Gene Switch Global Market Report 2024

Description

A gene switch is a molecular tool that can activate or deactivate genes or modulate their activity levels, allowing cells to adjust gene expression in response to various signals and environmental changes. Gene switches offer precise control over gene expression, facilitating targeted therapeutic treatments, advanced research endeavors, and enhanced biotechnology processes.

The primary types of gene switches include CAR T cell therapies, gene therapies, and other methods. CAR T cell therapies involve altering a patient's T cells, a type of immune cell, to express a receptor that targets cancer cells. The payment models for these therapies often include upfront payments and milestone payments, and they are used for managing treatment-related toxicity, regulating gene expression, and other therapeutic applications.

The gene switch market research report is one of a series of new reports from The Business Research Company that provides gene switch market statistics, including gene switch industry global market size, regional shares, competitors with a gene switch market share, detailed gene switch market segments, market trends, and opportunities, and any further data you may need to thrive in the gene switch industry. This gene switch market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The gene switch market size has grown rapidly in recent years. It will grow from $0.72 billion in 2023 to $0.82 billion in 2024 at a compound annual growth rate (CAGR) of 14.1%. The increase observed during the historical period can be linked to the expansion of gene-based clinical trials, advancements in regenerative medicine, growing public awareness of genetic technologies, broader research in functional genomics, and a rising demand for genetic testing services.

The gene switch market size is expected to see rapid growth in the next few years. It will grow to $1.39 billion in 2028 at a compound annual growth rate (CAGR) of 14.2%. The projected growth during the forecast period can be attributed to the growing need for personalized medicine, a higher prevalence of genetic disorders, an increased demand for targeted cancer therapies, global health initiatives, and the rising use of gene switches. Key trends expected in the forecast period include advancements in technology, CRISPR-based gene switches, AI integration, the adoption of gene switches for gene silencing, and epigenetic gene switches.

The growing prevalence of genetic disorders is anticipated to boost the gene switch market in the future. Genetic disorders arise from abnormalities in an individual's DNA, which can result from mutations, inherited genetic changes, or chromosomal anomalies. This increase in genetic disorders is largely due to greater awareness, enhanced diagnostic capabilities, better healthcare, and an aging population. Gene switches offer a significant advantage in managing these disorders by allowing precise control over gene expression, thereby fostering the development of targeted and effective treatments. For instance, in September 2023, the Cystic Fibrosis Trust, a UK-based national charity, reported an increase in registered cystic fibrosis patients in the UK from 10,908 in 2021 to 11,148 in 2022, marking a rise of 240 patients. Consequently, the increasing incidence of genetic disorders is fueling growth in the gene switch market.

The growing adoption of personalized medicine is expected to drive the expansion of the gene switch market. Personalized medicine customizes medical treatments based on individual characteristics, such as genetics or lifestyle, to enhance effectiveness and reduce adverse effects. The rise in personalized medicine is propelled by its potential for more effective treatments, advances in genomics, the increasing complexity of diseases, and supportive regulations. Gene switches play a key role in personalized medicine by providing precise control over gene expression, facilitating tailored therapeutic approaches based on individual genetic profiles. For example, the Personalized Medicine Coalition reported in February 2024 that the FDA approved 16 new personalized therapies for rare diseases in 2023, up from six in 2022. This growing adoption of personalized medicine is driving the gene switch market.

In January 2023, Autolus Therapeutics, a biopharmaceutical company based in the UK, partnered with Cabaletta Bio to incorporate Autolus' RQR8 safety switch system into cell therapies aimed at autoimmune diseases. This collaboration aims to enhance the safety and effectiveness of these therapies. Cabaletta Bio, a US-based biotechnology company, is involved in developing cell therapies.

Major companies operating in the gene switch market are Bristol-Myers Squibb Company, Novartis AG, Charles River Laboratories International Inc, bluebird bio Inc., Regenxbio Inc., Kite Pharma Inc., Genomatica Inc., Intellia Therapeutics Inc., Voyager Therapeutics Inc., Precigen Inc., Editas Medicine Inc., Cellectis SA, Autolus Therapeutics plc, aceRNA Technologies, Cartherics Pty Ltd, panCELLa Inc., Aptamer Group plc, Bellicum Pharmaceuticals Inc., Genocea Biosciences Inc., CRISPR Therapeutics AG

