PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1364703
PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1364703
T-Cell Therapy Market size was valued at USD 2,708.6 Million in 2022, expanding at a CAGR of 34.9% from 2023 to 2030.
T-cell therapy is a form of immunotherapy in which T-cells, a type of white blood cell, are used to treat specific disorders, most notably cancer. There are two main types of T-cell transfer therapy tumor-infiltrating lymphocytes (or TIL) therapy and CAR T-cell therapy. T-cell transfer therapy was initially investigated for the treatment of metastatic melanoma since melanomas frequently cause a robust immune response and have a high number of TILs. TIL treatment has been shown to be successful in some cases of melanoma and has achieved encouraging results in other cancers such as cervical squamous cell carcinoma and cholangiocarcinoma. However, T-cell therapy is a key advancement in cancer treatment. Conversely, like many medicines, it comes with both enormous promise and significant challenges. There is continuing research to increase the efficacy, safety, and accessibility of these medicines.
The rising focus on Developing new therapies for the treatment of diseases is expected to drive the growth of the T-cell therapy market.
As the global prevalence of diseases, particularly cancer, rises, there is an urgent requirement for more effective and tailored therapies. According to the National Cancer Institute, in 2023, roughly 2.0 million people will be diagnosed with cancer in the United States. An estimated 297,790 women and 2,800 men will be diagnosed with breast cancer, which makes it the most common cancer diagnosis. T-cell treatments are emerging as a viable treatment option, particularly for individuals suffering from resistant or recurrent diseases. Given the potential of T-cell treatments, enormous investment has been made in research and development. Furthermore, advancing research on novel biotherapies and increasing the supply and safety of biologics are the factors that are expected to provide growth opportunities for the T-cell therapy market. However, severe life-threatening toxicities, modest anti-tumor activity, antigen escape, restricted trafficking, and limited tumor infiltration are the factors that restrict the growth of the market.
The Global T-Cell Therapy Market is segmented on the basis of Therapy Type, Indication, and Region.
The market is divided into three categories based on Therapy type: CAR T-cell Therapy, Cell Receptor (TCR)-based, and Tumor Infiltrating Lymphocytes (TIL)-based. CAR T-cell Therapy segment is expected to dominate the market growth. CAR-T therapy is a type of T-cell therapy in which T-cells are genetically engineered to express a receptor (the CAR) that can specifically target cancer cells.
The market is divided into two categories based on Indication: Hematologic Malignancies, Solid Tumors, and Others. Hematologic Malignancies dominate the market growth. CAR-T-cell immunotherapy is widely recognized as an important treatment option for patients suffering from hematological malignancies such as acute lymphoblastic leukemia (ALL), multiple myeloma (MM), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), Hodgkin lymphoma (HL), and non-Hodgkin lymphoma (NHL).
Geographically, this market is widespread into the regions of North America, Latin America, Europe, Asia Pacific, and the Middle East and Africa. These regions are further divided as per the nations bringing business. North America is expected to dominate the growth of the market, due to the increasing number of pharmaceutical companies focusing on developing adoptive therapies, North America, particularly the United States, is host to a myriad of biotech startups, prestigious research institutions, and some of the world's largest pharmaceutical companies. These organizations actively invest in and push the margins of novel therapeutics, such as adoptive T-cell therapy. For example, Fate Therapeutics, Inc, a clinical-stage biopharmaceutical company dedicated to the development of programmed cellular immunotherapies for patients with cancer, presented preclinical data of several novel strategies designed to enable the administration of off-the-shelf cell-based cancer immunotherapies without conditioning chemotherapy at the 64th American Society of Hematology (ASH) Annual Meeting and Exposition.
The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet need, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. Furthermore, Europe and Asia Pacific are expected to propel significant growth in T-cell therapy Market, due to the Growing Product Approvals Associated with T-cell therapies like Chimeric antigen receptor (CAR)-T cell therapy and T Cell Receptor (TCR)-based and Tumor Infiltrating Lymphocytes (TIL)-based.
Several new market players are driving innovation in the field of T-cell therapy. Some are concentrating on next-generation CAR-T therapy, while others are investigating alternate cell types, safer designs, or cost-cutting strategies. Also, the robust development of new CAR-T therapies is characterized by the active use of intellectual property rights by firms, as well as substantial R&D investments. Manufacturers exhibit CAR-T technologies' patent and clinical landscape, covering the current clinical trial environment, cutting-edge CAR-related inventions, the main actors, and how they interact with one another to generate new technologies. Furthermore, T-cell treatments were initially more focused in regions such as North America and parts of Europe. Regulatory approvals in Asia-Pacific, Latin America, and the Middle East can open up large new markets, raising demand as corporations expand their reach.
In October 2019, Merck, a leading science and technology company, nowadays announced it had acquired FloDesign Sonics, of Wilbraham, Massachusetts, USA, developer of a unique acoustic cell processing platform for the industrialization of cell and gene therapy manufacturing. Financial details were not disclosed.
The scope of this report covers the market by its major segments, which include as follows: