Global Particle Therapy Market - 2025 - 2033

The global particle therapy market reached US$ 1.33 billion in 2024 and is expected to reach US$ 2.58 billion by 2033, growing at a CAGR of 7.9% during the forecast period 2025-2033.

Particle therapy is an advanced form of radiation treatment that targets cancerous cells with charged particles such as protons, neutrons, and carbon ions. Unlike typical photon-based therapies that use X-rays, particle therapy uses the distinct physical features of charged particles to deliver radiation more precisely. This precision enables the greatest amount of radiation to be localized at the tumor site while minimizing exposure to adjacent healthy tissues, lowering the risk of side effects and long-term consequences associated with traditional radiation therapies.

The increasing demand for particle therapy is the driving factor that drives the market over the forecast period. The increasing number of cancer cases increases the demand for particle therapy since it is used in the treatment and management of cancer. For instance, according to the National Institute of Health, In 2023, the United States is projected to see 1,958,310 new cancer cases. Prostate cancer incidence reached 3% every year from 2014 to 2019, after two decades of reduction, resulting in an additional 99,000 new cases.

Market Dynamics: Drivers & Restraints

Increasing demand for particle therapy

The increasing demand for particle therapy is expected to be a significant factor in the growth of the global particle therapy market. The global particle therapy market is poised for significant expansion, owing mostly to the rising prevalence of cancer, technological advancements, recent launches and approvals, strategic partnerships, and increasing awareness among people. Particle therapy, which includes proton and heavy ion therapies, has several advantages over typical photon-based radiation treatments, including less harm to healthy tissues and fewer long-term negative effects. This precision in targeting malignancies improves patients' overall quality of life, resulting in an increasing preference for particle therapy among both healthcare practitioners and patients.

The rising global incidence of cancer has a substantial impact on the growing need for particle therapy. Cancer remains one of the top causes of sickness worldwide. For instance, According to the World Cancer Research Fund, the number of cancer cases in 2022, including non-melanoma skin cancer (NMSC), was 19,976,499. When NMSCs were eliminated, the global cancer case count was reduced to 18,741,966 in 2022. There were 9,566,825 males and 9,175,141 females. Furthermore, according to the IARC, there will be about 20 million new cancer cases in 2022 (including nonmelanoma skin cancers [NMSCs]). According to estimates, one in every five men and women will get cancer at some point in their lives. Lung cancer was the most often diagnosed cancer in 2022, accounting for about 2.5 million new cases, or one in every eight malignancies globally (12.4% of all cancers). Thus the need for effective treatment alternatives has never been stronger. This rising incidence highlights the critical need for improved therapeutic techniques such as particle therapy, which comprises proton and heavy ion therapies known for their precision in targeting tumors while causing minimal damage to adjacent healthy tissues.

Technological advancements have significantly improved the accessibility and efficacy of particle treatment. Recent innovations include the advent of compact and less expensive proton therapy devices, which made it possible for the installation of more treatment centers in diverse places. These innovations not only lower total treatment costs but also simplify the operational complexity involved with classic particle therapy systems. For instance, in October 2024, Jefferson Lab announced that it is collaborating with the Hampton University Proton Cancer Institute (HUPCI) and Leo Cancer Care to study the potential of proton therapy as a safer cancer treatment option. This collaboration intends to use new technology to improve the precision and effectiveness of proton therapy, which uses high-energy proton beams to target cancers while causing minimal damage to surrounding healthy tissues. This initiative is particularly significant since it aims to replace standard treatments that rely on radioactive isotopes like cobalt-60, which pose inherent radiological dangers.

High initial costs

Factors such as high initial costs are expected to hamper the global particle therapy market. Setting up a particle therapy center can cost more than USD 100 million, which includes expensive equipment such as cyclotrons or synchrotrons, specific shielding infrastructure, and the technologies required to ensure patient safety during treatment. For instance, according to the National Institute of Health, Particle treatment expenses vary from Euro 10,030 (c-ion: lung cancer) to Euro 39,610 (proton: head & neck malignancies). Many healthcare providers face a barrier to entry as a result of these significant capital commitments, particularly in underdeveloped countries with inadequate funding and healthcare budgets. As a result, the high financial cost of particle therapy limits its widespread acceptance and accessibility to individuals who could benefit from this innovative therapeutic technique.

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Segment Analysis

The global particle therapy market is segmented based on type, system, application, cancer type, end-user, and region.

Proton Therapy segment is expected to dominate the global particle therapy market share

The proton therapy segment is anticipated to dominate the global particle therapy market owing to its unique advantages, technological advancements, and increasing acceptance among healthcare providers and patients. Proton therapy uses charged particles, or protons, to deliver targeted radiation to malignant tumors while limiting damage to surrounding healthy tissues. This accuracy is especially useful for treating cancers near important organs, such as brain tumors or pediatric cancers, where conventional radiation therapies may represent a larger risk of collateral damage. As more people become aware of the benefits of proton therapy, demand for its utilization increases.

