DelveInsight's 'Seasonal Influenza - Market Insights, Epidemiology, and Market Forecast-2032' report delivers an in-depth understanding of the Seasonal Influenza, historical and forecasted epidemiology as well as the Seasonal Influenza market trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
The Seasonal Influenza market report provides current treatment practices, emerging drugs, and market share of individual therapies, current and forecasted 7MM Seasonal Influenza market size from 2019 to 2032. The Report also covers current Seasonal Influenza treatment practice, market drivers, market barriers, SWOT analysis, reimbursement and market access, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.
Geography Covered:
- The United States
- EU5 (Germany, France, Italy, Spain, and the United Kingdom)
- Japan
Study Period: 2019-2032.
Seasonal Influenza- Disease Understanding and Treatment Algorithm
Seasonal influenza is an acute viral infection that spreads easily from person to person, causing annual epidemics which peak during the winter in temperate regions of the world. There are four types of influenza viruses: influenza A, B, C, and D, but only influenza A and B viruses cause clinically important human diseases and seasonal epidemics.
Seasonal influenza is caused by a novel variant that exhibits antigenicity that is distinct from the past strains due to accumulated mutations. While seasonal influenza (flu) viruses are detected year-round in the United States, flu viruses are most common during the fall and winter. Initially, nonspecific symptoms predominate, including fever, chills or frank shaking, headaches, myalgia (muscle pain), malaise (discomfort), and anorexia.
Seasonal Influenza Diagnosis
A diagnosis of influenza is made mostly on the basis of clinical presentation and epidemiological likelihood of infection. As influenza-like illness can be caused by many viruses, the gold standard laboratory tests used for influenza are viral culture and reverse transcription PCR (RT-PCR).
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Seasonal Influenza Treatment
Influenza occurs in outbreaks and epidemics worldwide, mainly during the winter season. Influenza is usually a self-limited infection; however, it is associated with increased morbidity and mortality in certain high-risk patient groups. Some treatments can help relieve common flu symptoms such as fever, aches, and cough and may shorten the time of flu symptoms.
Many people with uncomplicated influenza use over-the-counter medicines, get rest and take plenty of fluids to lessen their symptoms.
The FDA has approved several drugs for the treatment and prevention of influenza. Yearly vaccination is the primary means of preventing and controlling influenza. Antiviral drugs can reduce the time it takes for symptoms to improve. Some are also used in selected situations to reduce the chance of illness in people exposed to influenza virus.
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Seasonal Influenza Epidemiology
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Total Medical visits related to Seasonal Influenza, Total Hospitalized Cases of Seasonal Influenza, Type-specific Cases of Seasonal Influenza, and Influenza Vaccination Coverage in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2019 to 2032.
Key Findings
- In the assessment done by DelveInsight, the estimated total medical visits related to seasonal influenza in the 7MM were 11,235,325 in 2021.
- The highest total medical visits related to Seasonal Influenza were accounted by the US in 2021 (4,314,281 cases), which are expected to show a rise in the future.
- In the EU-5, in 2021, Italy had the highest medical visits related to seasonal influenza with 2,937,446 cases, followed by France with 1,977,533 cases in the same year. On the other hand, Spain had the lowest medical visits of seasonal influenza as 228,686 cases in 2021.
- In 2021, the total hospitalized cases of seasonal influenza was 173,227 in 7MM which are expected to increase by 2032.
- Type-specific cases of seasonal influenza were categorized into two types, Type A and Type B. The United States showed the highest cases of Type A compared to other 7MM countries. In 2021, the US, alone accounts for approximately 60% of total cases of Type A influenza.
- In 2021, the total vaccinated population estimated to be 366,474,828 in the 7MM. Highest vaccinated population was seen in the US.
- In Japan, 8,105 medical visits related to seasonal influenza were estimated in 2021, which are expected to decline during the forecasted period (2022-2032).
- During the peak year of COVID-19 pandemic, a steep decline in the cases of seasonal influenza was recorded throughout the 7MM. These cases are anticipated to rise again during the forecasted period (2022-2032).
Seasonal Influenza Epidemiology
The epidemiology segment also provides the Seasonal Influenza epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
Seasonal Influenza Drug Chapters
The drug chapter segment of the Seasonal Influenza report encloses the detailed analysis of Seasonal Influenza drugs, mid-phase, and late-stage pipeline drugs. It also helps to understand the Seasonal Influenza clinical trial details, expressive pharmacological action, agreements and collaborations, approval, and patent details of each included drug and the latest news and press releases.
Seasonal Influenza Marketed Therapies
XOFLUZA (baloxavir marboxil): Genentech/Roche
XOFLUZA is a first-in-class, single-dose oral medicine with an innovative proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies.
