PUBLISHER: Stratistics Market Research Consulting | PRODUCT CODE: 1250776
PUBLISHER: Stratistics Market Research Consulting | PRODUCT CODE: 1250776
According to Stratistics MRC, the Global Opioid Use Disorder (OUD) Market is accounted for $3.17 billion in 2022 and is expected to reach $6.79 billion by 2028 growing at a CAGR of 13.5% during the forecast period. Opioids are a class of medications that also relax muscles, lessen pain, and ease stress. To treat moderate to severe pain, doctors often prescribe drugs like hydrocodone, oxycodone, codeine, fentanyl, methadone, morphine, and other prescription opioids. It involves functional alterations to brain circuits associated to motivation, stress, self-control, and decision-making, and because those changes may persist for a long time after drug use has stopped, it is recognised as a brain condition.
Growing focus of government & non-government institutions to support expansion
The expansion of the business is being fuelled in part by the growing involvement of governmental and non-governmental organisations in raising awareness of opioid overdose and associated consequences. Several groups have expanded their efforts to combat the issue as a result of the sharp rise in the number of opioid addicts. In order to help patients and decrease the effects of opioid dependence, many countries have increased their efforts. For instance, Health and Human Services (HHS) announced financing for substance use treatment and prevention programmes in order to increase access to medication-assisted treatment for opioid use disorder and curb prescription drug abuse. It is predicted that similar programmes would motivate more people with opioid-related problems to seek treatment.
Adverse effects of OUD drugs
The market is expected to experience challenges throughout the forecast period due to the negative effects of the medications used to treat opioid addiction. These medications frequently cause muscle aches, nausea, vomiting, diarrhoea, bone or joint pain, respiratory problems, bladder pain, constipation, and cramping in the abdomen. In addition, in extreme instances of a medication reaction, the patient may also experience depression and other psychological issues. The U.S. FDA issued a warning due to the hazards involved with these medications, which has a negative effect on the drug class and decreases the use of medications for this type of treatment.
Increasing consideration of buprenorphine patches
An increase in demand for buprenorphine patch treatments has lately been observed in the market. These patches are regarded as an effective medication for the treatment of opioid use disorders. Transdermal patches have a number of traditional, self-administered benefits, including an easier drug administration mechanism and less pain. Also, these transdermal patches might be a viable substitute for patients who need 24/7 opioid medication for opioid use disorder. Also, it is predicted that during the forecast period, a growing number of new patients will contribute to the growth of the global market for opioid use disorder (OUD).
Effects withdrawal syndrome
Withdrawal syndrome, which develops when repeated exposure to a pharmaceutical stimulus is stopped, is linked to dependency. Patients should be warned not to stop using long-term opioids without first lowering their dosage. Substance use disorder's subcategory of dependency can show physical, psychological, or both signs and symptoms. Regardless of the type of opioid used, withdrawal symptoms usually begin around the time of dependence. The main issue with opioid use disorder is withdrawal. When compared to methadone, withdrawal from heroin might start as quickly as five hours following the last dose. Withdrawal symptoms that last for days or weeks are referred to as prolonged abstinence syndrome.
Due to demand, the coronavirus pandemic has a variety of effects on the pharmaceutical business, ranging from favourable to unfavourable. Because fewer people are visiting healthcare institutions like hospitals and clinics, there has been a detrimental effect on the demand for some medications. Furthermore, a handful of governments have implemented a rigorous nationwide lockdown in an effort to reduce the number of coronavirus cases. This has caused the flow of patients between hospital settings to drastically decrease. Moreover, the cancellation or delay of unnecessary medical treatments has had a detrimental effect on market expansion. However, throughout the pandemic, well-known companies operating in the market for opioid use disorders, including Indivior PLC, saw a general reduction in their product revenues. As a result of COVID-19-related disruptions including lockdowns, transportation problems, and others, sales have fallen down quickly. Thus, it is anticipated that the market for opioid use disorders will suffer a setback.
The buprenorphine segment is expected to be the largest during the forecast period
The buprenorphine segment is estimated to have a lucrative growth. The most frequently recommended medications for OUD are buprenorphine/naloxone sublingual pills, buprenorphine sublingual tablets, and brand-name Suboxone. Because to its outstanding clinical profile, Suboxone Film is the medication that doctors most frequently prescribe in the OUD market. The high acceptance of this medicine can be due to a number of variables, including its good formulary coverage, high efficacy in controlling addiction, low potential for abuse, and very minor adverse effects.
The parenteral segment is expected to have the highest CAGR during the forecast period
The parenteral segment is anticipated to witness the fastest CAGR growth during the forecast period, due to the availability of several OUD medications in parenteral form and a range of dosages. As a result, this method of drug administration continues to rule the world market.
Asia Pacific is projected to hold the largest market share during the forecast period owing to increasing awareness amongst the general population regarding OUD. Additionally, the substantial patient population base and the increasing healthcare spending in the region are likely to favour the growth of the market in the region.
North America is projected to have the highest CAGR over the forecast period. One of the major drivers behind North America's largest market share is the opioid epidemic that has ravaged the United States and Canada due to the governments are implementing a number of initiatives. For instance, the American government started a public awareness campaign to fight opioid addiction. Throughout the course of the projected year, new medications are also anticipated to enter the U.S. market, including Braeburn's CAM-2038-additional buprenorphine subcutaneous formulation for regular monthly injection.
Some of the key players profiled in the Opioid Use Disorder (OUD) Market include Alkermes, Titan Pharmaceuticals, Inc, Hikma Pharmaceuticals PLC, Indivior PLC, Mallinckrodt Pharmaceuticals, Camurus, Orexo AB, Viatris Inc, BioDelivery Sciences International Inc., Teva Pharmaceuticals Usa, Inc, Mylan, Azanta, Braeburn, Chiesi Pharmaceuticals, DiaMo Narcotics, MaynePharma Group, Knight Therapeutics, Dr. Reddy's Laboratories, Collegium Pharmaceutical, Inc and Buvidal.
In March 2022, Collegium Pharmaceutical, Inc. announced that it had completed the acquisition of BioDelivery Sciences International Inc.
In June 2020, Titan Pharmaceuticals, Inc. entered into a partnership with Indegene to establish a multichannel digital marketing program throughout the U.S. and further increase their competence in providing Probuphine implant 2016 for opioid addiction patients.
In February 2021, Orexo AB announced its collaboration with ApexB.io and Magellan Rx Management to further research the use of Modia. This product is a digital therapeutic designed for patients with Opioid Use Disorder.
In December 2020, Orexo AB entered into an exclusive agreement with Accord Healthcare for the commercialization of ZUBSOLV and naloxone sublingual tablets in Europe.
In February 2019, Dr. Reddy's Laboratories announced the re-launch of its buprenorphine and naloxone sublingual film after the company received a favourable ruling in patent litigation.
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