PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1575044
PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1575044
Human Liver Model Market size was valued at USD 1,201.32 Million in 2023, expanding at a CAGR of 10.99% from 2024 to 2032.
The human liver model is an experimental or computational representation of the human liver used for research and medical purposes. These models are designed to study liver function, disease, and drug interactions in a controlled environment. There are several types of human liver models, each serving distinct purposes.
Human Liver Model Market- Market Dynamics
Growth in drug discovery & development, 3D cell culture technology and prevalence of liver disorders is expected to propel market demand
Liver models are essential in drug discovery for testing drug metabolism, toxicity, and efficacy, as the liver is a primary site of drug metabolism. The pharmaceutical industry's growing investment in drug research and development, including precision medicine and biologics, has increased the demand for human liver models, which in turn is boosting market growth. Technological advancements in 3D cell culture, microfluidic systems, and organ-on-a-chip platforms have enabled the creation of more physiologically relevant liver models. These innovations offer better simulation of liver function and response, encouraging adoption by researchers.
The rising incidence of liver diseases such as hepatitis, non-alcoholic fatty liver disease (NAFLD), cirrhosis, and liver cancer has led to an increased need for advanced research tools and therapeutic solutions. This, in turn, drives the demand for accurate liver models for studying disease mechanisms and developing new treatments. Regulatory bodies and the scientific community are pushing for alternative testing methods to reduce animal testing. Human liver models, including liver organoids and liver-on-a-chip systems, provide a viable in vitro alternative, driving market growth. Governments and research institutions worldwide are increasingly funding projects aimed at improving organ modeling technologies, including liver models. This funding accelerates the development and commercialization of innovative liver models.
Human Liver Model Market- Key Insights
As per the analysis shared by our research analyst, the global market is estimated to grow annually at a CAGR of around 10.99% over the forecast period (2024-2032)
Based on Product Type segmentation, the 2D models segment was predicted to show maximum market share in the year 2023, owing to its high applications in pharmaceutical research & drug development.
Based on Application segmentation, ADME studies segment was the leading Application segment in 2023, due to the accelerating demand for advanced liver models.
Based on End User segmentation, biopharmaceutical companies' segment was the leading End User segment in 2023, due to the growing need for liver models in assessing drug-drug interactions, drug metabolism, etc.
On the basis of region, North America was the leading revenue generator in 2023, due to the supportive regulatory environment.
Global Human Liver Model Market is segmented on the basis of Product Type, Application, End User, and Region.
The market is divided into two categories based on Product Type: 2D models and 3D models. The 2D models segment dominates the market. Increasing application in disease modelling and in vivo conditions is mainly fueling segment growth.
The market is divided into four categories based on Application: ADME studies, toxicology testing, disease modelling and others. The ADME studies segment dominates the market. The toxicology testing segment is estimated to expand at the fastest CAGR over the forecast period with rising demand from in-vitro testing.
The market is divided into three categories based on End User: biopharmaceutical companies. CROs, and academic research. The biopharmaceutical companies segment dominates the market and is expected to maintain its high dominance during the forecast period. Liver models help biopharma companies to assess accuracy of their drug development processes in rapid time.
Human Liver Model Market- Geographical Insights
Geographically, this market is widespread in the regions of North America, Latin America, Europe, Asia Pacific, and the Middle East and Africa. North America holds a significant share of the global human liver model market due to the presence of major pharmaceutical and biotechnology companies, a high number of research institutions, and advanced healthcare infrastructure. The Asia-Pacific region is experiencing rapid growth in the human liver model market, driven by increasing investment in biotechnology, expanding pharmaceutical industries, and rising prevalence of liver diseases. Growing pharmaceutical and clinical research outsourcing to countries like China and India, increasing government funding for biomedical research.
The competitive landscape of the human liver model market is shaped by a variety of companies, including established players, innovative startups, and research organizations. These companies are focusing on developing advanced liver models to cater to the growing demand for drug testing, disease modeling, etc. Companies are focusing on developing more physiologically relevant liver models, such as 3D bio printed liver tissues and microfluidic liver-on-chip devices. Key players are collaborating with pharmaceutical companies and academic institutions to validate and commercialize their liver models.
In April 2024, CN Bio Innovations received USD 21 million in Series-B funding to develop its organ-on-a-chip (OOC) technologies.
In 2022, InSphero AG introduced advanced models for NASH and liver fibrosis research, enabling better in vitro modeling of complex liver diseases.