Global Cervical Total Disc Replacement Device Market - 2023-2030

Market Overview

Cervical Total Disc Replacement Device Market size was valued at US$ XX million in 2021 and is estimated to reach US$ XX million by 2029, growing at a CAGR of 20.9% during the forecast period (2022-2029).

Cervical Total Disc Replacement (CTDR) device treats patients suffering from Degenerative Disc Disorders (DDD). Neck pain is the major cause of the development of DDD in the cervical spine region. Cervical disc replacement surgery is performed to treat DDD, where the degenerated disc is withdrawn surgically, and an artificial disc is implanted in the vertebra. This is a Minimal Invasive Surgery and results in quick recovery post-surgery, short hospital stays, and a downward revision surgery rate.

Market Dynamics

The global cervical total disc replacement device market is driven by increasing cases of cervical DDD, technological advancements, surge in geriatric population, increasing research and development activities to inprove the quality of device and rising healthcare expanditure.

Increasing benefits of cervical disc replacement devices drive market growth

The growing geriatric population and technological advancements in medical devices drive the market in the forecast period. As per the article published in Spine Journal in 2020, cervical disc replacement (CDR) is a motion-preserving surgical procedure for treating degenerative disorders. The rationale of CDR is to maintain cervical mobility while relieving pain, thereby reducing the risk of adjacent segment disease. Multiple in vitro studies have reported reduced intradiscal pressures in the adjacent level discs when using motion-preserving implants.

Furthermore, current cervical total disc replacement (TDR) designs incorporate various biomaterials, including polyethylene, stainless steel, titanium, and cobalt-chrome (CoCr). These materials are most important in their utilization as bearing surfaces, allowing for articular motion at the disc space. Long-term biological effects of implanted materials include wearing debris, host inflammatory immune reactions, and osteolysis resulting in implant failure.

The market players are offering cervical disc replacement devices. For instance, an artificial disc, such as the Prestige LP cervical disc produced by Medtronic, is placed between two adjacent cervical vertebrae to replace a diseased cervical disc. It is designed to maintain the distance between two adjacent cervical vertebrae. Two Prestige LP cervical discs replace two diseased cervical discs that are next to each other and require surgery.

The risk associated with cervical total disc replacement surgery will hamper the growth of the market

However, the cervical disc is inserted near important nerves and blood vessels. Healthcare professionals carefully find and protect these nerves and blood vessels, but there is a chance of injury to nerves or blood vessels at the time of the surgery. A little cut to a blood vessel can produce hemorrhage or even death. Injury to a nerve can cause long-term loss of movement (paralysis) or feeling.

COVID-19 Impact Analysis

The appearance of COVID-19 considerably impacted the global cervical total disc replacement device market. As per the article published in World Neurosurgery in July 2022, Elective surgery declined drastically during the second quarter of 2020. Patients undergoing surgery during the pandemic had a higher comorbidity burden, increasing total complication and mortality rates. The ramifications of canceling elective spine surgery were felt by both patients and spine surgeons in the U.S. and worldwide.

From a surgeon's perspective, the projected backlog of cases was estimated to take as long as 16 months to recover. Elective lumbar spine procedures decreased by 90% in the first two months of the pandemic. Telemedicine comprises two-thirds of outpatient spine appointments. The economic effect of canceling elective sp U.S9 ine surgery was also noticeable, given that cervical and lumbar fusion procedural volumes are consistently rising. These procedures rank among some of the most costly surgeries in the United States.

Segment Analysis

The radiculopathy segment is expected to grow at the fastest CAGR during the forecast period (2022-2029)

The radiculopathy segment accounts for the largest market share. Cervical total disc replacement is a routinely used treatment for radiculopathy due to degenerative disease of the cervical spine. The procedure originated to avoid complications seen with the traditional anterior cervical discectomy and fusion.

Cervical radiculopathy is a frequently encountered neurologic condition most often caused by encroachment of a cervical nerve root. It typically presents with neck and arm pain and sometimes sensory loss or loss of motor function in the affected nerve root distribution. The most common cause of cervical radiculopathy is degenerative features, including reduced disc height, osteophyte formation, and disc herniation.

Anterior cervical discectomy and fusion, either as individual implant surgical therapy or with further plating, has been the standard criterion for cervical radiculopathy for decades, and more than 100,000 patients receive this treatment in the US annually. Surgical treatment for cervical radiculopathy is growing in most countries and is projected to rise by more than 10% in the next 20 years.

Geographical Analysis

North America region holds the largest market share of the global cervical total disc replacement device market

North America dominates the cervical total disc replacement device market and is expected to show a parallel trend over the forecast period. The market is driven in the North American region by the increasing geriatric population, active key players, and product launches.

The key players apply market strategies such as acquisition and product launches to expand the business. For instance, in February 2021, NuVasive acquired Simplify Medical, which develops the Simplify Cervical Artificial Disc for cervical total disc replacement (cTDR), valued at $150m. With the acquisition, NuVasive can address all key parts of the cervical spine by providing inclusive, procedurally integrated solutions across anterior cervical discectomy and fusion (ACDF), posterior cervical fusion (PCF), and cTDR procedures.

Also, in April 2021, NuVasive, Inc. announced that the NuVasive Simplify Cervical Artificial Disc (Simplify Disc) received approval from the U.S. Food and Drug Administration for two-level cervical total disc replacement (cTDR). In a two-level FDA Investigational Device Exemption study, the Simplify Disc demonstrated clinical superiority at 24 months compared to anterior cervical discectomy and fusion (ACDF).

Competitive Landscape

The cervical total disc replacement device market is a moderately competitive presence of local and global companies. Some of the key players contributing to the market's growth are Zimmer Biomet Holdings, Medtronic Plc, Depuy Synthes, NuVasive Inc, Centinel Spine, Inc., Ranier Technology Limited, Stryker Corporation, AxioMed LLC, Orthofix International, Globus Medical Inc., among others. The major players are adopting several growth strategies, such as product launches, acquisitions, and collaborations, contributing to the growth of the cervical total disc replacement device market globally.

For instance,

In August 2021, Orthofix Medical launched the M6-C artificial cervical disc compared to anterior cervical discectomy and fusion for the therapy of contiguous two-level symptomatic cervical radiculopathy in the United States.

Zimmer Biomet Holdings

Overview:

Zimmer Biomet is a medical device company founded in 1927 to produce aluminum splints. The headquartered is in Warsaw, Indiana. Zimmer Biomet delivers personalized strategy and tailored solutions so you can manage the pain.

Product Portfolio:

Mobi-C Cervical Disc: The Mobi-C Cervical Disc is developed for cervical disc replacement to repair segmental motion and disc height. The components of Mobi-C include superior and inferior cobalt chromium molybdenum alloy endplates coated with plasma-sprayed titanium and hydroxyapatite coating and a polyethylene mobile bearing insert.

The global cervical total disc replacement device market report would provide access to approximately 60+ market data tables, 60+ figures, and in the range of 200+ (approximate) pages.