PUBLISHER: Orion Market Research | PRODUCT CODE: 1296892
PUBLISHER: Orion Market Research | PRODUCT CODE: 1296892
Global molecular cytogenetics market is estimated to grow at a CAGR of 8.5% during the forecast period. The major factors contributing to the growth of the market include a significant prevalence of Cancer and increasing demand for genetic testing tools. As per the World Health Organization (WHO), the global Cancer burden is estimated to have risen to 18.1 million new cases and 9.6 million mortality in 2018. 43.8 million persons were living with Cancer in 2018 and were diagnosed within the last 5 years. This rising prevalence of Cancer is attributed to the demand for molecular cytogenetic tools.
Fluorescence in-situ hybridization (FISH) study is a crucial tool for both diagnostics and clinical research, as well as diagnostics, in Cancer and Leukemia. FISH can be utilized to assess chromosomal abnormalities with fluorescent-labeled DNA probes that target specific DNA sequences. FISH-based tests and comparative genomic hybridization (CGH), and multicolor karyotyping, have been utilized in clinical applications. These tests allow the whole global scanning of genomic imbalances and the resolution of complex karyotypic aberrations. Cross-species array CGH analysis has been used in the identification of Cancer genes.
The clinical effect of FISH is crucial, primarily in the diagnosis, prognosis, and treatment decisions for hematological conditions, which facilitate the area of personalized medicine. Molecular cytogenetics enables to properly differentiate of Cancer-causing and normal cells, which in turn, is leading to its adoption in Cancer diagnostics. Further, the market has significant growth opportunities owing to the advent of next-generation sequencing (NGS) and increasing research on personalized medicines. However, certain factors restricting market growth include the high cost of instruments and unfavorable reimbursement policies for genomic tools.
The global molecular cytogenetics market is segmented based on its product, application, and technique. Based on product, the market is segmented into consumables, software & services, and instruments. Based on application, the market is categorized into cancer, genetic disorders, and personalized medicine. Further, based on technique, the market is segmented into fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH), and others. Among the product segments, the consumables segment is expected to hold a prominent market share due to the recurring demand for consumables in diagnostic procedures.
Fluorescence in situ hybridization (FISH) is one of the major techniques in molecular cytogenetics testing.
Molecular cytogenetic techniques mainly rely on FISH, which is based on the principle of complementary hybridization of labeled DNA or RNA probes with normal or abnormal nucleic acid sequences on metaphase chromosomes, interphase cells, or tissue sections. FISH takes us to a colorful chromosome world, which involves a fluorescently labeled DNA probe hybridized to a specific genomic segment of interest. FISH can detect small chromosomal rearrangements that cannot be detected by conventional cytogenetic techniques. The use of the FISH technique enhanced the interpretation of the numerical and complex chromosomal rearrangements, bridging the gap between conventional cytogenetics and molecular biology. Therefore, it is being significantly adopted technique in genome research and cancer diagnostics. In genome research, FISH enables researchers to map and visualize the genetic material in an individual's cells, including portions of genes or specific genes. This technique may be applied to understand a range of chromosomal abnormalities and other genetic mutations.
Regional Outlooks
The global molecular cytogenetics market is further segmented based on geography, including North America, Europe, Asia-Pacific, and the Rest of the World. The market can be analyzed for a particular region or country level as per the requirement. The Asia-Pacific region is projected to experience considerable growth in the molecular cytogenetics market due to rising healthcare expenditure and increasing awareness about personalized medicine in the region.
Global Molecular Cytogenetics Market Growth, by Region 2023-2030
Source: OMR Analysis