Proteases Global Market Report 2025

Description

Proteases encompass a diverse array of enzymes crucial for breaking down proteins. These enzymes play pivotal roles in facilitating digestion and alleviating protein-induced swelling and discomfort, aiding both bodily and skin-related processes.

The primary origins of proteases stem from animals, plants, and microbes. Animal-based proteases derive from animals and include pancreatic trypsin, chymotrypsin, pepsin, and renin. These enzymes are accessible in liquid and powder formats, finding applications across industries like food and beverage, healthcare, animal feed, among others.

The proteases market research report is one of a series of new reports from The Business Research Company that provides proteases market statistics, including proteases industry global market size, regional shares, competitors with a proteases market share, detailed proteases market segments, market trends and opportunities, and any further data you may need to thrive in the proteases industry. This proteases market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The proteases market size has grown strongly in recent years. It will grow from $3.4 billion in 2024 to $3.63 billion in 2025 at a compound annual growth rate (CAGR) of 6.8%. The growth in the historic period can be attributed to industrial applications in food processing, enzyme replacement therapy, increasing demand in detergent industry, widespread use in pharmaceutical manufacturing, growing awareness of enzyme benefits, application in leather and textile industries, biofuel production.

The proteases market size is expected to see strong growth in the next few years. It will grow to $4.94 billion in 2029 at a compound annual growth rate (CAGR) of 8.0%. The growth in the forecast period can be attributed to rising demand for sustainable industrial practices, development of therapeutic enzymes, emergence of personalized medicine, application in cell culture processes, demand for enzymes in waste management, advancements in protease inhibitor research, use in novel therapeutic approaches. Major trends in the forecast period include technological integration, advancements in enzyme engineering, biological solutions in agriculture, specialty enzymes, enzyme replacement therapies, emerging markets, collaborations for research and development.

The increasing number of health-conscious consumers is anticipated to drive the growth of the proteases market in the future. Health-conscious consumers (HCCs) are individuals who lead a 'wellness-oriented' lifestyle and are concerned about their nutrition and the environment. These consumers are interested in healthier products that contain proteases, which support digestive health and promote weight management. For example, in July 2022, a report from Food Insight, a US-based non-profit organization, indicated that 52% of participants in the 2022 Food and Health Survey followed a specific diet or eating pattern, an increase from 39% in 2021. The most popular choices included clean eating (16%), mindful eating (14%), and calorie counting (13%). Therefore, the rising number of health-conscious consumers is expected to boost the demand for proteases.

An upsurge in the animal feed industry is poised to drive the proteases market's expansion. Proteases, pivotal as enzymatic supplements in animal feed formulations, significantly enhance protein digestion, contributing to optimal nutrient absorption in livestock. This advancement leads to improved feed efficiency and healthier animal growth. Notably, statistics from January 2023, indicating increased feed production in various regions including Latin America, North America, and Oceania, highlight the sector's growth. The remarkable rise, particularly in pet feed production globally, underscores the pivotal role of the animal feed industry in propelling the proteases market.

Product innovation is a significant trend gaining traction in the protease market. Major players in this sector are concentrating on developing new products to secure a competitive edge. For example, in January 2023, Selecta Biosciences, a US-based biotechnology firm, and Astellas Pharma, a Japan-based pharmaceutical company, announced a licensing and development agreement for Xork, an IgG protease enzyme. Through this agreement, Astellas acquired the exclusive global rights to develop, manufacture, and commercialize Xork, which has the potential to improve gene therapy delivery by targeting and cleaving IgG antibodies that might otherwise obstruct treatment.

Leading companies are forming collaborations and partnerships to enhance their market presence. A strategic business partnership typically involves a structured relationship between two or more companies, established through one or more agreements or contracts. For instance, in January 2023, Selecta Biosciences entered into a partnership with Astellas. This collaboration aims to license and develop an agreement for IdeXork (Xork) and to advance Astellas's extensive gene therapy portfolio through the Selecta Biosciences clinic. Astellas Pharma Inc. is a pharmaceutical company based in Japan.

In May 2022, Vertex Pharmaceuticals, a US-based biopharmaceutical company, acquired a portfolio of protease medicines from Catalyst Biosciences Inc. for $60 million. This acquisition enhances Vertex's product offerings in protease medicines and paves the way for future growth. Catalyst Biosciences Inc. is also a US-based biotechnology firm.

