Protein Purification and Isolation Market by Product, Technique, Application, End User

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List of Tables

Protein Purification & Isolation Market Size, Share, Forecast, & Trends Analysis by Product (Instruments, Consumables), Technique (Ultrafiltration, Precipitation), Application (Drug Screening, Target Identification), End User-Global Forecast to 2030

The global protein purification & isolation market is projected to reach $15.04 billion by 2030 at a CAGR of 9.1% from 2023 to 2030.

Succeeding extensive secondary and primary research and in-depth analysis of the market scenario, the report comprises the analysis of key industry drivers, restraints, challenges, and opportunities. The growth of this market is driven by the growing need to identify new protein-based drug molecules, rising research in pharmaceutical & biotechnology, and technological advancements. However, the high cost of purification instruments and the lack of skilled professionals are restraining the market's growth.

Furthermore, increasing research in precision medicine, and rising government spending on R&D in pharmaceutical & biotechnology, are expected to offer significant market growth opportunities. However, the increase in research cost due to the integration of multiple devices for acquiring high-purity proteins are the major challenges to the market's growth.

The report offers a competitive landscape based on an extensive assessment of the product portfolio offerings, geographic presences, and key strategic developments adopted by leading market players in the industry over four years (2020-2023). The key players operating in the global protein purification & isolation market are Thermo Fisher Scientific Inc. (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Merck KGaA (Germany), QIAGEN N.V. (Germany), Danaher Corporation (U.S.), Agilent Technologies, Inc. (U.S.), Promega Corporation (U.S.), F. Hoffmann-La Roche Ltd (Switzerland), BioVision Inc. (U.S.), Norgen Biotek Corp. (Canada), and Sartorius AG (Germany).

Among all the products studied in this report in 2023, the consumables segment is expected to account for the largest share of the protein purification & isolation market. This segment is further divided into protein purification kits, reagents, prepacked columns, protein purification resins, magnetic beads, and other consumables. The large market share of this segment is mainly attributed to the recurring use of consumables for protein purification, and the focus of various end users, such as academic & medical research institutes, and pharmaceutical companies on developing biopharmaceuticals.

Among all the techniques studied in this report, in 2023, the chromatography segment is expected to account for the largest share of the protein purification & isolation market. Chromatography is one of the most accurate and sensitive protein isolation & purification techniques. The use of chromatography for protein purification ensures protein extraction at sufficient purity in a cost-effective way, owing to which the adoption of this technique is higher.

Among all the applications studied in this report, in 2023, the protein-protein interaction studies segment is expected to account for the largest share of the global protein purification & isolation market. The large market share of this segment is attributed to the advantages offered by the protein-protein interaction studies, which help in understanding the kinetic properties of enzymes, suppressing or inactivating the protein. This study also aids in creating new binding sites for small effector molecules on proteins, which are crucial for biopharmaceutical research and commercial production.

Among end user, the academic & research institutes segment is projected to register the highest CAGR over the forecast period. The rising adoption of advanced protein purification & isolation technologies and the availability of funding for academic & research institutes are driving the growth of this segment.

An in-depth analysis of the geographical scenario of the global protein purification & isolation market provides detailed qualitative and quantitative insights into the five major region (North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa), along with the coverage of major countries in each region. In 2023, North America is expected to account for the largest share of the protein purification & isolation market. The U.S. is expected to account for the largest share of the protein purification & isolation market in North America. The large share of this regional market is attributed to the high R&D investment by the public and private sectors in pharmaceutical & biotechnology industries, advanced healthcare infrastructure, high adoption of precision therapy, and the presence of key market players.

Scope of the Report:

Protein Purification & Isolation Market Assessment-by Product

Instruments
Consumables

Protein Purification Kits
Reagents
Prepacked Columns
Protein Purification Resins
Magnetic Beads
Tagged Magnetic Beads
Non-tagged Magnetic Beads
- Other Consumables
- Software

Note: Other consumables include plastic ware, filters, chromatography solvents, and standards for chromatography and electrophoresis.

Protein Purification & Isolation Market Assessment-by Technique

Ultrafiltration
Precipitation
Chromatography
- Liquid Chromatography
- Ion Exchange Chromatography
- Affinity Chromatography
Immobilized Metal Ion Chromatography (IMAC)
Immunoaffinity Chromatography (IAC)
Bead-based Chromatography
- Reversed-phase Chromatography (RPC)
- Hydrophobic Interaction Chromatography (HIC)
- Size-exclusion Chromatography (Gel Filtration)
Electrophoresis
- Gel Electrophoresis
- Isoelectric Focusing
- Capillary Electrophoresis
Western Blotting (Immunoblotting)
Dialysis and Diafiltration
Centrifugation
Other Techniques

Note: Other techniques include mass spectroscopy and enzyme-linked immunosorbent assay (ELISA).

Protein Purification & Isolation Market Assessment-by Application

Protein-protein Interaction Studies
Drug Screening
Target Identification
Protein Therapeutics
Disease Diagnostics and Monitoring
Other Applications

Note: Other applications include disease diagnostics and monitoring and biomarker discovery.

Protein Purification & Isolation Market Assessment-by End User

Academic & Research Institutes
Hospitals and Diagnostics Centers
Pharmaceutical and Biotechnology Companies
Contract Research Organizations (CROs)
Other End Users

Note: Other end users include food, cosmetic, and agriculture industries.

