panCELLa and BioCentriq formed a research partnership to investigate stem cell-derived natural killer cell growth technologies. The partnership intends to examine panCELLa's genetically altered feeder cells for their ability to improve the expansion rate, total yield, and potency of produced NK cells.

Cell Expansion Market, By Category

• Cell Type:
• Human Cells
• Animal Cells
• Application:
• Regenerative Medicine and Stem Cell Research
• Cancer & Cell-Based Research
• Other Applications
• End-User:
• Biopharmaceutical & Biotechnology Companies
• Research Institutes
• Cell Banks
• Others
• Region:
• North America
• Europe
• Asia-Pacific
• South America
• Middle East & Africa