PUBLISHER: Stratistics Market Research Consulting | PRODUCT CODE: 1476384
PUBLISHER: Stratistics Market Research Consulting | PRODUCT CODE: 1476384
According to Stratistics MRC, the Global Idiopathic Thrombocytopenic Purpura Therapeutics Market is accounted for $649.1 million in 2023 and is expected to reach $1045.0 million by 2030 growing at a CAGR of 7.04% during the forecast period. Idiopathic Thrombocytopenic Purpura (ITP) is a disorder characterized by a low platelet count in the blood (thrombocytopenia) due to the immune system mistakenly attacking and destroying platelets. Platelets are crucial for blood clotting, and a reduced platelet count can lead to abnormal bleeding or bruising. Patients are at risk of bleeding complications, so therapies may include platelet transfusions or medications to promote clotting and prevent bleeding episodes.
According to WebMD LLC, in 2022, ITP affected adults at roughly 66 cases per 1,000,000 per year. Children's incidence is estimated to be 50 cases per 1,000,000 per year on average, and about 10 new instances of chronic refractory ITP are reported each year per million people.
Rising demand for combination therapies
The market is witnessing a surge in demand for combination therapies, driven by their enhanced efficacy and ability to target multiple pathways simultaneously. This trend is propelled by the growing understanding of the complex nature and the need for more comprehensive treatment approaches. Combination therapies offer synergistic benefits, improved patient outcomes, and are increasingly preferred by healthcare providers and patients alike, shaping the landscape of treatment strategies.
Side effects of treatments
Corticosteroids may cause weight gain, mood swings, and increased risk of infection. Immunoglobulins can lead to allergic reactions or headaches. Splenectomy poses risks of infection due to reduced immune function and increases the risk of blood clots. Monitoring for these side effects and managing them appropriately is crucial in the treatment of thrombocytopenic purpura. Thus, in the market, treatments like corticosteroids, immunoglobulins, and splenectomy can have side effects.
Advances in treatment options
Novel therapies such as thrombopoietin receptor agonists (TPO-RAs) have emerged as effective agents for increasing platelet counts in ITP patients. Additionally, immunomodulatory drugs like rituximab and fostamatinib have shown promise in managing refractory cases. These developments reflect a growing understanding of ITP's pathophysiology and highlight the evolving landscape of targeted therapies for this hematologic disorder. Hence, these are the factors driving the growth of the market.
High cost of treatment
Patients often struggle with the financial burden of therapies, including immunoglobulins, corticosteroids, and splenectomy. These expenses can deter individuals from seeking necessary medical care and adhering to treatment plans. Additionally, research and development costs for innovative therapies contribute to the overall high cost of managing thrombocytopenic purpura, posing a barrier to accessible healthcare for affected individuals.
The COVID-19 pandemic significantly impacted the Thrombocytopenic Purpura Therapeutics Market. Lockdowns and healthcare priorities diverted focus from non-emergency conditions, affecting diagnosis and treatment. Supply chain disruptions led to shortages of critical medications, impacting patient care and treatment outcomes. Clinical trials were also delayed, hindering the development of new therapies. However, increased awareness of healthcare preparedness and telemedicine adoption could drive innovation and resilience in managing Thrombocytopenic Purpura in the post-pandemic era.
The rituximab segment is expected to be the largest during the forecast period
The rituximab segment is expected to be the largest during the forecast period. Rituximab, a monoclonal antibody targeting CD20 on B cells, has emerged as a promising therapy for thrombocytopenic purpura (ITP). In the therapeutics market, its role lies in modulating immune response, particularly in refractory or relapsed cases where conventional treatments fail. Its efficacy in increasing platelet counts and reducing bleeding episodes has bolstered its adoption, contributing significantly to the evolving landscape of ITP management.
The ambulatory surgical centers segment is expected to have the highest CAGR during the forecast period
The ambulatory surgical centers segment is expected to have the highest CAGR during the forecast period. They play a crucial role in the market by providing specialized care and procedures such as platelet transfusions and splenectomies. These centers offer a convenient and efficient setting for patients to receive treatment, contributing to improved patient outcomes and satisfaction. With advanced technologies and skilled medical professionals,
North America is projected to hold the largest market share during the forecast period. The market in the region is characterized by a diverse range of treatment options, including corticosteroids, intravenous immunoglobulins, and thrombopoietin receptor agonists. This market is driven by increasing awareness, advancements in medical technology, and a growing patient population. Additionally, ongoing research and development efforts contribute to the expansion of treatment modalities and improved outcomes for individuals in the region.
Asia Pacific is projected to hold the highest CAGR over the forecast period. Awareness and its treatment options has increased among healthcare professionals and patients, leading to early diagnosis and treatment. Pharmaceutical companies are collaborating with healthcare providers and research institutions in the region to develop and commercialize new treatments. Continuous research and development efforts aimed at improving treatment efficacy and safety are expected to further drive market growth in the region.
Key players in the market
Some of the key players in Idiopathic Thrombocytopenic Purpura Therapeutics market include Novartis, Pfizer, Sanofi, Amgen Inc., Johnson & Johnson, Takeda Pharmaceutical Company, GlaxoSmithKline, AbbVie, Teva Pharmaceutical Industries, Merck & Co., Bayer, Vertex Pharmaceuticals, FUJIFILM Holdings Corporation, Olympus Corporation, F. Hoffmann-La Roche Ltd, Medtronic, Eli Lilly and Company, GrifolsBiologicals and Sun Pharmaceutical Industries Ltd.
In January 2020, Novartis in association with The ITP Support Association announced the launch of ITP Pocket Log, designed to help people manage and track their ITP on the move, which is available on Google Play and Apple App Store.
In January 2019, GrifolsBiologicals Inc. announced that it has entered into a license agreement with the US-based biotechnology company Rigel Pharmaceuticals to commercialize fostamatinib disodium hexahydrate in all potential future indications in Europe and Turkey.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.