North America was the largest region in the gene switch market in 2023. The regions covered in the gene switch market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the gene switch market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The gene switch market consists of revenues earned by entities by providing services such as gene regulation services, custom gene synthesis, research and development services, consulting, and support. The market value includes the value of related goods sold by the service provider or included within the service offering. The gene switch market also includes sales of synthetic gene constructs, gene switch kits, regulatory proteins and small molecules, delivery systems, assay systems, software, and bioinformatics tools. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Gene Switch Global Market Report 2024 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on gene switch market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Gain a truly global perspective with the most comprehensive report available on this market covering 50+ geographies.
Understand how the market has been affected by the COVID-19 and how it is responding as the impact of the virus abates.
Assess the Russia - Ukraine war's impact on agriculture, energy and mineral commodity supply and its direct and indirect impact on the market.
Measure the impact of high global inflation on market growth.
Create regional and country strategies on the basis of local data and analysis.
Identify growth segments for investment.
Outperform competitors using forecast data and the drivers and trends shaping the market.
Understand customers based on the latest market shares.
Benchmark performance against key competitors.
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Where is the largest and fastest growing market for gene switch ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The gene switch market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The market characteristics section of the report defines and explains the market.
The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
The forecasts are made after considering the major factors currently impacting the market. These include:

The impact of sanctions, supply chain disruptions, and altered demand for goods and services due to the Russian Ukraine war, impacting various macro-economic factors and parameters in the Eastern European region and its subsequent effect on global markets.

The impact of higher inflation in many countries and the resulting spike in interest rates.

The continued but declining impact of COVID-19 on supply chains and consumption patterns.

Market segmentations break down the market into sub markets.
The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.

Scope

Markets Covered:1) By Type: CAR T Cell Therapies; Gene Therapies; Other Therapies
2) By Payment Model Employed: Upfront Payments; Milestone Payments
3) By Application Area: Management Of Treatment Related Toxicity; Regulation Of Gene Expression; Other Applications
Companies Mentioned: Bristol-Myers Squibb Company; Novartis AG; Charles River Laboratories International Inc; bluebird bio Inc.; Regenxbio Inc.
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita,
Data segmentations: country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery format: PDF, Word and Excel Data Dashboard.

Product Code: r20611

1. Executive Summary

2. Gene Switch Market Characteristics

3. Gene Switch Market Trends And Strategies

4. Gene Switch Market - Macro Economic Scenario

4.1. Impact Of High Inflation On The Market
4.2. Ukraine-Russia War Impact On The Market
4.3. COVID-19 Impact On The Market

5. Global Gene Switch Market Size and Growth

5.1. Global Gene Switch Market Drivers and Restraints
- 5.1.1. Drivers Of The Market
- 5.1.2. Restraints Of The Market
5.2. Global Gene Switch Historic Market Size and Growth, 2018 - 2023, Value ($ Billion)
5.3. Global Gene Switch Forecast Market Size and Growth, 2023 - 2028, 2033F, Value ($ Billion)

6. Gene Switch Market Segmentation

6.1. Global Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
CAR-T Cell Therapies
Gene Therapies
Other Therapies
6.2. Global Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
Upfront Payments
Milestone Payments
6.3. Global Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
Management Of Treatment Related Toxicity
Regulation Of Gene Expression
Other Applications

7. Gene Switch Market Regional And Country Analysis

7.1. Global Gene Switch Market, Split By Region, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
7.2. Global Gene Switch Market, Split By Country, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

8. Asia-Pacific Gene Switch Market

8.1. Asia-Pacific Gene Switch Market Overview
Region Information, Impact Of COVID-19, Market Information, Background Information, Government Initiatives, Regulations, Regulatory Bodies, Major Associations, Taxes Levied, Corporate Tax Structure, Investments, Major Companies
8.2. Asia-Pacific Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
8.3. Asia-Pacific Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
8.4. Asia-Pacific Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

9. China Gene Switch Market

9.1. China Gene Switch Market Overview
9.2. China Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F,$ Billion
9.3. China Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F,$ Billion
9.4. China Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F,$ Billion

10. India Gene Switch Market

10.1. India Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
10.2. India Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
10.3. India Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

11. Japan Gene Switch Market

11.1. Japan Gene Switch Market Overview
11.2. Japan Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
11.3. Japan Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
11.4. Japan Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

12. Australia Gene Switch Market

12.1. Australia Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
12.2. Australia Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
12.3. Australia Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

13. Indonesia Gene Switch Market

13.1. Indonesia Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
13.2. Indonesia Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
13.3. Indonesia Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

14. South Korea Gene Switch Market

14.1. South Korea Gene Switch Market Overview
14.2. South Korea Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
14.3. South Korea Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
14.4. South Korea Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

15. Western Europe Gene Switch Market

15.1. Western Europe Gene Switch Market Overview
15.2. Western Europe Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
15.3. Western Europe Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
15.4. Western Europe Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