Seasonal Influenza Marketed Vaccine
FLUZONE QUADRIVALENT /VAXIGRIP TETRA: Sanofi
FLUZONE QUADRIVALENT is a quadrivalent inactivated influenza vaccine produced in the US, containing two Type A antigens and two Type B antigens to provide increased protection against more circulating strains of influenza viruses.
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Seasonal Influenza Emerging Therapies
SAB-176: SAb Biotherapeutics, Inc.
SAB-176 is a multivalent, broadly neutralizing fully human polyclonal antibody therapeutic candidate developed by SAb Biotherapeutics that leverages the human biological immune response in developing the treatment of hospitalized patients with severe seasonal influenza.
Seasonal Influenza Emerging Vaccines
mRNA-1010: ModernaTX, Inc.
mRNA-1010 is Moderna's first seasonal influenza mRNA vaccine candidate to enter the clinic. The mRNA-1010 is a quadrivalent vaccine candidate that encodes for hemagglutinin glycoproteins of the four influenza strains recommended by the WHO for the prevention of influenza, including influenza A/H1N1, A/H3N2, and Influenza B/Yamagata- and B/Victoria-lineages.is Moderna's first seasonal influenza mRNA vaccine candidate to enter the clinic.
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Seasonal Influenza Market Outlook
Seasonal Influenza spreads through respiratory droplets and is very contagious, and most people can receive at-home care for the flu. Symptom relief may be achieved by combining lifestyle changes with over-the-counter medications. Patients not from a high-risk group can be managed with symptomatic treatment whereas, patients with severe or progressive clinical illness associated with suspected or confirmed influenza virus infection (i.e., clinical syndromes of pneumonia, sepsis, or exacerbation of chronic underlying diseases) can be treated with the antiviral drug. Prophylactic treatment is part of the treatment for influenza.
Antiviral medicines play a vital role in controlling influenza by treating the patient's infection and helping to prevent severe illnesses resulting from flu, including bacterial pneumonia. Several antiviral drugs are available to target the influenza virus, such as oseltamivir (TAMIFLU), zanamivir (RELENZA), peramivir (RAPIVAB), and some others.
The best way to reduce the risk of seasonal influenza and its potentially serious complications is to get vaccinated every year. Vaccination of people at higher risk of developing serious flu complications is essential to decrease their risk of severe flu illness.
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Key Findings
- The therapeutic market size of Seasonal Influenza in the 7MM was USD 6,646 million in 2021.
- Among all seven major markets, the US consistently captured the highest market with USD 3,999 million in 2021, which might grow by 2032.
- Among the EU5 countries, Germany being the player captured total market share of USD 523 million followed by France, Italy, the UK and Spain in 2021.
- Among 7MM, Japan represented approximately 12% of the total market of seasonal flu in 2021, which is expected to increase by 2032.
- Several companies are trying their hand in the developmental pipeline of seasonal influenza to address some unmet needs and gain bundles of market opportunities. The pipeline projects are focused on the prevention and treatment of the flu.
- The entry of mid and late-phase potential molecules like mRNA-1010 (ModernaTX, Inc.), Quadrivalent VLP vaccine (Medicago), NanoFlu (Novavax), SAB-176 (SAb Biotherapeutics) and some others, covering a broad spectrum of seasonal influenza may bring revolution in the prevention and treatment by 2032.
The United States Market Outlook
This section provides the total Seasonal Influenza market size and market size by therapies in the United States.
EU-5 Market Outlook
The total Seasonal Influenza market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom are provided in this section.
Japan Market Outlook
The total Seasonal Influenza market size and market size by therapies in Japan are provided.
Seasonal Influenza Drugs Uptake
This section focuses on the rate of uptake of the potential drugs recently launched in the Seasonal Influenza or expected to get launched in the market during the study period 2019-2032. The analysis covers Seasonal Influenza market uptake by drugs; patient uptake by therapies; and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs based on market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Seasonal Influenza Development Activities
The report provides insights into different therapeutic candidates in the Early Phase, Phase II, and Phase III stages. It also analyzes key players involved in developing targeted therapeutics.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition, and merger, licensing, and patent details for Seasonal Influenza emerging therapies.
Reimbursement Scenario in Seasonal Influenza
Reimbursement is a crucial factor affecting the drug's market access. The NC Immunization Program/Vaccines for Children (NCIP/VFC) offers vaccines at no cost for eligible children through VFC-enrolled doctors. TRICARE program covers age-appropriate doses of vaccines, as recommended by CDC, and it regularly adds coverage for new vaccines based on CDC recommendations. The Medicare Part B payment allowance limits for seasonal influenza (flu) vaccines are 95% of the average wholesale price (AWP), as reflected in the published compendia.
