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PUBLISHER: IMARC | PRODUCT CODE: 1702116
PUBLISHER: IMARC | PRODUCT CODE: 1702116
In-vivo CRO Market Report by Type (Rodent, Non-Rodent), GLP Type (Non-GLP, GLP Toxicology), Indication (Autoimmune/Inflammation Conditions, Pain Management, Oncology, CNS Conditions, Diabetes, Obesity, and Others), and Region 2025-2033
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The global in-vivo CRO market size reached USD 5.3 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 9.8 Billion by 2033, exhibiting a growth rate (CAGR) of 6.76% during 2025-2033. The growing prevalence of chronic diseases worldwide and the increasing R&D expenditure by pharmaceutical companies are propelling the market growth.
In-vivo contract research organizations (CROs) are institutions that conduct extensive biopharmaceutical research on a contractual basis. They support pharmaceutical and biotechnology companies in formulating effective drugs, vaccines, and medical devices by providing outsourcing services. As compared to in-vitro CRO, in-vivo CRO deals with the research performed within the living organism and conducts human clinical trials to assess the safety and efficacy of the drugs instead of organizing examinations on removed cells and tissues. They aid research institutions in managing complex medical testing, developing effective medications at minimal costs, and optimizing workflow by avoiding delays caused by hiring, fundraising, and clinical preparations. As a result, in-vivo CRO finds extensive application in pain management, oncology, and treating central nervous system (CNS) injuries and other disorders. Currently, they are bifurcated into rodent- and non-rodent-based types.
In-vivo CRO Market Trends:
The increasing prevalence of various cardiovascular ailments, especially amongst the geriatric population, and the growing need for effective medications and novel oncology-based therapies for diagnosis and treatment are primarily driving the market growth. Additionally, the rising demand for clinical-scale manufacturing of active pharmaceutical ingredients (APIs) by contract research, development, and manufacturing organizations (CRDMOs) and the shifting inclination toward biosimilars over format monoclonal antibodies are acting as other growth-inducing factors. Furthermore, the fueling health concerns have prompted biotechnology companies to engineer effective novel vaccines in collaboration with CRO, especially during the COVID-19 pandemic, which is contributing to the market growth. Moreover, the extensive utilization of in-vivo CRO to perform toxicology and pharmacokinetic studies during preclinical activities is impelling the market growth. Apart from this, the advent of bioequivalence, rapid growth in generics, ongoing patent expirations, and continuous research and development (R&D) activities to engineer personalized medicines are creating a positive outlook for the market.
Key Market Segmentation:
Breakup by Type:
- Rodent
- Rats
- Mice
- Others
- Non-Rodent
Breakup by GLP Type:
- Non-GLP
- In House
- Outsourcing
- GLP Toxicology
- In House
- Outsourcing
Breakup by Indication:
Autoimmune/Inflammation Conditions
Rheumatoid Arthritis
Multiple Sclerosis
Osteoarthritis
Irritable Bowel Syndrome
Others
Pain Management
Chronic Pain
Acute Pain
Oncology
Blood Cancer
Solid Tumor
Others
CNS Conditions
Epilepsy
Parkinson's Disease
Huntington's Disease
Stroke
Traumatic Brain Injury
ALS
Muscle Regeneration
Others
Diabetes
Obesity
Others
Breakup by Region:
- North America
- United States
- Canada
- Asia-Pacific
- China
- Japan
- India
- South Korea
- Australia
- Indonesia
- Others
- Europe
- Germany
- France
- United Kingdom
- Italy
- Spain
- Russia
- Others
- Latin America
- Brazil
- Mexico
- Others
- Middle East and Africa
Competitive Landscape:
The competitive landscape of the industry has also been examined along with the profiles of the key players being Charles River Laboratories International Inc., Evotec SE, ICON plc, Iris Pharma (Abionyx Pharma), Labcorp Drug Development (Laboratory Corporation of America Holdings), North American Science Associates LLC, Parexel International Corporation, Pharmaceutical Product Development Inc. (Thermo Fisher Scientific Inc.), Pronexus Analytical AB, Syneos Health and WuXi AppTec.
Key Questions Answered in This Report
- 1.What was the size of the global in-vivo CRO market in 2024?
- 2.What is the expected growth rate of the global in-vivo CRO market during 2025-2033?
- 3.What are the key factors driving the global in-vivo CRO market?
