PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1515603
PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1515603
Cancer Cachexia Market size was valued at USD 3,228.32 Million in 2023, expanding at a CAGR of 5.90% from 2024 to 2032.
Cancer cachexia presents as a multifaceted metabolic syndrome frequently observed in patients with advanced stages of malignancy. Characterized by involuntary weight loss, skeletal muscle wasting, fatigue, and anorexia, this syndrome transcends the limitations of inadequate dietary intake. Underlying mechanisms encompass systemic inflammation, metabolic aberrations, and the host's response to tumor-derived factors. Despite advancements in oncological therapies, cancer cachexia remains a formidable challenge, significantly impacting both the treatment outcomes and quality of life for affected individuals.
Cancer Cachexia Market- Market Dynamics
Rising cancer burden to propel market demand
The global cancer burden is rising, necessitating the modification of cancer therapies according to national and regional priorities. According to the (IARC) International Agency for Research on Cancer in December 2020, 1 in 5 people globally will develop cancer during their lifetime, with 1 in 11 women and 1 in 8 men dying from the disease. Data from the WHO, published in February 2022, indicates that approximately 400,000 children develop cancer annually, with the most common types varying by country. For instance, cervical cancer is the most prevalent in 23 countries. The increasing global cancer burden also raises the prevalence of cancer cachexia, characterized by negative protein and energy balance, systemic inflammation, and involuntary loss of lean body mass. The growing prevalence of cancer cachexia, and cancer along with increased investment in R&D for novel cancer cachexia treatments, are major factors driving market growth.
Cancer Cachexia Market- Key Insights
As per the analysis shared by our research analyst, the global market is estimated to grow annually at a CAGR of around 5.90% over the forecast period (2024-2032)
Based on Therapeutics segmentation, progestogens were predicted to show maximum market share in the year 2023
Based on the mechanism of action segmentation, appetite stimulators were the leading type in 2023
On the basis of region, North America was the leading revenue generator in 2023
The Global Cancer Cachexia Market is broadly segmented on the basis of Therapeutics, Mechanism of Action, Application, and Region.
The market is divided into four categories based on Therapeutics: progestogens, corticosteroids, combination therapies, and others. The progestogens segment held a dominant market share in 2023, due to their lower cost and high efficiency in treating cancer cachexia.
The market is broadly divided into two categories based on mechanism of action: Appetite Stimulators and Weight Loss Stabilizers. By mechanism of action, appetite stimulators are expected to dominate and grow significantly in the cancer cachexia market. Cancer patients often experience sort of appetite loss and unintended weight loss, which are linked to decreased performance status, reduced response and tolerance to treatment, decreased survival, and diminished quality of life. Therefore, the use of appetite stimulants is increasingly considered for patients with reduced appetite. The rising prevalence of cancer cachexia is a major factor driving the market's growth.
Cancer Cachexia Market- Geographical Insights
From a geographical perspective, this market extends across Europe, North America, Latin America, Asia Pacific, and the Middle East and Africa. These regions are further segmented based on the participating nations. North America is expected to lead the market, driven by the high burden of cancer and cancer cachexia, the presence of numerous drug manufacturers, and advancements in cancer patient care. According to GLOBOCAN 2020 estimates, Mexico reported around 195,499 new cancer cases. Additionally, the American Cancer Society projected approximately 1.9 million new cancer cases would be diagnosed in the United States in 2022.
The cancer cachexia market is consolidated, with only a few major companies operating globally and regionally. These key players are primarily focused on R&D to develop highly effective novel drugs for treating cancer cachexia, resulting in a growing pipeline of therapeutics awaiting approval and commercial launch. As of October 2022, clinicaltrials.gov reported 150 studies either conducted or ongoing to develop drugs for cancer cachexia. For instance, in December 2020, the University of Copenhagen, in collaboration with Zealand University Hospital, initiated a study to monitor the effect of the medical cannabidiol on the lean body mass (cachexia) in patients receiving Oxaliplatin- or Paclitaxel-based chemotherapy.
In January 2021, Helsinn Group and Ono Pharmaceutical Co. Ltd received approval in Japan to manufacture and market Adlumiz, a ghrelin receptor agonist for treating cancer cachexia in the patients with non-small cell lung cancer, gastric cancer, pancreatic cancer, or colorectal cancer. Therefore, increasing research and development activities in the field are expected to drive market growth.
GLOBAL CANCER CACHEXIA MARKET KEY PLAYERS- DETAILED COMPETITIVE INSIGHT
Aeterna Zentaris
Aphios Corporation
Bristol-Myers Squibb Company
Pfizer Inc.
Helsinn Group
Merck KGaA
Artelo Biosciences Inc.
NGM Biopharmaceuticals
Aveo Oncology
Aavogen Inc.
Green Cross Wellbeing Corporation
Cannabics Pharmaceuticals Inc.
TCI Peptide Therapeutics
Fresenius Kabi
Tetra Bio-Pharma
Actimed Therapeutics
Others