PUBLISHER: Grand View Research | PRODUCT CODE: 1553464
PUBLISHER: Grand View Research | PRODUCT CODE: 1553464
The global plasmid purification market size is anticipated to reach USD 3.69 billion by 2030 and is projected to grow at a CAGR of 11.60% from 2024 to 2030, according to a new report by Grand View Research, Inc. Rising acceptance of cell & gene therapy and growing demand for recombinant technology products are factors contributing to market growth. Moreover, technological advancements in plasmid purification further propel market growth.
Plasmids are crucial in gene therapy and genetic medicine. Their unique properties allow them to serve as effective vectors for delivering therapeutic genes into target cells. Plasmids function by introducing exogenous genes into specific cells to correct or replace defective genes responsible for diseases. Moreover, with the increasing acceptance and application of gene therapy for treating various diseases, there is a growing need for purified plasmid DNA. In gene therapy, plasmids serve as vectors for delivering therapeutic genes.
Researchers design plasmids to carry therapeutic genes, including normal copies of mutated genes, genes encoding proteins to combat disease, or RNA molecules like shRNA that can silence harmful genes. Plasmid purification is critical in the development and application of gene therapy. Contaminants such as chromosomal DNA, proteins, endotoxins, and residual bacterial components can interfere with the efficacy and safety of the therapeutic product. Thus, advancements in purification technologies enhance the yield and quality of plasmid DNA, facilitating the scalability of plasmid production, which is essential for meeting the increasing demands of gene therapy development.
The COVID-19 pandemic has significantly impacted the market growth. The increased demand for synthetic biology products, driven by the urgent need for COVID-19 vaccines and treatments, has accelerated research and development (R&D) in cloning technology. This surge in R&D activities in synthetic biology has led to increased funding and investment in companies involved in vaccine development, diagnostics, and therapeutic research. Moreover, despite the challenges posed by the pandemic, the market is expected to continue growing steadily due to the increasing adoption of novel technologies, the rising demand for gene therapies, and ongoing advancements in genetic engineering.
However, one of the primary concerns of the market is the ethical constraints related to the use of recombinant DNA technology is the misuse of gene cloning and synthesis technology in the creation of harmful pathogens through synthetic biology techniques to develop bioweapons. Improper handling or disposal of synthetic DNA and plasmids could lead to environmental contamination. Engineered organisms released into the environment could have ecological consequences.