- 4.What has been the impact of COVID-19 on the global in-vivo CRO market?
- 5.What is the breakup of the global in-vivo CRO market based on the type?
- 6.What is the breakup of the global in-vivo CRO market based on the GLP type?
- 7.What is the breakup of the global in-vivo CRO market based on indication?
- 8.What are the key regions in the global in-vivo CRO market?
- 9.Who are the key players/companies in the global in-vivo CRO market?
Product Code: SR112025A6267
Table of Contents
1 Preface
2 Scope and Methodology
- 2.1 Objectives of the Study
- 2.2 Stakeholders
- 2.3 Data Sources
- 2.3.1 Primary Sources
- 2.3.2 Secondary Sources
- 2.4 Market Estimation
- 2.4.1 Bottom-Up Approach
- 2.4.2 Top-Down Approach
- 2.5 Forecasting Methodology
3 Executive Summary
4 Introduction
- 4.1 Overview
- 4.2 Key Industry Trends
5 Global In-vivo CRO Market
- 5.1 Market Overview
- 5.2 Market Performance
- 5.3 Impact of COVID-19
- 5.4 Market Forecast
6 Market Breakup by Type
- 6.1 Rodent
- 6.1.1 Market Trends
- 6.1.2 Key Segments
- 6.1.2.1 Rats
- 6.1.2.2 Mice
- 6.1.2.3 Others
- 6.1.3 Market Forecast
- 6.2 Non-Rodent
- 6.2.1 Market Trends
- 6.2.2 Market Forecast
7 Market Breakup by GLP Type
- 7.1 Non-GLP
- 7.1.1 Market Trends
- 7.1.2 Key Segments
- 7.1.2.1 In House
- 7.1.2.2 Outsourcing
- 7.1.3 Market Forecast
- 7.2 GLP Toxicology
- 7.2.1 Market Trends
- 7.2.2 Key Segments
- 7.2.2.1 In House
- 7.2.2.2 Outsourcing
- 7.2.3 Market Forecast
8 Market Breakup by Indication
- 8.1 Autoimmune/Inflammation Conditions
- 8.1.1 Market Trends
- 8.1.2 Key Segments
- 8.1.2.1 Rheumatoid Arthritis
- 8.1.2.2 Multiple Sclerosis
- 8.1.2.3 Osteoarthritis
- 8.1.2.4 Irritable Bowel Syndrome
- 8.1.2.5 Others
- 8.1.3 Market Forecast
- 8.2 Pain Management
- 8.2.1 Market Trends
- 8.2.2 Key Segments
- 8.2.2.1 Chronic Pain
- 8.2.2.2 Acute Pain
- 8.2.3 Market Forecast
- 8.3 Oncology
- 8.3.1 Market Trends
- 8.3.2 Key Segments
- 8.3.2.1 Blood Cancer
- 8.3.2.2 Solid Tumor
- 8.3.2.3 Others
- 8.3.3 Market Forecast
- 8.4 CNS Conditions
- 8.4.1 Market Trends
- 8.4.2 Key Segments
- 8.4.2.1 Epilepsy
- 8.4.2.2 Parkinson's Disease
- 8.4.2.3 Huntington's Disease
- 8.4.2.4 Stroke
- 8.4.2.5 Traumatic Brain Injury
- 8.4.2.6 ALS
- 8.4.2.7 Muscle Regeneration
- 8.4.2.8 Others
- 8.4.3 Market Forecast
- 8.5 Diabetes
- 8.5.1 Market Trends
- 8.5.2 Market Forecast
- 8.6 Obesity
- 8.6.1 Market Trends
- 8.6.2 Market Forecast
- 8.7 Others
- 8.7.1 Market Trends
- 8.7.2 Market Forecast
9 Market Breakup by Region
- 9.1 North America
- 9.1.1 United States
- 9.1.1.1 Market Trends
- 9.1.1.2 Market Forecast
- 9.1.2 Canada
- 9.1.2.1 Market Trends
- 9.1.2.2 Market Forecast
- 9.1.1 United States
- 9.2 Asia-Pacific
- 9.2.1 China
- 9.2.1.1 Market Trends
- 9.2.1.2 Market Forecast
- 9.2.2 Japan
- 9.2.2.1 Market Trends
- 9.2.2.2 Market Forecast
- 9.2.3 India
- 9.2.3.1 Market Trends
- 9.2.3.2 Market Forecast
- 9.2.4 South Korea
- 9.2.4.1 Market Trends
