Dental Bone Graft Substitutes - Market Insights, Competitive Landscape, and Market Forecast - 2028

Dental Bone Graft Substitutes Market By Type (Xenograft, Allograft, Autograft, And Others), Mechanism (Osteoconduction, Osteoinduction, Osteogenesis, And Osteopromotion), End-Users (Hospitals, Dental Clinics, And Others), and geography is expected to grow at a steady CAGR forecast till 2028 owing to the increasing number of dental diseases and innovations in product development across the globe.

The global dental bone graft substitutes market is estimated to grow at a CAGR of 6.87% during the forecast period from 2023 to 2028. The demand for dental bone graft substitutes is primarily being boosted by the incidence of bone diseases such as bone infections and bone tumors and the growing number of dental surgeries worldwide. Moreover, the rising demand for synthetic substitutes, growing dental medical tourism in developing countries, increasing demand for aesthetic surgeries, surging number of product approvals, and innovation in product development among others are thereby contributed to the overall growth of the dental bone graft substitutes market during the forecast period from 2023-2028.

Dental Bone Graft Substitutes Market Dynamics:

As per the data provided by the World Health Organization (WHO) 2022, oral diseases affected nearly 3.5 billion people and over 530 million children suffered from caries of their primary teeth, in 2022, globally.

According to the American Dental Association report 2019, around 95% to 98% success rate has been reported for implant surgeries in 2019, across the United States. As per the same source, around 5 million implant procedures are performed in the US every year.

Bone grafting before implant placement helps to maintain the existing jaw and increases the chances of successful implant surgery. Thus, the increasing prevalence of bone diseases and surgeries across the different regions of the globe will increase the demand for bone graft substitutes, thereby propelling the overall market.

Further, the use of biocompatible and synthetic dental grafts is a growth-propelling factor for the market during the forecast period. Tricalcium phosphate (TCP) is mostly used as a synthetic scaffold in dentistry. It provides higher osteoconductivity as compared to allografts.

Additionally, the strategic initiatives taken by the market players are also propelling the growth of the market. For instance, in April 2022, the Aspen Group and ACE Surgical Supply, one of the providers of bone regenerative products, signed a multi-year strategic partnership for dental bone grafting solutions.

Therefore, the above-mentioned factors will propel the dental bone graft substitutes market during the forecast period from 2023-2028.

However, the lack of adequate reimbursement policies, risks associated with autografts and allografts, and others may restrict the growth of the overall dental bone graft substitutes market.

Dental Bone Graft Substitutes Market Segment Analysis:

Dental Bone Graft Substitutes Market By Type (Xenograft, Allograft, Autograft, and Others), Mechanism (Osteoconduction, Osteoinduction, Osteogenesis, and Osteopromotion), End-Users (Hospitals, Dental Clinics, and Others), and Geography (North America, Europe, Asia-Pacific, and Rest of the World).

In the type segment of the dental bone graft substitutes market, the Xenograft category is expected to amass a significant revenue share in the year 2022. This can be ascribed to the advantages and applications associated with the segment. A xenograft is an organ transplant or a tissue graft to an individual of another species. Xenografts are obtained from pigs (porcine) or cows (bovine) and are prepared for implantation into the human body once thoroughly cleaned and sterilized. Deproteinized bovine bone is the most common source of xenograft materials in dentistry.

The use of xenograft tissue helps stimulate the formation of new bone tissue, resulting in a strong and stable foundation for dental implants or other restorations.

Moreover, xenograft tissue is biocompatible with human tissue, meaning that it does not trigger an immune response or other adverse reactions. The compatibility of xenograft tissue with human tissue is crucial for dental implant procedures. Additionally, xenograft tissue has been shown to have a high success rate in dental procedures, with low complication rates and excellent long-term results. The high success rate of xenograft tissue in dental procedures makes it an ideal choice for patients seeking dental implants, bone regeneration, or bone augmentation.

Xenograft tissue is a cost-effective alternative to other grafting materials, such as autografts or allografts, which are more expensive and require additional procedures for harvesting or processing. The affordability of xenograft tissue makes it an excellent choice for patients seeking dental implant procedures or other restorations.

A few commercially available xenografts are Bio-Oss, Bio-Oss Collagen, and Pepgen-P15, among others.

Further, increasing product launches, approvals, and other strategic activities will also propel the demand for xenograft in the upcoming years. For instance, in March 2022, Fredun Pharmaceuticals Limited received approval to manufacture Xenografts for various dental and orthopedic surgical appliances from the Central Drugs Standard Control Organization (CDSCO), India.

Therefore, owing to the above-mentioned factors, the xenograft category is expected to register significant growth, thereby driving the growth of the overall dental bone graft substitutes market during the forecast period.

North America is expected to dominate the overall Dental Bone Graft Substitutes Market:

Among all the regions, North America is estimated to account for the largest share of the dental bone graft substitutes market in the year 2022. Owing to the significance of key growth factors such as increasing dental diseases, the increasing number of dental implant surgeries, high disposable income, sophisticated healthcare infrastructure, regulatory approval for new products, high awareness about the biomaterial-based dental bone graft substitutes, presence of key players, increasing product development activities, and others, the market for dental bone graft substitutes is expected to witness prosperity in the region during the forecast period 2022-2028.

The Centers for Disease Control and Prevention (CDC) 2021, stated that 1 in 4 adults between 20-64 years of age suffer from at least one cavity, and almost 57% of adolescents aged 12-19 have had a hole in their permanent teeth, in 2021, in the United States.

The same source in 202 data also concluded that more than 1 in 4 (26%) adults had untreated tooth decay and nearly half (46%) of all adults aged 30 years or older showed signs of gum disease and severe gum disease affected about 9% of adults in the United States, in 2020.