16. UK Gene Switch Market

16.1. UK Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
16.2. UK Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
16.3. UK Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

17. Germany Gene Switch Market

17.1. Germany Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
17.2. Germany Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
17.3. Germany Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

18. France Gene Switch Market

18.1. France Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
18.2. France Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
18.3. France Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

19. Italy Gene Switch Market

19.1. Italy Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
19.2. Italy Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
19.3. Italy Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

20. Spain Gene Switch Market

20.1. Spain Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
20.2. Spain Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
20.3. Spain Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

21. Eastern Europe Gene Switch Market

21.1. Eastern Europe Gene Switch Market Overview
21.2. Eastern Europe Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
21.3. Eastern Europe Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
21.4. Eastern Europe Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

22. Russia Gene Switch Market

22.1. Russia Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
22.2. Russia Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
22.3. Russia Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

23. North America Gene Switch Market

23.1. North America Gene Switch Market Overview
23.2. North America Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
23.3. North America Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
23.4. North America Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

24. USA Gene Switch Market

24.1. USA Gene Switch Market Overview
24.2. USA Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
24.3. USA Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
24.4. USA Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

25. Canada Gene Switch Market

25.1. Canada Gene Switch Market Overview
25.2. Canada Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
25.3. Canada Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
25.4. Canada Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

26. South America Gene Switch Market

26.1. South America Gene Switch Market Overview
26.2. South America Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
26.3. South America Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
26.4. South America Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

27. Brazil Gene Switch Market

27.1. Brazil Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
27.2. Brazil Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
27.3. Brazil Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

28. Middle East Gene Switch Market

28.1. Middle East Gene Switch Market Overview
28.2. Middle East Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
28.3. Middle East Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
28.4. Middle East Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

29. Africa Gene Switch Market

29.1. Africa Gene Switch Market Overview
29.2. Africa Gene Switch Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
29.3. Africa Gene Switch Market, Segmentation By Payment Model Employed, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
29.4. Africa Gene Switch Market, Segmentation By Application Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

30. Gene Switch Market Competitive Landscape And Company Profiles

30.1. Gene Switch Market Competitive Landscape
30.2. Gene Switch Market Company Profiles
- 30.2.1. Bristol-Myers Squibb Company
  - 30.2.1.1. Overview
  - 30.2.1.2. Products and Services
  - 30.2.1.3. Strategy
  - 30.2.1.4. Financial Performance
- 30.2.2. Novartis AG
  - 30.2.2.1. Overview
  - 30.2.2.2. Products and Services
  - 30.2.2.3. Strategy
  - 30.2.2.4. Financial Performance
- 30.2.3. Charles River Laboratories International Inc
  - 30.2.3.1. Overview
  - 30.2.3.2. Products and Services
  - 30.2.3.3. Strategy
  - 30.2.3.4. Financial Performance
- 30.2.4. bluebird bio Inc.
  - 30.2.4.1. Overview
  - 30.2.4.2. Products and Services
  - 30.2.4.3. Strategy
  - 30.2.4.4. Financial Performance
- 30.2.5. Regenxbio Inc.
  - 30.2.5.1. Overview
  - 30.2.5.2. Products and Services
  - 30.2.5.3. Strategy
  - 30.2.5.4. Financial Performance

31. Gene Switch Market Other Major And Innovative Companies

31.1. Kite Pharma Inc.
31.2. Genomatica Inc.
31.3. Intellia Therapeutics Inc.
31.4. Voyager Therapeutics Inc.
31.5. Precigen Inc.
31.6. Editas Medicine Inc.
31.7. Cellectis SA
31.8. Autolus Therapeutics plc
31.9. aceRNA Technologies
31.10. Cartherics Pty Ltd
31.11. panCELLa Inc.
31.12. Aptamer Group plc
31.13. Bellicum Pharmaceuticals Inc.
31.14. Genocea Biosciences Inc.
31.15. CRISPR Therapeutics AG

32. Global Gene Switch Market Competitive Benchmarking

33. Global Gene Switch Market Competitive Dashboard

34. Key Mergers And Acquisitions In The Gene Switch Market

35. Gene Switch Market Future Outlook and Potential Analysis

35.1 Gene Switch Market In 2028 - Countries Offering Most New Opportunities
35.2 Gene Switch Market In 2028 - Segments Offering Most New Opportunities
35.3 Gene Switch Market In 2028 - Growth Strategies
- 35.3.1 Market Trend Based Strategies
- 35.3.2 Competitor Strategies

36. Appendix

36.1. Abbreviations
36.2. Currencies
36.3. Historic And Forecast Inflation Rates
36.4. Research Inquiries
36.5. The Business Research Company
36.6. Copyright And Disclaimer