- 9.2.4.2 Market Forecast
- 9.2.5 Australia
- 9.2.5.1 Market Trends
- 9.2.5.2 Market Forecast
- 9.2.6 Indonesia
- 9.2.6.1 Market Trends
- 9.2.6.2 Market Forecast
- 9.2.7 Others
- 9.2.7.1 Market Trends
- 9.2.7.2 Market Forecast
- 9.2.1 China
- 9.3 Europe
- 9.3.1 Germany
- 9.3.1.1 Market Trends
- 9.3.1.2 Market Forecast
- 9.3.2 France
- 9.3.2.1 Market Trends
- 9.3.2.2 Market Forecast
- 9.3.3 United Kingdom
- 9.3.3.1 Market Trends
- 9.3.3.2 Market Forecast
- 9.3.4 Italy
- 9.3.4.1 Market Trends
- 9.3.4.2 Market Forecast
- 9.3.5 Spain
- 9.3.5.1 Market Trends
- 9.3.5.2 Market Forecast
- 9.3.6 Russia
- 9.3.6.1 Market Trends
- 9.3.6.2 Market Forecast
- 9.3.7 Others
- 9.3.7.1 Market Trends
- 9.3.7.2 Market Forecast
- 9.3.1 Germany
- 9.4 Latin America
- 9.4.1 Brazil
- 9.4.1.1 Market Trends
- 9.4.1.2 Market Forecast
- 9.4.2 Mexico
- 9.4.2.1 Market Trends
- 9.4.2.2 Market Forecast
- 9.4.3 Others
- 9.4.3.1 Market Trends
- 9.4.3.2 Market Forecast
- 9.4.1 Brazil
- 9.5 Middle East and Africa
- 9.5.1 Market Trends
- 9.5.2 Market Breakup by Country
- 9.5.3 Market Forecast
10 SWOT Analysis
- 10.1 Overview
- 10.2 Strengths
- 10.3 Weaknesses
- 10.4 Opportunities
- 10.5 Threats
11 Value Chain Analysis
12 Porters Five Forces Analysis
- 12.1 Overview
- 12.2 Bargaining Power of Buyers
- 12.3 Bargaining Power of Suppliers
- 12.4 Degree of Competition
- 12.5 Threat of New Entrants
- 12.6 Threat of Substitutes
13 Price Analysis
14 Competitive Landscape
- 14.1 Market Structure
- 14.2 Key Players
- 14.3 Profiles of Key Players
- 14.3.1 Charles River Laboratories International Inc.
- 14.3.1.1 Company Overview
- 14.3.1.2 Product Portfolio
- 14.3.1.3 Financials
- 14.3.1.4 SWOT Analysis
- 14.3.2 Evotec SE
- 14.3.2.1 Company Overview
- 14.3.2.2 Product Portfolio
- 14.3.2.3 Financials
- 14.3.2.4 SWOT Analysis
- 14.3.3 ICON plc
- 14.3.3.1 Company Overview
- 14.3.3.2 Product Portfolio
- 14.3.3.3 Financials
- 14.3.3.4 SWOT Analysis
- 14.3.4 Iris Pharma (ABIONYX Pharma)
- 14.3.4.1 Company Overview
- 14.3.4.2 Product Portfolio
- 14.3.5 Labcorp Drug Development (Laboratory Corporation of America Holdings)
- 14.3.5.1 Company Overview
- 14.3.5.2 Product Portfolio
- 14.3.5.3 SWOT Analysis
- 14.3.6 North American Science Associates LLC
- 14.3.6.1 Company Overview
- 14.3.6.2 Product Portfolio
- 14.3.7 Parexel International Corporation
- 14.3.7.1 Company Overview
- 14.3.7.2 Product Portfolio
- 14.3.7.3 SWOT Analysis
- 14.3.8 Pharmaceutical Product Development Inc. (Thermo Fisher Scientific Inc.)
- 14.3.8.1 Company Overview
- 14.3.8.2 Product Portfolio
- 14.3.9 Pronexus Analytical AB
- 14.3.9.1 Company Overview
- 14.3.9.2 Product Portfolio
- 14.3.10 Syneos Health
- 14.3.10.1 Company Overview
- 14.3.10.2 Product Portfolio
- 14.3.10.3 Financials
- 14.3.10.4 SWOT Analysis
- 14.3.11 WuXi AppTec
- 14.3.11.1 Company Overview
- 14.3.11.2 Product Portfolio
- 14.3.11.3 Financials
- 14.3.1 Charles River Laboratories International Inc.
