Chronic Refractory Cough Market by Drug Type, Distribution Channel

Description

List of Tables

[182 Pages Report] The Chronic Refractory Cough Market size was estimated at USD 5.57 billion in 2023 and expected to reach USD 5.88 billion in 2024, at a CAGR 5.88% to reach USD 8.32 billion by 2030.

The Chronic Refractory Cough (CRC) market involves addressing a persistent cough that remains unresponsive to traditional treatments for more than eight weeks. Rising incidences of chronic respiratory conditions such as asthma, COPD, and bronchitis naturally lead to an increase in cases of chronic refractory coughs. Improved healthcare infrastructure and heightened awareness about CRC have led more individuals to seek treatment for chronic coughs, thus expanding the market. Innovative therapeutic approaches and advancements in medical technologies that offer higher efficacy in treating or managing CRC are also critical growth drivers in the market. However, CRC can often be misdiagnosed or overlooked as its symptoms may resemble those of other less severe illnesses, which can impede effective treatment. Some current treatments available have significant side effects, which might deter patients, creating challenges for continuing with their prescribed therapies. Moreover, there is a substantial opportunity for growth through the development of new pharmaceutical formulations and advanced therapeutic devices designed specifically for CRC management. Integrating CRC management with telehealth platforms can enhance accessibility for patients struggling with this condition, facilitating continuous management without frequent hospital visits.

KEY MARKET STATISTICS
Base Year [2023]	USD 5.57 billion
Estimated Year [2024]	USD 5.88 billion
Forecast Year [2030]	USD 8.32 billion
CAGR (%)	5.88%

Regional Insights

In the Americas region, the U.S. and Canada represent a substantial market for the management of chronic refractory cough due to its advanced healthcare infrastructure and high awareness levels regarding respiratory conditions. Recent patents in the U.S. have focused on novel cough suppressant therapies and cough management devices, highlighting a trend toward technological integration in treatment. The EU market is guided by stringent regulations that drive the demand for highly effective and safe treatments. Consumer behavior in the EU is characterized by a preference for evidence-based therapies. In the Middle East, there is increasing awareness and healthcare expenditure concerning chronic diseases, including CRC. The Middle East region shows growing interest in specialized healthcare services and international collaborations for advanced treatment methods. Recent initiatives in the African region aim to improve healthcare infrastructure and accessibility, which may increase the demand for CRC management solutions in the long term. In the APAC region, China has seen rapid health infrastructure improvements, which extend to the management of chronic coughs. CRC treatment in Japan often involves cutting-edge technology and pharmaceuticals supported by government-backed healthcare policies. Japan's aging population also makes it a critical market for CRC management solutions. In India, the rising middle class and improvements in healthcare facilities are creating significant opportunities for CRC management.

Market Insights

Market Dynamics

The market dynamics represent an ever-changing landscape of the Chronic Refractory Cough Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.

Market Drivers
- Rising prevalence of chronic refractory cough
- Government support for awareness and early diagnosis

Market Restraints
- Potential risk of drug recall

Market Opportunities
- Increasing R&D initiatives toward effective drug development
- Collaborative drug development and improving healthcare expenditure

Market Challenges
- Side effects associated CRC treatment

Market Segmentation Analysis
- Drug Type: Exploring gabapentin for innovative treatments for chronic refractory cough with neuropathic links
- Distribution Channel: Increasing preference to online pharmacies for chronic refractory cough treatment

Market Disruption Analysis
Porter's Five Forces Analysis
Value Chain & Critical Path Analysis
Pricing Analysis
Technology Analysis
Patent Analysis
Trade Analysis
Regulatory Framework Analysis

FPNV Positioning Matrix

The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the Chronic Refractory Cough Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the Chronic Refractory Cough Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Recent Developments

Investment Surge in Novel Respiratory Therapeutics: Focus on Nocion Therapeutics' Development of Taplucanium for Chronic Refractory Cough