Further, the increasing approvals by the US FDA, increasing product launches in the market, and other strategic approvals will also impact the market of dental bone graft substitutes in the upcoming years. For instance, in August 2023, RevBio, Inc., received approval from the U.S. Food and Drug Administration to start a 20-patient clinical trial to examine the safety and efficacy of a more rapidly replaced, pH-modified porous formulation of the company's bone adhesive biomaterial called Tetranite® to immediately stabilize dental implants following tooth extractions. This new formulation has shown evidence of a more biologically active bone substitution.

Also, in January 2021, Dentsply Sirona acquired Datum Dental Ltd., known for innovative dental regeneration products. With this acquisition, Dentsply Sirona promotes the complete OSSIX portfolio, including OSSIX Plus, OSSIX Volumax, and OSSIX Bone, in the United States, Canada, and several other countries.

Thus, the above-mentioned factors are likely to propel the growth of the dental bone graft substitutes market in the region during the forecast period from 2023-2028.

Dental Bone Graft Substitutes Market Key Players:

Some of the key market players operating in the dental bone graft substitutes market include: Dentsply Sirona, Medical Device Business Services, Inc., Institut Straumann AG, Medtronic, Zimmer Biomet, Geistlich Pharma AG, DentiumUSA, LifeNet Health, Collagen Matrix Inc., Halma plc, Botiss biomaterials GmbH, Wright Medical Group N.V., Biogennix, LLC, BioHorizons, RTI Surgical, Orthogen LLC, OSTEOGENICS BIOMEDICAL, Regenity, Ultradent Products Inc, AlloSource, and others.

Recent Developmental Activities in the Dental Bone Graft Substitutes Market:

• In March 2022, Biocomposites signed an agreement with Zimmer Biomet to distribute the new Genex Bone Graft Substitute. Genex Bone Graft Substitute is a biphasic composite of exceptional purity specifically formulated to balance osteoconductive scaffold strength and persistence in the body to enable the optimal remodeling of bone architecture.
• In September 2021, Neoss signed an agreement with Purgo Biologics and became a key partner and distributor of the Purgo Xenograft product range for dental implant solutions in the German, Swedish, and United Kingdom markets.
• In March 2019, BioHorizons acquired Intra-Lock to include the IntraSpin system in its portfolio for better penetration in the dental bone grafts market.

Key Takeaways from the Dental Bone Graft Substitutes Market Report Study:

• Market size analysis for current dental bone graft substitutes market size (2022), and market forecast for 5 years (2023-2028)
• Top key product/services/technology developments, mergers, acquisitions, partnerships, and joint ventures happened for the last 3 years
• Key companies dominating the global dental bone graft substitutes market.
• Various opportunities are available for the other competitors in the dental bone graft substitutes market space.
• What are the top-performing segments in 2022? How these segments will perform in 2028?
• Which are the top-performing regions and countries in the current dental bone graft substitutes market scenario?
• Which are the regions and countries where companies should have concentrated on opportunities for dental bone graft substitute market growth in the coming future?

Target Audience who can be benefited from this Dental Bone Graft Substitutes Market Report Study:

• Dental bone graft substitute product providers
• Research organizations and consulting companies
• Dental bone graft substitutes-related organizations, associations, forums, and other alliances
• Government and corporate offices
• Start-up companies, venture capitalists, and private equity firms
• Distributors and Traders dealing in dental bone graft substitutes
• Various End-users who want to know more about the dental bone graft substitute market and the latest technological developments in the dental bone graft substitute market.

Frequently Asked Questions for the Dental Bone Graft Substitutes Market:

1. What are dental bone graft substitutes?

• A bone graft is used to fix problematic joints or damaged ones, which helps grow bone around the implant. Bone grafting is performed before dental implants to restore missing teeth. Dentistry uses bone grafts as fillers and scaffolds to facilitate bone formation and promote wound healing.

2. What is the market for global dental bone graft substitutes?

• The global dental bone graft substitutes market is estimated to grow at a CAGR of 6.87% during the forecast period from 2023 to 2028.

3. What are the drivers for the global dental bone graft substitutes market?

• The demand for dental bone graft substitutes is primarily being boosted by the increasing use of bone grafts in density and a growing number of dental implant surgeries. Further, increasing accidents, injuries, and sports injuries, a growing elderly population prone to dental diseases, increasing dental medical tourism, technological advancements in dentistry, and others thereby contributing to the overall growth of the dental bone graft substitutes market during the forecast period from 2023-2028.

4. Who are the key players operating in the global dental bone graft substitutes market?

• Some of the key market players operating in the dental bone graft substitutes market include Dentsply Sirona, Medical Device Business Services, Inc., Institut Straumann AG, Medtronic, Zimmer Biomet, Geistlich Pharma AG, DentiumUSA, LifeNet Health, Collagen Matrix Inc., Halma plc, Botiss biomaterials GmbH, Wright Medical Group N.V., Biogennix, LLC, BioHorizons, RTI Surgical, Orthogen LLC, OSTEOGENICS BIOMEDICAL, Regenity, Ultradent Products Inc, AlloSource, and others.

5. Which region has the highest share in the dental bone graft substitutes market?

• North America is expected to dominate the overall dental bone graft substitutes market during the forecast period from 2023-2028. Owing to factors such as rising increasing dental diseases, the increasing number of dental implant surgeries, high disposable income, sophisticated healthcare infrastructure, regulatory approval for new products, and high awareness about biomaterial-based dental bone graft substitutes among others, the North American dental bone graft substitutes market is expected to growth in coming years.