Transthyretin amyloidosis (ATTR) treatment refers to the medical treatments aimed at managing transthyretin amyloidosis, a progressive, life-threatening disease resulting from misfolded transthyretin proteins that form amyloid deposits in tissues. The condition arises due to familial or spontaneous mutations that destabilize transthyretin protein, causing aggregation and deposition of fibers in various tissues. This rare condition primarily affects the peripheral nerves, heart and other organs, with the two main forms being polyneuropathy (nerve damage) and cardiomyopathy (heart muscle disease).
The ATTR treatment market consists of sales by entities (organizations, sole traders and partnerships) of ATTR treatment drugs that are essential for controlling the disease's progression, managing symptoms and improving the quality of life for affected patients, as untreated cases can lead to significant morbidity and reduced life expectancy.
The global transthyretin amyloidosis treatment market was valued at $149.12 million in 2018 which grew till 2023 at a compound annual growth rate (CAGR) of more than 95.00%.
Increasing Adoption Of Personalized Medicine
The increasing adoption of personalized medicine propelled the growth of the ATTR treatment market. The adoption of personalized medicine has accelerated the development of novel therapeutics specifically designed to address the molecular causes of transthyretin amyloidosis (ATTR). These targeted treatments typically offer improved efficacy and reduced side effects compared to conventional therapies, making them more appealing to patients and driving increased market growth. For instance, in October 2022, according to the Personalized Medicine Coalition(PMC), a US-based organization that represents scientists, patients and providers, promoting the understanding and adoption of personalized medicine to benefit patients and the healthcare system, more than 75,000 genetic testing products and 300 personalized medicines were present on the market for people with multiple types of cancers, genetic rare diseases and a range of chronic and infectious diseases. Additionally, personalized medicines accounted for 34% of new drug approvals by the US Food and Drug Administration in 2022 and have accounted for at least 25% of approvals in each of the previous eight years. Therefore, the increasing adoption of personalized medicine supported the growth of the ATTR treatment market during the historic period.
The global ATTR treatment market is concentrated, with large players operating in the market. The top three competitors in the market made up to 100.00% of the total market in 2023.
Transthyretin Amyloidosis Treatment Global Market Opportunities And Strategies To 2033 from The Business Research Company provides the strategists; marketers and senior management with the critical information they need to assess the global transthyretin amyloidosis treatment market as it emerges from the COVID-19 shut down.
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Where is the largest and fastest-growing market for transthyretin amyloidosis treatment? How does the market relate to the overall economy; demography and other similar markets? What forces will shape the market going forward? The transthyretin amyloidosis treatment market global report from The Business Research Company answers all these questions and many more.
The report covers market characteristics; size and growth; segmentation; regional and country breakdowns; competitive landscape; market shares; trends and strategies for this market. It traces the market's history and forecasts market growth by geography. It places the market within the context of the wider transthyretin amyloidosis treatment market; and compares it with other markets.
The report covers the following chapters
- Introduction and Market Characteristics- Brief introduction to the segmentations covered in the market, definitions and explanations about the segment by type, by drug and by distribution channel.
- Key Trends- Highlights the major trends shaping the global market. This section also highlights likely future developments in the market.
- Macro-Economic Scenario - The report provides an analysis of the impact of the COVID-19 pandemic, impact of the Russia-Ukraine war and impact of rising inflation on global and regional markets, providing strategic insights for businesses in the transthyretin amyloidosis treatment market.
Global Market Size And Growth- Global historic (2018-2023) and forecast (2023-2028, 2033F) market values and drivers and restraints that support and control the growth of the market in the historic and forecast periods.
- Regional And Country Analysis - Historic (2018-2023) and forecast (2023-2028, 2033F) market values and growth and market share comparison by region and country.
- Market Segmentation - Contains the market values (2018-2023) (2023-2028, 2033F) and analysis for each segment by type, by drug and by distribution channel in the market. Historic (2018-2023) and forecast (2023-2028) and (2028-2033) market values and growth and market share comparison by region market.
- Regional Market Size and Growth - Regional market size (2023), historic (2018-2023) and forecast (2023-2028, 2033F) market values and growth and market share comparison of countries within the region. This report includes information on all the regions Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa and major countries within each region.
- Competitive Landscape - Details on the competitive landscape of the market, estimated market shares and company profiles of the leading players.
- Other Major And Innovative Companies- Details on the company profiles of other major and innovative companies in the market.
- Competitive Benchmarking- Briefs on the financials comparison between major players in the market.
- Competitive Dashboard- Briefs on competitive dashboard of major players.
- Key Mergers and Acquisitions- Information on recent mergers and acquisitions in the market is covered in the report. This section gives key financial details of mergers and acquisitions which have shaped the market in recent years.
- Market Opportunities And Strategies- Describes market opportunities and strategies based on findings of the research, with information on growth opportunities across countries, segments and strategies to be followed in those markets.
- Conclusions And Recommendations- This section includes recommendations for transthyretin amyloidosis treatment providers in terms of product/service offerings geographic expansion, marketing strategies and target groups.
- Appendix- This section includes details on the NAICS codes covered, abbreviations and currencies codes used in this report.
Markets Covered:
- 1) By Type: Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM); Transthyretin Amyloidosis With Polyneuropathy (ATTR-PN)
- 2) By Drug: Tafamidis; Patisiran; Inotersen; Other Drugs
- 3) By Distribution Channel: Hospital Pharmacies; Retail Pharmacies; Online Pharmacies
- Companies Mentioned: Pfizer Inc.; Alnylam Pharmaceuticals, Inc.; Ionis Pharmaceuticals, Inc.; BridgeBio Pharma, Inc.; Intellia Therapeutics Inc.
- Countries: China; Australia; India; Indonesia; Japan; South Korea; USA; Canada; Brazil; France; Germany; Italy; Spain; UK; Russia.
- Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
- Time-series: Five years historic and ten years forecast.
- Data: Ratios of market size and growth to related markets; GDP proportions; expenditure per capita; transthyretin amyloidosis treatment indicators comparison.
- Data segmentations: country and regional historic and forecast data; market share of competitors; market segments.
- Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.