Nocion Therapeutics, based in Watertown, Massachusetts, has completed a USD 62 million Series B funding round to advance the development of their innovative drug, taplucanium. Nocion is pioneering a novel approach by targeting the nociceptors-sensory neurons that trigger pain, itching, or coughs-which are implicated in various conditions including chronic refractory cough, a difficult-to-treat condition characterized by a persistent cough without a clear underlying cause [Published On: 2024-03-04]

Trevi Therapeutics Launches Phase 2a RIVER Trial for Haduvio, Advancement in Refractory Chronic Cough Treatment

Trevi Therapeutics, Inc., a pioneering company in clinical-stage biopharmaceuticals, recently initiated the Phase 2a RIVER clinical trial to assess the efficacy of Haduvio (oral nalbuphine ER) in treating patients with refractory chronic cough (RCC). The RIVER trial, a rigorous double-blind, placebo-controlled study with a 2-period crossover design, aims to enroll approximately 60 participants who suffer from moderate to severe cough frequencies [Published On: 2023-11-02]

GSK PLC Finalizes Acquisition of BELLUS Health Inc. Health to Enhance Chronic Refractory Cough Treatment Portfolio

GSK PLC has acquired BELLUS Health Inc., integrating BELLUS Health Inc.'s promising drug candidate, camlipixant, a highly selective P2X3 antagonist into its respiratory therapy lineup. Camlipixant, now in phase III trials, targets the first line treatment of adult patients with refractory chronic cough. The transaction, endorsed by BELLUS Health Inc. shareholders to leverage GSK PLC's robust R&D, manufacturing, and commercialization capabilities to expedite the drug's market launch. [Published On: 2023-06-28]

Strategy Analysis & Recommendation

The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the Chronic Refractory Cough Market. This critical assessment involves a thorough analysis of the organization's resources, capabilities, and overall performance to identify its core strengths and areas for improvement.

Key Company Profiles

The report delves into recent significant developments in the Chronic Refractory Cough Market, highlighting leading vendors and their innovative profiles. These include Accord Healthcare Inc., Alitair Pharmaceuticals, Amneal Pharmaceuticals Inc., Apotex Inc., AstraZeneca PLC, Aurobindo Pharma Ltd, Bausch Health, Bayer AG, Cipla Inc., Dr Reddy's Laboratories Ltd., Glenmark Pharmaceuticals Ltd., GSK PLC, Hikma Pharmaceuticals PLC, Intas Pharmaceuticals Ltd., Mylan N.V. by Viatris Inc., NeRRe Therapeutics, Novartis AG, Pfizer Inc., Sienna Biotec, Strides Pharma, Sun Pharmaceutical Industries Ltd, Teva Pharmaceutical Industries Ltd., Torrent Pharmaceuticals Ltd., Unichem Laboratories Ltd. by Ipca Labs, and Zydus Pharmaceuticals USA Inc..

Market Segmentation & Coverage

This research report categorizes the Chronic Refractory Cough Market to forecast the revenues and analyze trends in each of the following sub-markets:

Drug Type
- Amitriptyline
- Gabapentin
- Pregabalin

Distribution Channel
- Drug Store
- Hospital Pharmacies
- Online Pharmacies

Region
- Americas
  - Argentina
  - Brazil
  - Canada
  - Mexico
  - United States
    - California
    - Florida
    - Illinois
    - New York
    - Ohio
    - Pennsylvania
    - Texas
- Asia-Pacific
  - Australia
  - China
  - India
  - Indonesia
  - Japan
  - Malaysia
  - Philippines
  - Singapore
  - South Korea
  - Taiwan
  - Thailand
  - Vietnam

Europe, Middle East & Africa
- Denmark
- Egypt
- Finland
- France
- Germany
- Israel
- Italy
- Netherlands
- Nigeria
- Norway
- Poland
- Qatar
- Russia
- Saudi Arabia
- South Africa
- Spain
- Sweden
- Switzerland
- Turkey
- United Arab Emirates
- United Kingdom

