PUBLISHER: The Business Research Company | PRODUCT CODE: 1667758
PUBLISHER: The Business Research Company | PRODUCT CODE: 1667758
Gene synthesis involves the chemical synthesis of a DNA (deoxyribonucleic acid) strand, building it base by base. This process finds applications in various fields, including the creation of recombinant DNA molecules, protein engineering, gene therapy, and synthetic biology.
The primary methods for gene synthesis include solid-phase synthesis, chip-based synthesis, and PCR-based enzyme synthesis. Solid-phase synthesis is a chemical compound synthesis method where the reactant molecule is attached to an insoluble material, and reagents are introduced in the solution phase. This encompasses diverse gene synthesis services such as antibody DNA synthesis, viral DNA synthesis, and others. These services find applications in gene and cell therapy development, vaccine development, disease diagnosis, among others. Gene synthesis is utilized by different end-users, including biotechnology and pharmaceutical companies, academic and government research institutes, as well as contract research organizations.
The gene synthesis market research report is one of a series of new reports from The Business Research Company that provides gene synthesis market statistics, including the gene synthesis industry's global market size, regional shares, competitors with a gene synthesis market share, detailed gene synthesis market segments, market trends and opportunities, and any further data you may need to thrive in the gene synthesis industry. This gene synthesis market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The gene synthesis market size has grown rapidly in recent years. It will grow from$3.32 billion in 2024 to $3.98 billion in 2025 at a compound annual growth rate (CAGR) of 19.7%. The growth in the historic period can be attributed to advancements in genetic research, a rise in personalized medicine, an increased focus on biotechnology, growth in the biopharmaceutical sector, and technological platforms for synthesis
The gene synthesis market size is expected to see exponential growth in the next few years. It will grow to $8.67 billion in 2029 at a compound annual growth rate (CAGR) of 21.5%. The growth in the forecast period can be attributed to the rapid growth of synthetic biology, the emergence of CRISPR technology, increasing demand for custom genes, advances in gene editing and therapy, and expanding applications in agriculture. Major trends in the forecast period include increasing accessibility through cost reduction, customized gene libraries for functional genomics, automation, and high-throughput synthesis, collaborations in biotechnology and pharmaceutical sectors, and focus on ethical and regulatory considerations.
The rising prevalence of chronic infectious diseases is anticipated to drive the growth of the gene synthesis market in the future. Chronic infectious diseases are illnesses caused by pathogens that can persist in the body for extended periods, often lasting for years or even a lifetime. Gene synthesis plays a vital role in combating infectious diseases by facilitating the development of new vaccines, diagnostics, and therapeutics tailored to specific pathogens. This method offers a faster, more effective, and targeted approach compared to traditional methods, which can help manage outbreaks of infectious diseases. For instance, in November 2023, the World Health Organization, a specialized health agency based in Switzerland, reported that in 2022, approximately 10.6 million people worldwide were diagnosed with tuberculosis (TB), including 5.8 million men, 3.5 million women, and 1.3 million children. Thus, the increase in chronic infectious diseases is driving the growth of the gene synthesis market.
The growing demand for biofuels is projected to drive the expansion of the gene synthesis market in the future. Biofuels are renewable energy sources obtained from organic materials, such as plants or animal waste, serving as alternatives to conventional fossil fuels. Gene synthesis is utilized in biofuel production to engineer microorganisms with improved metabolic pathways, enabling more efficient conversion of organic materials into biofuels. For example, in May 2022, the International Energy Agency, a France-based intergovernmental organization, reported a 9% growth in biofuel demand in 2022, followed by an additional 12% increase in 2023, reflecting a consistent upward trend in consumption. Therefore, the rising demand for biofuels is a key factor driving the gene synthesis market.
Leading companies in the gene synthesis market are concentrating on delivering advanced platforms, such as silicon-based DNA synthesis technologies, to address the demand for faster delivery and enhance their competitive position. A silicon-based DNA synthesis platform employs silicon wafers to enable the miniaturization of the chemical reactions required for DNA creation during the gene synthesis process. For example, in November 2023, Twist Bioscience Corporation, a biotechnology firm based in the US, introduced Twist Express Genes, a rapid gene synthesis service with a turnaround time of five to seven business days. This service utilizes a silicon-based DNA synthesis platform to meet customer expectations for quicker delivery. The Express Genes service is designed for researchers in both industry and academia who purchase DNA from suppliers and independently synthesize genes, offering a comprehensive solution for their gene production needs. Additionally, GenScript ensures plasmid yield and 100% sequence accuracy, upholding high standards of quality and reliability in its products.
Major players in the gene synthesis market are channeling their efforts into offering innovative services that leverage advanced platforms, such as silicon-based DNA synthesis platforms. These platforms aim to address the growing demand for expedited delivery, providing a competitive edge. For instance, in November 2023, Twist Bioscience, a US-based biotechnology company, launched Express Genes, a rapid gene synthesis service promising a turnaround time of five to seven business days. Leveraging a silicon-based DNA synthesis platform, this service caters to researchers in both industry and academia who seek faster gene delivery. Express Genes seeks to offer a comprehensive solution for gene production needs, accommodating researchers who purchase DNA from suppliers and those independently synthesizing genes.
In January 2023, Moderna Inc., a biotechnology company based in the United States, acquired OriCiro Genomics for an undisclosed amount. This acquisition is intended to enhance OriCiro Genomics' capabilities in mRNA manufacturing and expedite the development of its therapeutic and vaccine portfolio. OriCiro Genomics is a biotechnology firm located in Japan that specializes in synthetic biology and DNA synthesis technologies.
Major companies operating in the gene synthesis market market include Genscript Biotech Corporation, Brooks Automation Inc., Boster Biological Technology Ltd., Twist Bioscience Corp., ProteoGenix Inc., Biomatik Corporation, ProMab Biotechnologies Inc., Thermo Fisher Scientific Inc., Integrated DNA Technologies Inc., OriGene Technologies Inc., GenScript Corp., Eurofins Scientific SE, Merck KGaA, Codex DNA Inc., Genewiz Inc., Eurofins Genomics LLC, BioCat GmbH, Bioneer Pacific Co. Ltd., Bio Basic Inc., Beijing SBS Genetech Co. Ltd, Creative Biogene Inc, Exonbio LLC., Trenzyme GmbH, AddLife AB, Polygen GmbH, MACROGEN CO. LTD., Synbio Technologies LLC
North America was the largest region in the gene synthesis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the global gene synthesis market report during the forecast period. The regions covered in the gene synthesis market market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
The countries covered in the gene synthesis market market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain
The gene synthesis market includes revenues earned by entities by providing custom gene synthesis services, selling pre-made DNA constructs, genetic engineering, vaccine development, antibody discovery, protein engineering, licensing technology, forming partnerships, and collaborating on research projects. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Gene Synthesis Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on gene synthesis market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for gene synthesis market ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The gene synthesis market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.