PUBLISHER: The Business Research Company | PRODUCT CODE: 1662353
PUBLISHER: The Business Research Company | PRODUCT CODE: 1662353
Structural biology focuses on examining the three-dimensional structures of essential molecules and macromolecules within biological systems, such as sugars, proteins, and nucleic acids. Molecular modeling involves the creation, visualization, and modification of these three-dimensional structures of chemical and biological molecules, along with identifying physicochemical properties that can help interpret the structural activity relationship (SAR) of the biological molecules.
The primary tools employed in structural biology and molecular modeling encompass Software as a Service (SaaS) and standalone modeling software, visualization and analysis tools, databases, and other specialized utilities. SaaS operates through a cloud-based framework, hosted by a provider and accessible to end-users online, while standalone software requires installation and maintenance on the user's computer, necessitating the user's management of the program and hardware, unless covered by provided software maintenance and support. SaaS and standalone modeling tools serve specific functions within predefined parameters. These techniques find extensive application in various domains such as drug development, drug discovery, and other pharmaceutical, biotechnological, academic, and clinical trial endeavors.
The structural biology and molecular modelling techniques market research report is one of a series of new reports from The Business Research Company that provides structural biology and molecular modelling techniques market statistics, including structural biology and molecular modelling techniques industry global market size, regional shares, competitors with a structural biology and molecular modelling techniques market share, detailed structural biology and molecular modelling techniques market segments, structural biology and molecular modeling techniques market trends and opportunities, and any further data you may need to thrive in the structural biology and molecular modelling techniques industry. This structural biology and molecular modelling techniques market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The structural biology and molecular modeling techniques market size has grown rapidly in recent years. It will grow from $8.78 billion in 2024 to $10.35 billion in 2025 at a compound annual growth rate (CAGR) of 17.9%. The growth in the historic period can be attributed to emergence of cryo-electron microscopy, pharmaceutical research and drug discovery, understanding enzyme mechanisms, growth in structural genomics initiatives, validation of drug targets, structural insights into viral proteins, drug resistance studies.
The structural biology and molecular modeling techniques market size is expected to see rapid growth in the next few years. It will grow to $20.36 billion in 2029 at a compound annual growth rate (CAGR) of 18.4%. The growth in the forecast period can be attributed to expansion of fragment-based drug design, advancements in hybrid methods, rapid expansion of structural proteomics, precision medicine applications in oncology, structural biology in neuroscience research, application in RNA biology, advancements in structural bioinformatics. Major trends in the forecast period include integration of artificial intelligence (ai), hybrid methods for structural determination, single-particle analysis in cryo-EM, membrane protein structures, open-source software development, NMR spectroscopy, structural biology in personalized medicine, technological advances in x-ray crystallography.
The rising incidence of chronic diseases is anticipated to drive the growth of the structural biology and molecular modeling techniques market. Chronic diseases are often defined as conditions that persist for three months or longer and can worsen over time. Common chronic diseases include cancer, heart disease, stroke, diabetes, and arthritis. Structural biology is being employed to explore the origins of these illnesses, and structure-guided methodologies have shown contributions to various aspects of early drug discovery, both computationally and empirically. Understanding structure can help reveal the effects of genetic mutations associated with human diseases and the resistance encountered in treatments for cancer and infectious diseases. For example, in June 2024, the Australian Institute of Health and Welfare, a government agency in Australia, reported that the death rate linked to chronic conditions increased from 459 per 100,000 in 2021 to 490 per 100,000 in 2022, indicating a significant rise. Therefore, the growing prevalence of chronic diseases is propelling the growth of the structural biology and molecular modeling techniques market.
The increasing embrace of personalized medicine is expected to accelerate the growth of the structural biology and molecular modeling techniques market in the future. Personalized medicine is a groundbreaking healthcare strategy that customizes medical treatments and interventions to match the unique characteristics of each patient. Structural biology and molecular modeling techniques are vital to personalized medicine as they facilitate the identification and validation of molecular targets, assist in drug discovery and development, elucidate genetic variations, forecast drug-target interactions, optimize drug delivery, and contribute to biomarker discovery. For instance, in 2022, the Personalized Medicine Coalition, a professional membership organization based in the US, reported that the Food and Drug Administration's Center for Drug Evaluation and Research (CDER) approved 37 new molecular entities (NMEs) that year. Among the 35 therapeutic NMEs, around 34%, equivalent to 12 of them, were categorized as personalized medicines by the Personalized Medicine Coalition (PMC). Thus, the rising adoption of personalized medicine is fueling the growth of the structural biology and molecular modeling techniques market.
