PUBLISHER: Coherent Market Insights | PRODUCT CODE: 1392044
PUBLISHER: Coherent Market Insights | PRODUCT CODE: 1392044
The Global Macrophage Marker Market was valued at US$ 256.2 million in 2023 and is projected to reach US$ 398.2 million by 2030, at a CAGR of 6.5% from 2023 to 2030.
Report Coverage | Report Details | ||
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Base Year: | 2022 | Market Size in 2023: | US$ 256.2 Mn |
Historical Data for: | 2018 to 2021 | Forecast Period: | 2023 - 2030 |
Forecast Period 2023 to 2030 CAGR: | 6.50% | 2030 Value Projection: | US$ 398.2 Mn |
Macrophages are white blood cells that play a key role in immunity and homeostasis. They act as first responders, ingesting foreign materials, microbes, and debris. Due to their importance, it is essential to characterize and study macrophage biology. Macrophage markers allow researchers to identify, isolate, track, and target these cells. There are two main types of macrophage markers. The first are cell surface markers, which are proteins expressed on the outer membrane of macrophages that can be detected using fluorescence-activated cell sorting or immunohistochemistry techniques. Common macrophage cell surface markers include CD68, CD14, CD163, and CD206. The second type are intracellular markers, which are proteins located inside macrophage cells.
Intracellular markers provide information about macrophage activation and function but require fixed and permeabilized cells. Cell surface markers have the advantage of allowing live cell analysis, isolation, and potentially targeting of macrophages. However, no single marker is specific enough to uniquely identify macrophages, and marker expression can change depending on activation state and tissue environment. Ideally, a combination of several markers is used to accurately characterize macrophage phenotypes and populations. The global market offers a wide variety of monoclonal antibodies against macrophage markers, aiding fundamental and applied research seeking new treatment strategies across medical conditions.
Increasing research in immunology, the growing prevalence of chronic diseases, technological advancements, and personalized medicine approaches are major factors expected to drive growth of the global macrophage marker market during the forecast period.
For instance, in June 2022, according to a report published by the National Center for Biotechnology information, approximately 21% of the elderly in India reportedly have at least one chronic disease.
While, in December 2020, according to a report published by the Union for International Cancer Control, globally, 1 in 5 people develop cancer during their lifetime, and 1 in 8 men and 1 in 11 women die from the disease.
However, the complexity of macrophage heterogeneity, a lack of specificity and sensitivity, and the limited availability of validated antibodies are expected to hamper growth of the global macrophage marker market over the forecast period.
Global Macrophage Marker Market Detailed Segmentation: