PUBLISHER: Coherent Market Insights | PRODUCT CODE: 1290603
PUBLISHER: Coherent Market Insights | PRODUCT CODE: 1290603
Surface Plasmon Resonance (SPR) is an optical technique used for real time, label free detection of molecular interactions between mobile molecules with molecule immobilized on a thin metal film. Surface plasmon systems are used in pharmaceutical industry for drug discovery, and quality control. The identification of the molecule is based upon the interaction specificity of the molecule attached on the surface. Surface plasmon resonance helps in determining the specificity, affinity, and kinetic properties of the molecule. This generates electron charge density waves called plasmons, reducing the intensity of reflected light at a specific angle known as the resonance angle, in proportion to the mass on a sensor surface. Biacore Surface Plasmon Resonance (SPR) systems are used primarily in pharmaceutical development, quality control, and basic life science research. Based on the physical mechanism and the peculiar properties of Surface Plasmon Resonance (SPR), emonstrate the major applications of SPPs, such as waveguides, sources, near-field optics, surface-enhanced Raman spectroscopy, data storage, solar cells, chemical sensors and biosensors.
Surface plasmon resonance technology is useful to monitor biomolecular binding interactions in real-time. It has several advantages over other techniques such as real-time monitoring, label-free detection, small sample size requirement, reusable sensor chips, use of complex samples, and shorter experimental runs. SPR enables the highly sensitive and label-free assessment of affinity, kinetics and thermodynamics for ligand target interactions. In the drug discovery process, appropriate use of biophysical instrumentation can help advance hits earlier and more efficiently.
Increasing adoption of inorganic growth strategies, such as increasing product launch of surface plasmon resonance in the field of drug discovery by key players in the market to expand their product portfolio, is expected to drive the market growth over the forecast period. For instance, in Biosensing Instrument Inc. is a life science company that designs award winning label-free molecular interaction instruments using the SPR technology has introduced the Surface plasmon resonance Microscopy system, which is available commercially for interactions research. This move has redefined the use of surface plasmon resonance technology nad provides kinetic studies with single instrument.
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