Benign Prostatic Hyperplasia (BPH) - Current Landscape & Epidemiology Forecast 2033

Currently, there are a number of drugs approved by the US FDA for benign Prostatic Hyperplasia. For instance, Tadalafil (Eli Lilly), a phosphodiesterase-5 (PDE5) inhibitor approved by the US Food and Drug Administration (FDA) in 2011 to treat benign prostatic hyperplasia (BPH), either alone or in combination with Erectile Dysfunction. Other approved therapies include Proscar (Merck); Avodart (GlaxoSmithKline); Jalyn (GlaxoSmithKline); the approved alpha-blockers include Hytrin (Abbvie), Cardura (Pfizer), Flomax (Astellas), Uroxatral (Sanofi), and Rapaflo (Allergen). Treatment options for benign prostatic hyperplasia may also include lifestyle changes, medications, minimally invasive procedures, and surgery.

Alpha-blockers, 5-alpha reductase inhibitors, and phosphodiesterase-5 inhibitors, among other BPH treatments, are used to treat BPH symptoms by relaxing the smooth bladder muscles or reducing excessive prostate growth. Urine can flow more easily when the bladder muscles are relaxed since this reduces the prostate's hold on the urethra. In contrast, prostate shrinking lessens the pressure the prostate places on the urethra, allowing urine to flow freely.

"BPH treatments are generally effective initially, but as the prostate continues to grow as people get older, there is the possibility of needing additional treatments down the line. TURP has been and probably still is the gold-standard treatment for BPH, but a lot of times, newer procedures can match or beat that effectiveness with fewer side effects and fewer problems."

Benign prostatic hyperplasia (BPH) is a medical condition causing enlargement of the prostate gland. It commonly occurs as men age. BPH is also known as benign prostatic hypertrophy and is a histological diagnosis characterized by the proliferation of cellular elements of the prostate. BPH is considered a normal part of the aging process in men and is hormonally dependent on the production of testosterone and dihydrotestosterone (DHT). It is estimated that 50% of men experience histopathological BPH by age 60. This number increases to 90% by the age of 85.

Benign Prostatic Hyperplasia-Epidemiology

The total prevalent cases of Benign Prostatic Hyperplasia in the G7 countries are projected to increase from 43 million in 2018 to XX million by 2033 with a CAGR of 0.8% for the study period (2018-2033). According to estimates, the United States accounted for the highest prevalence of Benign Prostatic Hyperplasia cases in 2018 which was 14 million cases and is projected to reach XX million cases by 2033 with a CAGR of 1.0 % for the study period. Benign prostatic hyperplasia (BPH) is differentiated as per the severity of the cases as in mild, moderate and severe cases. In 2018, there were 14 million mild; 22 million moderate and 6 million severe cases of the BPH. These cases are expected to increase to XX million mild cases, XX million moderate cases and XX million severe BPH cases in 2033 for the study period from 2018-2033.

Patients do not expect this sickness to improve with treatments because they believe that deteriorating urine symptoms are a natural part of ageing or because they believe that they are only a transitory symptom and do not seek medical help. Whether through industry-funded DTC (direct-to-consumer) marketing or a source that might be less "biased," extensive patient education is required. Men (and those who care for them) need to be aware that untreated BPH can negatively affect general health, perhaps leading to earlier consultation with medical professionals. At least 50% of BPH patients are treated by primary care doctors, who are limited to prescribing drugs to these men. Urologists could have a significant influence by encouraging general practitioners to make earlier referrals.

Report Highlights:

• Benign Prostatic Hyperplasia - Current Market Trends

• Benign Prostatic Hyperplasia - Current & Forecasted Cases across the G7 Countries

• Benign Prostatic Hyperplasia - Untapped Business Opportunities

• Benign Prostatic Hyperplasia - KOLs Insight