The increasing prevalence of cancer, as well as technological improvements that have made proton therapy more accessible and effective, are driving the segment's rise. Compact proton therapy devices and advanced imaging techniques have improved treatment delivery, resulting in more efficient patient management and better clinical outcomes. These technological advancements are critical in resolving the limits of standard photon treatment, hence strengthening proton therapy's market position.

Furthermore, the growing number of proton therapy centers worldwide contributes to the segment's dominance. Major investments and launches by healthcare organizations and governments have contributed to financing the establishment of new centers equipped with modern proton treatment devices. For instance, in February 2024, the University of Leeds initiated a trial supported by the National Institute for Health and Care Research (NIHR) and the Medical Research Council (MRC) to look into a possible treatment for brain cancer. A new clinical trial concentrating on proton beam therapy for brain cancer began in the United Kingdom, representing a significant leap in cancer treatment choices. This trial, called APPROACH (Analysis of Proton vs Photon Radiotherapy in Oligodendroglioma and Assessment of Cognitive Health), seeks to determine whether proton beam therapy can lessen long-term side effects when compared to regular photon radiotherapy. The experiment is aimed specifically at patients diagnosed with oligodendroglioma, a kind of brain cancer that affects roughly 350 people in the UK each year.

Geographical Analysis

North America is expected to hold a significant position in the global particle therapy market share

North America is anticipated to hold a significant portion of the global particle therapy market owing to the rising prevalence of cancer, technological advancements, recent product launches and approvals, strategic partnerships, and increasing awareness. The higher prevalence of cancer in North America also contributes to the increased demand for advanced treatment solutions. This alarming trend highlights the critical need for effective treatment alternatives, encouraging healthcare experts and patients to look into sophisticated medicines like particle therapy. As more patients become aware of the benefits of proton therapy, they are turning to this tailored treatment technique, which allows for more precise tumor targeting while avoiding damage to adjacent healthy tissues.

For instance, according to an article published by the National Institute of Health in 2024, the United States is projected to see 2,001,140 new cancer cases. North America's dominance in the particle therapy segment is due to technological breakthroughs. The emergence of small proton therapy systems has transformed the scene by making treatment more accessible and affordable. These systems require less physical space than traditional setups, allowing more hospitals and clinics to use proton therapy in their cancer treatment options. Furthermore, advances such as pencil-beam scanning and real-time imaging technology improve the precision of proton treatment, allowing practitioners to deliver targeted radiation more effectively while reducing damage to adjacent healthy tissues. This level of accuracy is especially useful for treating tumors near essential structures, such as those found in pediatric patients or brain cancers.

For instance, in December 2023, Nationwide Children's Hospital and The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) have announced the opening of a $100 million, 55,000-square-foot proton therapy center, the first treatment facility in central Ohio to provide this highly targeted form of radiation therapy for the treatment of complex tumors that cannot be removed surgically.

Asia Pacific is growing at the fastest pace in the global particle therapy market

One of the key drivers of this expansion is Asia Pacific's huge and expanding population, which contributes to an increased incidence of oncological disorders. As cancer incidence continues to increase across this diverse region, the need for advanced treatment modalities like particle therapy becomes increasingly critical.

For instance, according to the National Institute of Health, the estimated number of cancer cases in India in 2022 is 14,61,427 (crude rate: 100.4 per 100,000). In India, one in every nine people is likely to develop cancer over their lifetime. Males and females were more likely to acquire lung and breast cancers, respectively. This alarming trend underscores the urgent need for effective treatment options that can address the unique challenges posed by various types of cancer prevalent in the region.

Competitive Landscape

The major global players in the global particle therapy market include IBA Worldwide, Siemens Healthcare Private Limited, Hitachi High-Tech Corporation, Mevion Medical Systems, Provision Healthcare, Optivus Proton Therapy, Inc., Sumitomo Heavy Industries, Ltd., ProTom International, B dot Medical Inc., Atlas Copco Group among others.

Emerging Players

Panacea, Terapet, and P-Cure among others

Key Developments

• In September 2024, The Tata Memorial Centre (TMC) launched in-house research initiatives focused on maximizing the use of proton beam therapy for cancer treatment, marking a significant advancement in oncology care in India. This initiative coincides with the one-year anniversary of TMC's proton therapy facility, which was inaugurated to provide cutting-edge radiation treatment options for both pediatric and adult cancer patients. The facility at TMC is equipped with state-of-the-art technology, including the latest Pencil Beam Scanning (PBS) capabilities and Intensity Modulated Proton Therapy (IMPT).

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The global particle therapy market report delivers a detailed analysis with 60+ key tables, more than 50 visually impactful figures, and 176 pages of expert insights, providing a complete view of the market landscape.

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