PUBLISHER: The Business Research Company | PRODUCT CODE: 1668530
PUBLISHER: The Business Research Company | PRODUCT CODE: 1668530
Proteinase K, a serine protease derived from the mold Tritirachium album, serves as a valuable enzyme for the deactivation of protein contaminants in sample preparations. Widely utilized in DNA extraction processes, this enzyme comes in two primary forms lyophilized powder and liquid.
The lyophilized powder form is obtained through a dehydration process involving freezing and vacuum removal of water. Proteinase K finds applications across various therapeutic areas such as infectious diseases, diabetes, oncology, cardiology, nephrology, autoimmune diseases, and neurology. Its uses extend to isolation and purification of genomic DNA and RNA, in situ hybridization, mitochondria isolation, and enzyme removal.Target customers for Proteinase K include contract research organizations, academic institutes, biotechnology companies, and diagnostics laboratories. Its role in facilitating the efficient processing of samples makes it a key component in research and diagnostic workflows within the specified industries and applications.
The proteinase k market research report is one of a series of new reports from The Business Research Company that provides proteinase k market statistics, including proteinase k industry global market size, regional shares, competitors with a proteinase k market share, detailed proteinase k market segments, market trends and opportunities, and any further data you may need to thrive in the proteinase k industry. This proteinase k market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The proteinase K market size has grown strongly in recent years. It will grow from$4.89 billion in 2024 to $5.36 billion in 2025 at a compound annual growth rate (CAGR) of 9.7%. The growth in the historic period can be attributed to expanding biotechnology and life sciences research, diagnostic testing advancements, pharmaceutical development needs, bioprocessing and protein purification, quality control in food and beverages
The proteinase K market size is expected to see rapid growth in the next few years. It will grow to $8.19 billion in 2029 at a compound annual growth rate (CAGR) of 11.2%. The growth in the forecast period can be attributed to continued growth in molecular diagnostics, advancements in precision medicine, biopharmaceutical manufacturing expansion, research in proteomics and genomics, and increased application in forensic sciences. Major trends in the forecast period include pharmaceutical industry growth, technological advancements, market competition and pricing, sustainable and animal-free variants, and global pandemic impact.
The anticipated growth of the proteinase K market is expected to be driven by the increasing prevalence of chronic diseases. Chronic diseases, lasting more than a year and requiring continuous medical treatment, are a significant target for proteinase K usage. The enzyme plays a crucial role in both preventative and therapeutic applications, facilitating the extraction and isolation of DNA and RNA from viruses associated with various chronic diseases. For instance, data from the National Library of Medicine in January 2023 projected a rise in the number of individuals aged 50 and older with at least one chronic condition in the US, reaching 142.66 million by 2050. This underscores the growing significance of proteinase K in addressing the needs of a population grappling with chronic diseases.
The rising incidence of infectious diseases, particularly tuberculosis, is projected to drive growth in the proteinase K market in the future. Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis, which primarily affects the lungs but can also impact other areas of the body. Proteinase K is used in TB research for the extraction and isolation of DNA and RNA from the Mycobacterium tuberculosis bacterium. For example, in February 2024, the UK government department GOV.UK reported a 10.7% increase in tuberculosis cases in England in 2023, rising from 4,380 in 2022 to 4,850. Thus, the growing incidence of infectious diseases like tuberculosis is expected to boost the proteinase K market.
The proteinase K market is witnessing a notable trend towards product innovation, with major companies actively launching novel products to strengthen their positions. One such example is Biocatalysts Ltd., a UK-based biotechnology company, which introduced Proteocut K. This high-quality and cost-effective alternative to liquid proteinase K is a subtilisin-type serine protease with broad substrate specificity, suitable for a variety of life science applications. Its efficient hydrolysis of various proteins is attributed to its broad pH profile (6.0 - 10.0) and temperature range (40 -70°C). This innovative offering enhances the choices available in the proteinase K market, providing users with a versatile enzyme solution.
Companies are focused on continuous product development to stay competitive. ArcticZymes Technologies ASA, a Norway-based biotechnology company, exemplifies this by upscaling production and launching a glycerol-free version of ArcticZymes Proteinase. Known for its high activity and stability, this enzyme is valuable in molecular biology protocols, diagnostics, and bioprocessing. The glycerol-free variant offers enhanced stability at -20°C for up to one year, making it suitable for lyophilization and automated processes.
In January 2023, Lighthouse Pharma, a US-based biopharmaceutical company, acquired the small molecule proteinase inhibitor portfolio from Quince Therapeutics Inc. This acquisition positions Lighthouse Pharma to advance the development of gingipain inhibitors for dementia and other disorders, offering innovative treatment options. Quince Therapeutics Inc., a US-based biotechnology company specializing in proteinase inhibitors, contributes valuable assets to Lighthouse Pharma's research and development efforts.
Major companies operating in the proteinase K market include Merck KGaA, QIAGEN NV, Thermo Fisher Scientific Inc., F Hoffmann-La Roche Ltd., Worthington Biochemical Corporation, Sigma-Aldrich Co. LLC, Behemoth Inteligencia para os Negocios LTDA, Codexis Inc., Beijing SBS Genetech Co. Ltd, Hoffmann-La Roche Ltd, Amicogen Inc, Amano Enzyme Inc., Sisco Research Laboratories Pvt. Ltd., Promega Corporation, Bioline Diagnostics LLP, Biocompare, BioVision Inc., Creative Enzymes, G-Biosciences, Advanced Enzymes Technologies, Cell Signaling Technology Inc., Dyadic International, Amresco LLC, Abcam plc, Bio Basic Inc., BioChain Institute Inc., BioLegend Inc., Bio-Rad Laboratories Inc., Enzo Life Sciences Inc., GenScript Biotech Corporation
North America was the largest region in the global proteinase k market in 2024. Asia-Pacific is expected to be the fastest-growing region in the global proteinase k market during the forecast period. The regions covered in the proteinase k market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
The countries covered in the proteinase k market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain
The proteinase K market consists of sales of acid proteinase, neutral proteinase, and alkaline proteinase. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Proteinase K Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on proteinase k market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for proteinase k ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The proteinase k market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.