PUBLISHER: Grand View Research | PRODUCT CODE: 1493374
PUBLISHER: Grand View Research | PRODUCT CODE: 1493374
The global autoimmune hemolytic anemia treatment market is anticipated to reach USD 1.16 billion by 2030, growing at a CAGR of 6.5% from 2024 to 2030, according to a new report by Grand View Research, Inc. Increasing number of autoimmune hemolytic anemia (AIHA) cases worldwide, introduction of novel therapeutic drugs, increasing R&D activities, and favorable government initiatives are some of key factors driving the growth. For instance, the incidence of AIHA in France and Denmark is estimated at around 2.4 per 100,000 and 17.0 per 100,000 population, respectively.
Increasing research & activities to develop novel drugs for AIHA treatment is anticipated to drive the market expansion. Pharmaceutical companies and research institutes are actively involved in the development of novel and effective treatment options to manage AIHA. For instance, Zenas BioPharma is involved in the development of obexelimab for patients with warm autoimmune hemolytic anemia(wAIHA). The drug is in phase 3 of clinical trials and is being evaluated for efficacy and safety in patients with wAIHA. Similarly, Novartis AG is conducting clinical trials to evaluate the safety and efficacy of Ianalumab (VAY736) in patients who failed at least one line of treatment for warm autoimmune hemolytic anemia.
Moreover, the increasing involvement of government institutes and favorable initiatives undertaken by regulatory bodies to improve healthcare services to manage rare diseases are expected to increase the introduction of effective therapeutic solutions in the coming years. For instance, in December 2019, the U.S. FDA granted orphan drug designation to nipocalimab for the treatment of wAIHA and in July 2019, the U.S. FDA granted fast track designation for nipocalimab for the same indication. Such special designations for investigating candidates are expected to speed up the clinical trials and approval process.
Key players are adopting various market strategies such as acquisition and new product development to strengthen their market position. For instance, in September 2023, Bristol Myers Squibb acquired Asian regional market rights for bifunctional monoclonal antibody obexelimab from Zenas BioPharma, paying USD 50 million. Moreover, in June 2022, Rigel Pharmaceuticals, Inc. announced the results of phase 3 clinical trials of fostamatinib in patients with wAIHA, showing that patients treated with fostamatinib had a favorable durable hemoglobin response at the U.S., Canadian, Australian, and Western European trial sites.