PUBLISHER: The Business Research Company | PRODUCT CODE: 1712749
PUBLISHER: The Business Research Company | PRODUCT CODE: 1712749
Protein inhibitors are compounds that disrupt the cellular process involved in creating new proteins. They specifically target the steps in protein synthesis within cells, operating at the level of the ribosome. This is possible due to the distinct structural differences between prokaryotic and eukaryotic ribosomes.
The primary types of protein inhibitors include protein kinase inhibitors, monoclonal antibodies, and other related compounds. Monoclonal antibodies, created in laboratories, mimic or enhance the immune system's attack on unwanted cells, such as cancer cells, effectively acting as substitute antibodies. These protein inhibitors find application in treating conditions like oncology (cancer) and inflammatory diseases. They are distributed through various channels including hospital pharmacies, independent pharmacies, and online pharmacies to reach patients in need of these treatments.
The protein inhibitors market research report is one of a series of new reports from The Business Research Company that provides protein inhibitors market statistics, including protein inhibitors industry global market size, regional shares, competitors with a protein inhibitors market share, detailed protein inhibitors market segments, market trends and opportunities, and any further data you may need to thrive in the protein inhibitors industry. This protein inhibitors market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The protein inhibitors market size has grown strongly in recent years. It will grow from $80.99 billion in 2024 to $88.74 billion in 2025 at a compound annual growth rate (CAGR) of 9.6%. The growth in the historic period can be attributed to drug discovery, drug development, cancer treatment, regulatory approvals.
The protein inhibitors market size is expected to see strong growth in the next few years. It will grow to $125.26 billion in 2029 at a compound annual growth rate (CAGR) of 9.0%. The growth in the forecast period can be attributed to precision medicine, immunotherapy, drug combinations, aging population. Major trends in the forecast period include data sharing and collaboration, sustainability and ESG, personalized medicine, and adaptive clinical trials.
The rising incidence of chronic diseases is expected to drive the growth of the protein inhibitors market during the forecast period. Conditions such as cancer, cardiovascular diseases, and autoimmune disorders are becoming increasingly common. For example, in June 2024, the National Health Service, a publicly funded healthcare system in England, reported that there were 3,615,330 individuals registered with a general practitioner who had non-diabetic hyperglycemia, or pre-diabetes, in 2023. This represents a significant increase from 3,065,825 in 2022, amounting to an increase of nearly 18%. Consequently, the growing number of individuals suffering from chronic diseases is likely to enhance the demand for protein inhibitors in the market.
The increasing demand for personalized medicine is anticipated to drive the growth of the protein inhibitors market in the future. Personalized medicine customizes medical treatments based on an individual's unique genetic composition, resulting in more effective and precise healthcare interventions. Protein inhibitors play a vital role in personalized medicine by targeting specific proteins to address diseases according to a person's genetic profile. For example, in February 2024, the Personalized Medicine Coalition, a professional membership organization based in the US, reported that the FDA approved 16 new personalized treatments for patients with rare diseases in 2023, a significant rise from six in 2022. Of the 35 new molecular entities (NMEs) approved, about 34% or 12 are classified as personalized medicines by the Personalized Medicine Coalition (PMC). Thus, the growing interest in personalized medicine is fueling the expansion of the protein inhibitors market.
Leading companies in the protein inhibitor market are increasingly focusing their investments on strategic initiatives, including partnerships and collaborations, to develop new drugs that align with market demand. These strategic alliances enable companies to broaden their product portfolios and expand their geographical reach. For example, in July 2024, Genentech Inc., a US-based biotechnology firm, entered into a collaboration with Relay Therapeutics to develop protein inhibitors, particularly the SHP2 inhibitor RLY-1971 (also known as migoprotafib or GDC-1971). This partnership started with an initial investment of $75 million in 2021, accompanied by an additional $45 million in milestone payments, bringing the total investment to over $120 million before its conclusion. The collaboration aimed to investigate the therapeutic potential of RLY-1971 in conjunction with Genentech's KRAS G12C inhibitor, GDC-6036, for treating advanced solid tumors, including colorectal cancer.
Key players in the protein inhibitors market are prioritizing the development of tyrosine kinase 2 (TYK2) inhibitors, positioning themselves competitively. TYK2 inhibitors, instrumental in treating specific autoimmune conditions by blocking the TYK2 enzyme involved in immune system responses, are a significant focus. For instance, Bristol-Myers Squibb Company gained FDA approval in September 2022 for Sotyktu (deucravacitinib), an oral medication specifically for adults with moderate-to-severe plaque psoriasis eligible for systemic therapy or phototherapy. Sotyktu stands as the first oral treatment with selective inhibition of TYK2 through allosteric mechanisms, marking a significant advancement in this segment of the market.
In June 2022, Pfizer Inc., a US-based pharmaceutical and biotechnology company, acquired ReViral for $525 million. The acquisition strengthens Pfizer's commitment to creating both medications and vaccines to help fight the respiratory syncytial virus while also expanding its anti-infective portfolio (RSV). ReViral is a UK-based clinical-stage biopharmaceutical company pioneering in the discovery and development of innovative antiviral drugs for disorders brought on by the respiratory syncytial virus.
Major companies operating in the protein inhibitors market include Bayer AG, AstraZeneca plc, F. Hoffmann-La Roche Ltd., Teva Pharmaceutical Industries Ltd., Apotex Inc., Novartis International AG, GlaxoSmithKline plc, Pfizer Inc., Boehringer Ingelheim International GmbH, Abbott Laboratories, Amgen Inc., Baxter International Inc., Merck & Co. Inc., Interprotein Corporation, AbbVie Inc., Bristol Myers Squibb Company, Galapagos NV, Priovant Therapeutics Inc., Tempus Labs Inc., ReCode Therapeutics Inc., Satellite Bio Inc., Ambagon Therapeutics Inc., Biogen Inc., Eli Lilly and Company, Gilead Sciences Inc., Johnson & Johnson, Regeneron Pharmaceuticals Inc., Sanofi S.A., Takeda Pharmaceutical Company Limited, Vertex Pharmaceuticals Inc., Lonza Group AG, Catalent Inc., Thermo Fisher Scientific Inc., Charles River Laboratories International Inc., WuXi AppTec Co. Ltd.
North America was the largest region in the protein inhibitors market in 2024. The regions covered in the protein inhibitors market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
The countries covered in the protein inhibitors market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Italy, Spain, Canada
The protein inhibitors market consists of sales of erythromycin, tetracycline, chloramphenicol, and aminoglycosides. Values in this market are factory gate values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Protein Inhibitors Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on protein inhibitors market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for protein inhibitors ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The protein inhibitors market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.