Dual Chamber Syringes and Injectable Drug Reconstitution at the Point of Care

Dual chamber injection devices can be classified as either dual chamber syringes or dual chamber pen injectors. The Pen injector segment can be further divided into single-use dual chamber pen injectors and reusable dual chamber pen injectors. The latter relies on the use of a replaceable dual chamber cartridge that is inserted into the pen injector prior to use. While the use of dual chamber devices represents a cost premium for drug marketers relative to competing reconstitution methods such as vial adaptors, it also provides an opportunity for branding.

Because of stability and shelf life factors, therapeutic proteins must either be stored under special conditions or formulated to retain their efficacy from the time of manufacture until they are dispensed. Liquid protein drugs require refrigeration until dispensed - a distribution strategy referred to as the 'Cold Chain'. Alternatively, proteins can be formulated as powders. These lyophilized proteins must be reconstituted prior to injection.

Engineering Solutions to Patient Needs

The correlation between chronic conditions and the benefits of patient self-administration continues to influence therapeutic product decisions, managed care initiatives and regulatory actions. Drug injection device designs are increasingly being based on the results of human engineering inputs and patient preference research. Branding and packaging choices are more frequently being driven by data sources historically employed by consumer product marketers. For drug developers and device suppliers, the implications of these trends are influencing product development methodology and changing supply chain relationships. Decisions regarding as-supplied packaging that were once considered boilerplate have moved to the early stages of the development process.

What You Will Learn:

• What are the dynamics of the shifting landscape for injectable drug delivery and the market impact of new and evolving syringes and injectors by therapeutic indication?
• What are the market drivers influencing syringe and injector device designs, feature/functionality, product branding, competing technologies and commercial development?
• What are the key characteristics of the major injection device market segments and what is the impact of market demographics, and competing business strategies?
• What is the current market for syringe and injector demand by indication and therapy and what will it be in 2028?
• Who are the leading injection device companies, and what are their product development activities, business strategies, and corporate alliances and affiliations?
• What is the impact of economic, technology, and regulatory factors on injectable drug delivery demand?