Product Code: SR112025A6267
List of Figures
- Figure 1: Global: In-vivo CRO Market: Major Drivers and Challenges
- Figure 2: Global: In-vivo CRO Market: Sales Value (in Billion USD), 2019-2024
- Figure 3: Global: In-vivo CRO Market Forecast: Sales Value (in Billion USD), 2025-2033
- Figure 4: Global: In-vivo CRO Market: Breakup by Type (in %), 2024
- Figure 5: Global: In-vivo CRO Market: Breakup by GLP Type (in %), 2024
- Figure 6: Global: In-vivo CRO Market: Breakup by Indication (in %), 2024
- Figure 7: Global: In-vivo CRO Market: Breakup by Region (in %), 2024
- Figure 8: Global: In-vivo CRO (Rodent) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 9: Global: In-vivo CRO (Rodent) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 10: Global: In-vivo CRO (Non-Rodent) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 11: Global: In-vivo CRO (Non-Rodent) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 12: Global: In-vivo CRO (Non-GLP) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 13: Global: In-vivo CRO (Non-GLP) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 14: Global: In-vivo CRO (GLP Toxicology) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 15: Global: In-vivo CRO (GLP Toxicology) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 16: Global: In-vivo CRO (Autoimmune/Inflammation Conditions) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 17: Global: In-vivo CRO (Autoimmune/Inflammation Conditions) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 18: Global: In-vivo CRO (Pain Management) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 19: Global: In-vivo CRO (Pain Management) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 20: Global: In-vivo CRO (Oncology) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 21: Global: In-vivo CRO (Oncology) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 22: Global: In-vivo CRO (CNS Conditions) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 23: Global: In-vivo CRO (CNS Conditions) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 24: Global: In-vivo CRO (Diabetes) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 25: Global: In-vivo CRO (Diabetes) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 26: Global: In-vivo CRO (Obesity) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 27: Global: In-vivo CRO (Obesity) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 28: Global: In-vivo CRO (Other Indications) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 29: Global: In-vivo CRO (Other Indications) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 30: North America: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 31: North America: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 32: United States: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 33: United States: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 34: Canada: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 35: Canada: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 36: Asia-Pacific: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 37: Asia-Pacific: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 38: China: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 39: China: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 40: Japan: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 41: Japan: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 42: India: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 43: India: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 44: South Korea: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 45: South Korea: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 46: Australia: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 47: Australia: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 48: Indonesia: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 49: Indonesia: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 50: Others: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 51: Others: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 52: Europe: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 53: Europe: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 54: Germany: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 55: Germany: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 56: France: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 57: France: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 58: United Kingdom: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 59: United Kingdom: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 60: Italy: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 61: Italy: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 62: Spain: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 63: Spain: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 64: Russia: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 65: Russia: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 66: Others: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 67: Others: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 68: Latin America: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 69: Latin America: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 70: Brazil: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 71: Brazil: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 72: Mexico: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 73: Mexico: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 74: Others: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 75: Others: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 76: Middle East and Africa: In-vivo CRO Market: Sales Value (in Million USD), 2019 & 2024
- Figure 77: Middle East and Africa: In-vivo CRO Market: Breakup by Country (in %), 2024
- Figure 78: Middle East and Africa: In-vivo CRO Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 79: Global: In-vivo CRO Industry: SWOT Analysis
- Figure 80: Global: In-vivo CRO Industry: Value Chain Analysis
- Figure 81: Global: In-vivo CRO Industry: Porter's Five Forces Analysis
List of Tables
- Table 1: Global: In-vivo CRO Market: Key Industry Highlights, 2024 and 2033
- Table 2: Global: In-vivo CRO Market Forecast: Breakup by Type (in Million USD), 2025-2033
- Table 3: Global: In-vivo CRO Market Forecast: Breakup by GLP Type (in Million USD), 2025-2033
- Table 4: Global: In-vivo CRO Market Forecast: Breakup by Indication (in Million USD), 2025-2033
- Table 5: Global: In-vivo CRO Market Forecast: Breakup by Region (in Million USD), 2025-2033
- Table 6: Global: In-vivo CRO Market: Competitive Structure
- Table 7: Global: In-vivo CRO Market: Key Players
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