Cell and gene therapy manufacturing services represent a pioneering sector within the biopharmaceutical industry, dedicated to the production of innovative treatments that modify the genetic material of individuals or use living cells to treat or prevent disease.
Cell therapy involves the transfer of cells with the relevant function into a patient, often aiming to restore or establish normal cell function, replacing damaged or absent cells. Gene therapy, on the other hand, involves altering the genetic material within a patient's cells to treat or prevent disease, offering potential cures for a wide range of genetic and acquired diseases.
The global cell and gene therapy manufacturing services market was valued at $3,860.06 million in 2018 which grew till 2023 at a compound annual growth rate (CAGR) of more than 12.0%.
Rising Autoimmune Diseases
During the historic period, an increasing incidence of autoimmune disease supported the growth of the cell and gene therapy manufacturing services market. Autoimmune disease refers to conditions in which the immune system mistakenly attacks the body's cells, tissues, or organs, leading to inflammation and dysfunction. The increasing incidence of autoimmune disorders is attributed to a combination of genetic predisposition, environmental factors and lifestyle changes. Cell and gene therapy manufacturing services are crucial in developing precision therapies for autoimmune diseases, providing targeted treatments to modulate the immune system with improved efficacy and safety.
For instance, in May 2023, according to the University of Oxford, a UK-based research university, about 10% of people have autoimmune diseases. Among them, 13% are women and 7% are men. This is higher than previous estimates, which were between 3% and 9%. Therefore, the increasing incidence of autoimmune disease positively impacted the growth of the cell and gene therapy manufacturing services market during the historic period.
Development Of Next-Generation CAR T Therapies
Cell and gene therapy manufacturing services companies are focusing on the development and recruitment of clinical trials for "off-the-shelf" allogeneic cell therapy to improve CAR T therapies. For instance, in October 2022, Allogene Therapeutics, a US-based clinical-stage biotechnology company, launched the CAR T Together initiative, a pioneering effort that unites prominent oncologists from esteemed research institutions nationwide. CAR T Together is working to improve CAR T therapies by creating allogeneic options. These come from donors, making them ready to use and easy to produce in large quantities.
The global cell and gene therapy manufacturing services market is highly concentrated, with a small number of large players dominating the market. The top ten competitors in the market made up 52.01% of the total market in 2022.
Cell And Gene Therapy Manufacturing Services Global Opportunities And Strategies To 2033 from The Business Research Company provides the strategists; marketers and senior management with the critical information they need to assess the global cell and gene therapy manufacturing services market as it emerges from the COVID-19 shut down.
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Where is the largest and fastest-growing market for cell and gene therapy manufacturing services? How does the market relate to the overall economy; demography and other similar markets? What forces will shape the market going forward? The cell and gene therapy manufacturing services market global report from The Business Research Company answers all these questions and many more.
The report covers market characteristics; size and growth; segmentation; regional and country breakdowns; competitive landscape; market shares; trends and strategies for this market. It traces the market's history and forecasts market growth by geography. It places the market within the context of the wider cell and gene therapy manufacturing services market; and compares it with other markets.
The report covers the following chapters
- Introduction and Market Characteristics- Brief introduction to the segmentations covered in the market, definitions and explanations about the segment by type, by indication, by application and by end-user.
- Key Trends- Highlights the major trends shaping the global market. This section also highlights likely future developments in the market.
- Macro-Economic Scenario- The report provides an analysis of the impact of the COVID-19 pandemic, impact of the Russia-Ukraine war and impact of rising inflation on global and regional markets, providing strategic insights for businesses in the cell and gene therapy manufacturing services market.
- Global Market Size And Growth- Global historic (2018-2023) and forecast (2023-2028, 2033F) market values and drivers and restraints that support and control the growth of the market in the historic and forecast periods.
- Regional And Country Analysis - Historic (2018-2023) and forecast (2023-2028, 2033F) market values and growth and market share comparison by region and country.
- Market Segmentation- Contains the market values (2018-2023) (2023-2028, 2033F) and analysis for each segment by type, by indication, by application and by end-user in the market. Historic (2018-2023) and forecast (2023-2028) and (2028-2033) market values and growth and market share comparison by region market.
- Regional Market Size and Growth- Regional market size (2023), historic (2018-2023) and forecast (2023-2028, 2033F) market values and growth and market share comparison of countries within the region. This report includes information on all the regions Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa and major countries within each region.
- Competitive Landscape- Details on the competitive landscape of the market, estimated market shares and company profiles of the leading players.
- Competitive Benchmarking - Briefs on the financials comparison between major players in the market.
- Competitive Dashboard - Briefs on competitive dashboard of major players.
- Key Mergers and Acquisitions- Information on recent mergers and acquisitions in the market is covered in the report. This section gives key financial details of mergers and acquisitions which have shaped the market in recent years.
- Market Opportunities And Strategies - Describes market opportunities and strategies based on findings of the research, with information on growth opportunities across countries, segments and strategies to be followed in those markets.
- Conclusions And Recommendations - This section includes recommendations for cell and gene therapy manufacturing services providers in terms of product/service offerings geographic expansion, marketing strategies and target groups.
- Appendix- This section includes details on the NAICS codes covered, abbreviations and currencies codes used in this report.
Markets Covered:
- 1) By Type: Gene Therapy; Cell Therapy
- 2) By Indication: Central Nervous System Disorders; Ophthalmology Diseases; Cardiovascular Diseases; Infectious Diseases; Orthopedic Diseases; Oncology Diseases; Metabolic Diseases; Other Diseases
- 3) By Application: Commercial Manufacturing; Clinical Manufacturing
- 4) By End-User: Academic and Research Institutes; Pharmaceutical and Biotechnology Companies; Other End-Users
- Companies Mentioned: Thermo Fisher Scientific, Inc.; Merck KGaA; F. Hoffmann-La Roche Ltd; Charles River Laboratories International Inc.; Catalent Inc.
- Countries: China; Australia; India; Indonesia; Japan; South Korea; USA; Canada; Brazil; France; Germany; Italy; Spain; UK; Russia.
- Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
- Time-series: Five years historic and ten years forecast.
- Data: Ratios of market size and growth to related markets; GDP proportions; expenditure per capita; cell and gene therapy manufacturing services indicators comparison.
- Data segmentations: country and regional historic and forecast data; market share of competitors; market segments.
- Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.