Product Code: MRR-9A2BA9536664

1. Preface

1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders

2. Research Methodology

2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update

3. Executive Summary

4. Market Overview

5. Market Insights

5.1. Market Dynamics
- 5.1.1. Drivers
  - 5.1.1.1. Rising prevalence of chronic refractory cough
  - 5.1.1.2. Government support for awareness and early diagnosis
- 5.1.2. Restraints
  - 5.1.2.1. Potential risk of drug recall
- 5.1.3. Opportunities
  - 5.1.3.1. Increasing R&D initiatives toward effective drug development
  - 5.1.3.2. Collaborative drug development and improving healthcare expenditure
- 5.1.4. Challenges
  - 5.1.4.1. Side effects associated CRC treatment
5.2. Market Segmentation Analysis
- 5.2.1. Drug Type: Exploring gabapentin for innovative treatments for chronic refractory cough with neuropathic links
- 5.2.2. Distribution Channel: Increasing preference to online pharmacies for chronic refractory cough treatment
5.3. Market Disruption Analysis
5.4. Porter's Five Forces Analysis
- 5.4.1. Threat of New Entrants
- 5.4.2. Threat of Substitutes
- 5.4.3. Bargaining Power of Customers
- 5.4.4. Bargaining Power of Suppliers
- 5.4.5. Industry Rivalry
5.5. Value Chain & Critical Path Analysis
5.6. Pricing Analysis
5.7. Technology Analysis
5.8. Patent Analysis
5.9. Trade Analysis
5.10. Regulatory Framework Analysis

6. Chronic Refractory Cough Market, by Drug Type

6.1. Introduction
6.2. Amitriptyline
6.3. Gabapentin
6.4. Pregabalin

7. Chronic Refractory Cough Market, by Distribution Channel

7.1. Introduction
7.2. Drug Store
7.3. Hospital Pharmacies
7.4. Online Pharmacies

8. Americas Chronic Refractory Cough Market

8.1. Introduction
8.2. Argentina
8.3. Brazil
8.4. Canada
8.5. Mexico
8.6. United States

9. Asia-Pacific Chronic Refractory Cough Market

9.1. Introduction
9.2. Australia
9.3. China
9.4. India
9.5. Indonesia
9.6. Japan
9.7. Malaysia
9.8. Philippines
9.9. Singapore
9.10. South Korea
9.11. Taiwan
9.12. Thailand
9.13. Vietnam

10. Europe, Middle East & Africa Chronic Refractory Cough Market

10.1. Introduction
10.2. Denmark
10.3. Egypt
10.4. Finland
10.5. France
10.6. Germany
10.7. Israel
10.8. Italy
10.9. Netherlands
10.10. Nigeria
10.11. Norway
10.12. Poland
10.13. Qatar
10.14. Russia
10.15. Saudi Arabia
10.16. South Africa
10.17. Spain
10.18. Sweden
10.19. Switzerland
10.20. Turkey
10.21. United Arab Emirates
10.22. United Kingdom

11. Competitive Landscape

11.1. Market Share Analysis, 2023
11.2. FPNV Positioning Matrix, 2023
11.3. Competitive Scenario Analysis
- 11.3.1. Investment Surge in Novel Respiratory Therapeutics: Focus on Nocion Therapeutics' Development of Taplucanium for Chronic Refractory Cough
- 11.3.2. Trevi Therapeutics Launches Phase 2a RIVER Trial for Haduvio, Advancement in Refractory Chronic Cough Treatment
- 11.3.3. GSK PLC Finalizes Acquisition of BELLUS Health Inc. Health to Enhance Chronic Refractory Cough Treatment Portfolio
11.4. Strategy Analysis & Recommendation

12. Competitive Portfolio

12.1. Key Company Profiles
12.2. Key Product Portfolio