Major companies operating in the proteases market are Advanced Enzymes Technologies Limited, E.l. Du Pont de Nemours & Company, Amano Enzymes Inc., Biocatalysts Limited, Koninklijke DSM NV, Dyadic International Incorporated, Specialty Enzymes & Biotechnologies Company, Associated British Foods Plc., BASF SE, Rossari Biotech Limited, Nagase & Company Limited, Jiangsu Boli Bioproducts Company Limited, Creative Enzymes Inc., Kemin Industries Inc., AB Enzymes GmbH, Lallemand Inc., Novozymes A/S, Chr. Hansen Holdings A/S, International Flavors & Fragrances Inc., Enzyme Development Corporation, Enzyme Solutions Inc., Enzyme Supplies Limited, Genencor International Inc., Kerry Group PLC, Lumis Biotech Pvt. Ltd., Megazyme International Ireland Ltd., Roche Diagnostics GmbH, Sandoz International GmbH, Sunson Industry Group Co. Ltd., The Soufflet Group, Thermo Fisher Scientific Inc., VTR Bio-Tech Co. Ltd.

North America was the largest region in the proteases market share in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the proteases market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the proteases market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The proteases market consists of sales of glutamic, metalloproteases, cysteine, serine, threonine, and aspartic proteases. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Proteases Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on proteases market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

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Where is the largest and fastest growing market for proteases ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The proteases market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The market characteristics section of the report defines and explains the market.
The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
The forecasts are made after considering the major factors currently impacting the market. These include:

The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.

Market segmentations break down the market into sub markets.
The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.

Scope

Markets Covered:1) By Source: Animal; Plant; Microbial
2) By Form: Liquid; Powder
3) By Application: Food And Beverage; Healthcare; Animal Feed; Other Applications
Subsegments:
1) By Animal: Gastric Proteases; Pancreatic Proteases
2) By Plant: Papain; Bromelain; Ficin
3) By Microbial: Bacterial Proteases; Fungal Proteases
Companies Mentioned: Advanced Enzymes Technologies Limited; E.l. Du Pont de Nemours & Company; Amano Enzymes Inc.; Biocatalysts Limited; Koninklijke DSM NV
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita,
Data segmentations: country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery format: PDF, Word and Excel Data Dashboard.

Product Code: r22893

1. Executive Summary

2. Proteases Market Characteristics

3. Proteases Market Trends And Strategies

4. Proteases Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics And Covid And Recovery On The Market

5. Global Proteases Growth Analysis And Strategic Analysis Framework

5.1. Global Proteases PESTEL Analysis (Political, Social, Technological, Environmental and Legal Factors, Drivers and Restraints)
5.2. Analysis Of End Use Industries
5.3. Global Proteases Market Growth Rate Analysis
5.4. Global Proteases Historic Market Size and Growth, 2019 - 2024, Value ($ Billion)
5.5. Global Proteases Forecast Market Size and Growth, 2024 - 2029, 2034F, Value ($ Billion)
5.6. Global Proteases Total Addressable Market (TAM)

6. Proteases Market Segmentation

6.1. Global Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Animal
Plant
Microbial
6.2. Global Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Liquid
Powder
6.3. Global Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Food And Beverage
Healthcare
Animal Feed
Other Applications
6.4. Global Proteases Market, Sub-Segmentation Of Animal, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Gastric Proteases
Pancreatic Proteases
6.5. Global Proteases Market, Sub-Segmentation Of Plant, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Papain
Bromelain
Ficin
6.6. Global Proteases Market, Sub-Segmentation Of Microbial, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Bacterial Proteases
Fungal Proteases

7. Proteases Market Regional And Country Analysis

7.1. Global Proteases Market, Split By Region, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
7.2. Global Proteases Market, Split By Country, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

8. Asia-Pacific Proteases Market

8.1. Asia-Pacific Proteases Market Overview
Region Information, Market Information, Background Information, Government Initiatives, Regulations, Regulatory Bodies, Major Associations, Taxes Levied, Corporate Tax Structure, Investments, Major Companies
8.2. Asia-Pacific Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
8.3. Asia-Pacific Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
8.4. Asia-Pacific Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

9. China Proteases Market

9.1. China Proteases Market Overview
9.2. China Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
9.3. China Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
9.4. China Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion

10. India Proteases Market

10.1. India Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
10.2. India Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
10.3. India Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