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Competitive Intelligence Analysis
We perform competitive and market Intelligence analysis of the Seasonal Influenza market by using various competitive intelligence tools that include-SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability.
Scope of the Reports
- The report covers the descriptive overview of Seasonal Influenza, explaining its signs and symptoms, causes, classification, and currently available therapies.
- Comprehensive insight has been provided into the Seasonal Influenza epidemiology and treatment.
- Additionally, an all-inclusive account of both the current and emerging therapies for Seasonal Influenza is provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape.
- A detailed review of the Seasonal Influenza market; historical and forecasted is included in the report, covering the 7MM drug outreach.
- The report provides an edge while developing business strategies, by understanding trends shaping and driving the 7MM Seasonal Influenza market.
Report Highlights:
- The robust pipeline with novel MOA and oral ROA will positively drive the Seasonal Influenza market.
- The companies and academics are working to assess challenges and seek opportunities that could influence Seasonal Influenza R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition and underlying cause.
- Major players are involved in developing therapies for Seasonal influenza. The launch of emerging therapies will significantly impact the Seasonal Influenza market.
- Our in-depth analysis of the pipeline assets across different stages of development, different emerging trends, and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, and launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities.
Seasonal Influenza Report Insights
- Patient Population
- Therapeutic Approaches
- Seasonal Influenza Pipeline Analysis
- Seasonal Influenza Market Size and Trends
- Market Opportunities
- Impact of upcoming Therapies
Seasonal Influenza Report Key Strengths
- 11-Years Forecast
- 7MM Coverage
- Seasonal Influenza Epidemiology Segmentation
- Key Cross Competition
- Highly Analyzed Market
- Drugs Uptake
Seasonal Influenza Report Assessment
- Current Treatment Practices
- Unmet Needs
- Pipeline Product Profiles
- Market Attractiveness
- Market Drivers and Barriers
- SWOT analysis
Key Questions
Market Insights:
- What was the Seasonal Influenza market share (%) distribution in 2019 and how it would look like in 2032?
- What would be the Seasonal Influenza total market size as well as market size by therapies across the 7MM during the forecast period (2022-2032)?
- What are the key findings pertaining to the market across the 7MM and which country will have the largest Seasonal Influenza market size during the forecast period (2022-2032)?
- At what CAGR, the Seasonal Influenza market is expected to grow at the 7MM level during the forecast period (2022-2032)?
- What would be the Seasonal Influenza market outlook across the 7MM during the forecast period (2022-2032)?
- What would be the Seasonal Influenza market growth till 2032 and what will be the resultant market size in the year 2032?
- How would the market drivers, barriers, and future opportunities affect the market dynamics and subsequent analysis of the associated trends?
Epidemiology Insights:
- What is the disease risk, burden, and unmet needs of Seasonal Influenza?
- What is the historical Seasonal Influenza patient population in the United States, EU5 (Germany, France, Italy, Spain, and the UK), and Japan?
- What would be the forecasted patient population of Seasonal Influenza at the 7MM level?
- What will be the growth opportunities across the 7MM with respect to the patient population pertaining to Seasonal Influenza?
- Out of the above-mentioned countries, which country would have the highest cases of Seasonal Influenza during the forecast period (2022-2032)?
- At what CAGR the population is expected to grow across the 7MM during the forecast period (2022-2032)?
Current Treatment Scenario, Marketed Drugs, and Emerging Therapies:
- What are the current options for the treatment of Seasonal Influenza along with the approved therapy?
- What are the current treatment guidelines for the treatment of Seasonal Influenza in the US, Europe, And Japan?
- What are the Seasonal Influenza marketed drugs and their MOA, regulatory milestones, product development activities, advantages, disadvantages, safety, and efficacy, etc.?
- How many companies are developing therapies for the treatment of Seasonal Influenza?
- How many emerging therapies are in the mid-stage and late stages of development for the treatment of Seasonal Influenza?
- What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Seasonal Influenza therapies?
- What are the recent therapies, targets, mechanisms of action and technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Seasonal Influenza and their status?
- What are the key designations that have been granted for the emerging therapies for Seasonal Influenza?
- What are the 7MM historical and forecasted market of Seasonal Influenza?
Reasons to buy:
- The report will help in developing business strategies by understanding trends shaping and driving the Seasonal Influenza.
- To understand the future market competition in the Seasonal Influenza market and an Insightful review of the key market drivers and barriers.
- Organize sales and marketing efforts by identifying the best opportunities for Seasonal Influenza in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
- Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors.
- Organize sales and marketing efforts by identifying the best opportunities for the Seasonal Influenza market.
- To understand the future market competition in the Seasonal Influenza market.