PUBLISHER: GlobalData | PRODUCT CODE: 1511595
PUBLISHER: GlobalData | PRODUCT CODE: 1511595
Chronic kidney disease (CKD), or chronic renal disease (International Classification of Diseases 10th Revision [ICD-10] code = N18), is a condition characterized by a gradual loss of kidney function over time. This leads to the accumulation of excess fluid and waste in the body. In the early stages, CKD is a largely asymptomatic condition. As the disease progresses, symptoms worsen and eventually lead to kidney failure (Centers for Disease Control and Prevention, 2024a). Advanced chronic kidney disease can lead to dangerous levels of fluid, electrolytes, and waste accumulating in the body (Bentall, 2023). The glomerular filtration rate (GFR), a key measure of kidney function, is determined by the amount of creatinine in the blood. The Kidney Disease Improving Global Outcomes (KDIGO) classification system is considered to be the standard for GFR measurement and the diagnosis of CKD (Levin et al., 2013).
In the 7MM, the total prevalent cases of CKD are expected to increase from 110,299,913 cases in 2023 to 121,072,673 cases in 2033, at an annual growth rate (AGR) of 0.98%. In 2033, the US will have the highest number of total prevalent cases of CKD in the 7MM, with 45,087,454 cases, and Italy will have the fewest total prevalent cases of CKD with 3,778,783 cases. The diagnosed prevalent cases of CKD are expected to increase from 21,087,380 cases in 2023 to 22,975,558 cases in 2033, at an AGR of 0.90%. In 2033, the US will have the highest number of diagnosed prevalent cases of CKD in the 7MM, with 5,834,008 cases, and Italy will have the fewest diagnosed prevalent cases of CKD with 933,881 cases. GlobalData epidemiologists attribute the increase in the total and diagnosed prevalent cases of CKD to changes in population dynamics and the diagnosis rate in each market.