Protein Purification & Isolation Market Assessment-by Geography

North America
U.S.
Canada
Europe
Germany
France
U.K
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Rest of Asia-Pacific
Latin America
Brazil
Mexico
Rest of Latin America
Middle East & Africa

Product Code: MRHC - 104794

1. Introduction

1.1. Market Definition
1.2. Market Ecosystem
1.3. Currency
1.4. Key Stakeholders

2. Research Methodology

2.1. Research Process
2.2. Data Collection and Validation
- 2.2.1. Secondary Research
- 2.2.2. Primary Research
2.3. Market Assessment
- 2.3.1. Market Size Estimation
  - 2.3.1.1. Bottom-up Approach
  - 2.3.1.2. Top-down Approach
  - 2.3.1.3. Growth Forecast
- 2.3.2. Market Share Analysis
2.4. Assumptions for the Study
2.5. Limitations for the Study

3. Executive Summary

4. Market Insights

4.1. Introduction
4.2. Drivers
- 4.2.1. Growing Need to Identify New Protein-based Drug Molecules
- 4.2.2. Rising Research in Pharmaceutical and Biotechnology
- 4.2.3. Technological Advancements
4.3. Restraints
- 4.3.1. High Cost of Purification Instruments
- 4.3.2. Lack of Skilled Professionals
4.4. Opportunity
- 4.4.1. Rising Research in Precision Medicine
- 4.4.2. Rising Government Spending on R&D in Pharmaceutical and Biotechnology
4.5. Challenges
- 4.5.1. Increase in the Research Cost Due to the Need for Integration of Multiple Devices for Acquiring High-Purity Proteins
4.6. Regulatory Analysis
4.7. Pricing Analysis
4.8. Impact of COVID-19 on Global Protein Purification and Isolation Market

5. Global Protein Purification and Isolation Market, by Product

5.1. Introduction
5.2. Instruments
5.3. Consumables
- 5.3.1. Protein Purification Kits
- 5.3.2. Reagents
- 5.3.3. Prepacked Columns
- 5.3.4. Protein Purification Resins
- 5.3.5. Magnetic Beads
  - 5.3.5.1. Tagged Magnetic Beads
  - 5.3.5.2. Non-tagged Magnetic Beads
- 5.3.6. Other Consumables
5.4. Software

6. Global Protein Purification and Isolation Market, by Technique

6.1. Introduction
6.2. Ultrafiltration
6.3. Precipitation
6.4. Chromatography Techniques
- 6.4.1 Liquid Chromatography
- 6.4.2. Ion Exchange Chromatography
- 6.4.3. Affinity Chromatography
  - 6.4.3.1. Immobilized Metal Ion Chromatography (IMAC)
  - 6.4.3.2. Immunoaffinity Chromatography (IAC)
  - 6.4.3.3. Bead-based Chromatography
- 6.4.4. Reversed-phase Chromatography ( RPC)
- 6.4.5. Hydrophobic Interaction Chromatography (HIC)
- 6.4.6. Size-exclusion Chromatography (Gel Filtration)
6.5. Electrophoresis
- 6.5.1. Gel Electrophoresis
- 6.5.2. Isoelectric Focusing
- 6.5.3. Capillary Electrophoresis
6.6. Western Blotting (Immunoblotting)
6.7. Dialysis and Diafiltration
6.8. Centrifugation
6.9. Other Techniques

7. Global Protein Purification and Isolation Market, by Application

7.1. Introduction
7.2. Drug Screening
7.3. Protein-protein Interaction Studies
7.4. Target Identification
7.5. Protein Therapeutics
7.6. Other Application

8. Global Protein Purification and Isolation Market, by End User

8.1. Introduction
8.2. Academic & Research Institutes
8.3. Hospitals and Diagnostics Centers
8.4. Pharmaceutical and Biotechnology Companies
8.5. Contract Research Organizations (CROs)
8.6. Other End Users

9. Protein Purification and Isolation Market, by Geography

9.1. Introduction
9.2. North America
- 9.2.1. U. S.
- 9.2.2. Canada
9.3. Europe
- 9.3.1. Germany
- 9.3.2. France
- 9.3.3. U.K.
- 9.3.4. Italy
- 9.3.5. Spain
- 9.3.6. Rest of Europe
9.4. Asia-Pacific
- 9.4.1. China
- 9.4.2. Japan
- 9.4.3. India
- 9.4.4. Rest of Asia-Pacific
9.5. Latin America
- 9.5.1. Brazil
- 9.5.2. Mexico
- 9.5.3. Rest of Latin America
9.6. Middle East and Africa

10. Competitive Landscape

10.1. Introduction
10.2. Key Growth Strategies
10.3. Competitive Dashboard
- 10.3.1 Industry Leaders
- 10.3.2 Market Differentiators
- 10.3.3 Vanguards
- 10.3.4 Emerging Companies
10.4. Vendor Market Positioning
10.4. Market Share Analysis (2022)

11. Company Profiles (Business Overview, Financial Overview, Solutions Portfolio, and Strategic Developments)

11.1. Thermo Fisher Scientific Inc.
11.2. Bio-Rad Laboratories, Inc.
11.3. Merck KGaA
11.4. QIAGEN N.V.
11.5. Danaher Corporation
11.6. Agilent Technologies, Inc.
11.7. Promega Corporation
11.8. F. Hoffmann-La Roche Ltd
11.9. BioVision Inc.
11.10. Norgen Biotek Corporation
11.11 Sartorius AG

12. Appendix

12.1. Questionnaire
12.2. Available Customization