PUBLISHER: The Business Research Company | PRODUCT CODE: 1527091
PUBLISHER: The Business Research Company | PRODUCT CODE: 1527091
PEGylated proteins are therapeutic proteins covalently bonded to polyethylene glycol (PEG), a process aimed at enhancing their pharmacokinetic properties and reducing immunogenicity, thus improving their therapeutic efficacy. These modified proteins find application in various medical fields, including drug delivery, diagnostics, and targeted therapy, offering prolonged action and potentially improving patient outcomes.
The primary products within the PEGylated proteins market include consumables and services, pegylation kits and reagents, monofunctional linear PEGs, bifunctional PEGs, and others. Consumables and services constitute a broad category encompassing products and services vital for PEGylated protein research and development, including kits, reagents, and various support services. The proteins themselves cover a range of types such as colony-stimulating factors, interferons, erythropoietin, recombinant factor VII, and others, serving diverse applications including cancer treatment, hepatitis, chronic kidney diseases, hemophilia, multiple sclerosis, gastrointestinal disorders, and more. End users of these products and services include pharmaceutical companies, biotechnology firms, contract research organizations, and academic research institutes.
The PEGylated proteins market research report is one of a series of new reports from The Business Research Company that provides PEGylated proteins market statistics, including the PEGylated proteins industry global market size, regional shares, competitors with the PEGylated proteins market share, detailed PEGylated proteins market segments, market trends, and opportunities, and any further data you may need to thrive in the PEGylated proteins industry. These PEGylated proteins market research reports deliver a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The PEGylated proteins market size has grown rapidly in recent years. It will grow from $1.29 billion in 2023 to $1.47 billion in 2024 at a compound annual growth rate (CAGR) of 13.7%. The growth observed during the historic period can be attributed to several factors, including enhanced therapeutic efficacy, a growing aging population, increased demand for long-acting formulations, improved drug safety profiles, and expanding applications, particularly in targeted drug delivery systems.
The PEGylated proteins market size is expected to see rapid growth in the next few years. It will grow to $2.47 billion in 2028 at a compound annual growth rate (CAGR) of 13.8%. The anticipated growth in the forecast period can be attributed to several factors, including increasing investment in rare diseases, the rapid expansion of the biopharmaceutical industry, the adoption of precision medicine approaches, heightened competition from biosimilar versions of biologic drugs, and the implementation of innovative market access strategies. Major trends expected in the forecast period include the integration of digital health technologies, the advancement of next-generation pegylation technologies, the development of customized formulations for precision medicine, a focus on combination therapies, and a shift towards patient-centric healthcare models.
The increasing prevalence of lifestyle diseases is set to drive the expansion of the PEGylated proteins market in the foreseeable future. Lifestyle diseases, which arise primarily from unhealthy habits and lifestyle choices such as poor diet, sedentary behavior, and smoking, are on the rise due to a combination of factors including reduced physical activity, consumption of processed foods, and heightened stress levels. PEGylated proteins play a crucial role in treating lifestyle diseases by improving the effectiveness, duration, and targeted delivery of therapeutic agents for conditions such as cardiovascular diseases, diabetes, and certain cancers. For example, the World Heart Federation (WHF) projected an increase in cardiovascular disease deaths from approximately 18.9 million in 2020 to over 22.2 million in 2030, as reported in October 2022. Additionally, the International Diabetes Federation (IDF) revealed in December 2021 that 537 million adults aged 20 to 79 years worldwide were diagnosed with diabetes, representing 1 in 10 individuals. Hence, the rising prevalence of lifestyle diseases is fueling the growth of the PEGylated proteins market.
Key players in the PEGylated proteins market are focusing on the development of innovative products such as PEGylation reagents to maintain a competitive edge. PEGylation reagents are chemical compounds that attach polyethylene glycol (PEG) chains to biomolecules, modifying their properties for various biomedical applications. For instance, Creative Enzymes, a US-based supplier of food additives and enzymes, introduced DSPE-PEG-Maleimide in May 2023 for targeted drug delivery. DSPE-PEG-Maleimide is a linear heterobifunctional PEGylation reagent containing DSPE phospholipids and maleimide, serving as a valuable self-assembly reagent for preparing PEGylated liposomes or micelles and providing thiol or cysteine reactive maleimide groups, commonly used in targeted drug delivery.
In February 2022, Merck KGaA, a pharmaceutical company based in Germany, acquired Exelead Inc. for $793 million to bolster its presence in the growing market for mRNA therapeutics. Exelead Inc., a US-based biopharmaceutical company specializing in GMP-certified PEGylation services for use in manufacturing process development, is expected to enhance Merck KGaA's capabilities in this sector.
Major companies operating in the PEGylated proteins market are Merck & Co. Inc., Bayer AG, Bristol Myers Squibb Company, AstraZeneca PLC, Roche Holding AG, Gilead Sciences Inc., Novo Nordisk A/S, Evonik Industries AG, Viatris Inc., Regeneron Pharmaceuticals Inc., Biogen Inc., Vertex Pharmaceuticals Incorporated, Lonza Group Ltd., Jazz Pharmaceuticals plc, Ipsen Pharma, Kyowa Kirin Co. Ltd., WuXi Biologics, BioMarin Pharmaceutical Inc., Ligand Pharmaceuticals Incorporated, Zydus Cadila, Enzon Pharmaceuticals Inc.
North America was the largest region in the PEGylated Proteins market in 2023. The regions covered in the PEGylated proteins market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
The countries covered in the PEGylated proteins market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The PEGylated proteins market consists of revenues earned by entities by providing services such as analytical services and contract manufacturing services for PEGylated protein. The market value includes the value of related goods sold by the service provider or included within the service offering. The PEGylated proteins market also includes sales of PEGylated enzymes, PEGylated antibodies, and PEGylated hormones. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
PEGylated Proteins Global Market Report 2024 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on pegylated proteins market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for pegylated proteins ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The pegylated proteins market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
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