11. Japan Proteases Market

11.1. Japan Proteases Market Overview
11.2. Japan Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11.3. Japan Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11.4. Japan Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

12. Australia Proteases Market

12.1. Australia Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12.2. Australia Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12.3. Australia Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

13. Indonesia Proteases Market

13.1. Indonesia Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13.2. Indonesia Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13.3. Indonesia Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

14. South Korea Proteases Market

14.1. South Korea Proteases Market Overview
14.2. South Korea Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14.3. South Korea Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14.4. South Korea Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

15. Western Europe Proteases Market

15.1. Western Europe Proteases Market Overview
15.2. Western Europe Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15.3. Western Europe Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15.4. Western Europe Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

16. UK Proteases Market

16.1. UK Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16.2. UK Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16.3. UK Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

17. Germany Proteases Market

17.1. Germany Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
17.2. Germany Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
17.3. Germany Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

18. France Proteases Market

18.1. France Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
18.2. France Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
18.3. France Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

19. Italy Proteases Market

19.1. Italy Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
19.2. Italy Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
19.3. Italy Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

20. Spain Proteases Market

20.1. Spain Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20.2. Spain Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20.3. Spain Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

21. Eastern Europe Proteases Market

21.1. Eastern Europe Proteases Market Overview
21.2. Eastern Europe Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21.3. Eastern Europe Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21.4. Eastern Europe Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

22. Russia Proteases Market

22.1. Russia Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22.2. Russia Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22.3. Russia Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

23. North America Proteases Market

23.1. North America Proteases Market Overview
23.2. North America Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23.3. North America Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23.4. North America Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

24. USA Proteases Market

24.1. USA Proteases Market Overview
24.2. USA Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24.3. USA Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24.4. USA Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

25. Canada Proteases Market

25.1. Canada Proteases Market Overview
25.2. Canada Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.3. Canada Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.4. Canada Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

26. South America Proteases Market

26.1. South America Proteases Market Overview
26.2. South America Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26.3. South America Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26.4. South America Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

27. Brazil Proteases Market

27.1. Brazil Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27.2. Brazil Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27.3. Brazil Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

28. Middle East Proteases Market

28.1. Middle East Proteases Market Overview
28.2. Middle East Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28.3. Middle East Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28.4. Middle East Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

29. Africa Proteases Market

29.1. Africa Proteases Market Overview
29.2. Africa Proteases Market, Segmentation By Source, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29.3. Africa Proteases Market, Segmentation By Form, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29.4. Africa Proteases Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion

30. Proteases Market Competitive Landscape And Company Profiles

30.1. Proteases Market Competitive Landscape
30.2. Proteases Market Company Profiles
- 30.2.1. Advanced Enzymes Technologies Limited Overview, Products and Services, Strategy and Financial Analysis
- 30.2.2. E.l. Du Pont de Nemours & Company Overview, Products and Services, Strategy and Financial Analysis
- 30.2.3. Amano Enzymes Inc. Overview, Products and Services, Strategy and Financial Analysis
- 30.2.4. Biocatalysts Limited Overview, Products and Services, Strategy and Financial Analysis
- 30.2.5. Koninklijke DSM NV Overview, Products and Services, Strategy and Financial Analysis

31. Proteases Market Other Major And Innovative Companies

31.1. Dyadic International Incorporated
31.2. Specialty Enzymes & Biotechnologies Company
31.3. Associated British Foods Plc.
31.4. BASF SE
31.5. Rossari Biotech Limited
31.6. Nagase & Company Limited
31.7. Jiangsu Boli Bioproducts Company Limited
31.8. Creative Enzymes Inc.
31.9. Kemin Industries Inc.
31.10. AB Enzymes GmbH
31.11. Lallemand Inc.
31.12. Novozymes A/S
31.13. Chr. Hansen Holdings A/S
31.14. International Flavors & Fragrances Inc.
31.15. Enzyme Development Corporation

32. Global Proteases Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Proteases Market

34. Recent Developments In The Proteases Market

35. Proteases Market High Potential Countries, Segments and Strategies

35.1 Proteases Market In 2029 - Countries Offering Most New Opportunities
35.2 Proteases Market In 2029 - Segments Offering Most New Opportunities
35.3 Proteases Market In 2029 - Growth Strategies
- 35.3.1 Market Trend Based Strategies
- 35.3.2 Competitor Strategies

36. Appendix

36.1. Abbreviations
36.2. Currencies
36.3. Historic And Forecast Inflation Rates
36.4. Research Inquiries
36.5. The Business Research Company
36.6. Copyright And Disclaimer