Technological advancements are a significant trend gaining traction in the structural biology and molecular modeling techniques market. Leading companies in the industry are creating innovative technologies, such as next-generation sequencing-based ctDNA testing, in silico screening of 3-D chemical structures, and advanced software solutions, to maintain their competitive edge. For example, in March 2022, PerkinElmer Inc., a US-based provider of products, solutions, and services for the applied sciences, life sciences, and diagnostics sectors, introduced ChemDraw V21 software. This tool allows for quick native import, animation, and sharing of 3D chemical structures in Microsoft PowerPoint. This crucial enhancement streamlines the process for chemists, enabling them to produce more insightful research reports. With the new ChemDraw V21 software, scientists can effortlessly paste a live 3D representation of their molecule into the Microsoft PowerPoint application, where they can view, rotate, and share the image while fully preserving its atom and bond color highlights.
Major players in the structural biology and molecular modeling techniques market are developing new models, such as AI cloud services, to secure a competitive advantage. AI cloud services encompass the provision of artificial intelligence capabilities and tools through cloud computing platforms, allowing businesses and developers to access, deploy, and scale AI applications without requiring extensive on-premises infrastructure. For instance, in March 2023, Nvidia Corporation, a US-based software company, launched a suite of generative AI cloud services known as the BioNeMo Cloud offering, part of NVIDIA AI Foundations. This service accelerates life sciences research, drug discovery, and protein engineering by providing pretrained AI models and enabling researchers to customize them using proprietary data. The offering includes six new optimized, open-source models, such as AlphaFold2 for protein structure determination and MoFlow for molecular optimization and small molecule generation.
In September 2022, Cadence Design Systems Inc., a US-based computational software company, acquired OpenEye Scientific Software Inc. for an undisclosed amount. This acquisition advanced Cadence's Intelligent System Design strategy by incorporating OpenEye's technologies and skilled team, thereby enhancing Cadence's core competency in computational software to include molecular modeling focused on life sciences. OpenEye Scientific Software Inc. is a US-based company specializing in computational molecular design.
Major companies operating in the structural biology and molecular modeling techniques market are Thermo Fisher Scientific Inc., Agilent Technologies Inc., Agile Molecule Inc., Bruker Corporation, Dassault Systemes SE, Illumina Inc., Chemical Computing Group ULC, Biomax Informatics AG, Horiba Ltd., Charles River Laboratories Inc., Adjuvance Technologies Inc., Novartis AG, QIAGEN N.V., Avanti Polar Lipids Inc., Acellera Ltd., Schrodinger Inc., OpenEye Scientific Software Inc., BioSolveIT GmbH, Optibrium Ltd., Simulations Plus Inc., Certara L.P., Genedata AG, Inte:Ligand GmbH, Molecular Networks GmbH, Molecular Discovery Ltd., Cresset Group Ltd., Biotherapeutics Inc., Biovista Inc., Collaborative Drug Discovery Inc., Dotmatics Ltd., Insilico Biotechnology AG, Leadscope Inc.
North America was the largest region in the structural biology and molecular modelling techniques market in 2024. The regions covered in the structural biology and molecular modeling techniques market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
The countries covered in the structural biology and molecular modeling techniques market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The structural biology and molecular modeling techniques market includes revenues earned by entities by using techniques such as homology modeling, threading, molecular dynamics cryo-electron microscopy (cryo-EM), nuclear magnetic resonance spectroscopy of proteins (NMR), and electron paramagnetic resonance (EPR). The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Structural Biology And Molecular Modeling Techniques Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on structural biology and molecular modeling techniques market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for structural biology and molecular modeling techniques ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The structural biology and molecular modeling techniques market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.