Hydrophobic Interaction Chromatography Market By Product and Service, By Sample type, By Application, By End user : Global Opportunity Analysis and Industry Forecast, 2024-2033

Description

Hydrophobic Interaction Chromatography Market

The hydrophobic interaction chromatography market was valued at $461.89 million in 2023 and is estimated to reach $952.93 million by 2033, exhibiting a CAGR of 7.5% from 2024 to 2033.

Hydrophobic interaction chromatography (HIC) is a biomolecular separation technique that differentiates proteins and other biomolecules depending on their hydrophobicity. The working principle of HIC involves the reversible binding of proteins to hydrophobic groups on a stationary phase, under the influence of ionic strength of a mobile phase. The technique finds application in antibody isolation, protein purification, and separation of hydrophobic compounds in biotechnological & pharmaceutical industries.

The expanding biopharmaceutical industry across the globe is a key driver of the hydrophobic interaction chromatography market as it utilizes HIC in the development process of medicines and vaccines. In addition, rise in investments in the biotechnology & research sector by governments and private organizations has propelled the growth of the market. A notable trend acquiring traction in the hydrophobic interaction chromatography market is the use of HIC in the food and dietary supplement industries. They utilize HIC to improve taste and nutritional value by the separation & purification of proteins and peptides.

However, the inability of the technique scale-up and cater to extensive purification requirements hampers the development of the market. Furthermore, HIC is a relatively time-consuming technique and faces stringent competition from alternatives such as affinity & ion-exchange chromatography. This reduces the utility of HIC and restrains the market growth significantly. On the contrary, increase in the number of biotech start-ups and surge in investments in them is expected to present lucrative growth opportunities for the hydrophobic interaction chromatography market. McKinsey data states that investments by venture capital firms increased from 2,200 biotech start-ups globally in 2,016 to 3,100 in 2021. Moreover, the start-ups collected more than $34 billion globally in 2021, which was more than double the 2020 total of $16 billion. This upsurge in investments is anticipated to increase protein- and molecular biology-related research, fueling the requirement for advanced HIC equipment.

Segment Review

The hydrophobic interaction chromatography market is segmented into product & service, sample type, application, end user, and region. By product & service, the market is bifurcated into product and service. The product segment is further categorized into resin, buffer, column, and others. The resin segment is further bifurcated into beads and others. The column segment is further divided into pre-packed columns and empty columns. The pre-packed column segment is further categorized into disposable and reusable. Depending on sample type, the market is segregated into monoclonal antibodies, vaccines, cell culture sample, plasma & serum sample, and others. As per application, it is classified into protein & antibody purification, vaccine development, drug discovery, and food & dietary supplement development. The protein & antibody purification segment is further categorized for resins into beads and others. According to end user, the market is categorized into pharmaceutical & biopharmaceutical companies, contract research organizations & contract manufacturing organizations, research & academic institutes, and others. Region wise, the market is analyzed across North America (U.S., Canada, and Mexico), Europe (Germany, France, the UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, India, Australia, South Korea, and rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and rest of LAMEA).

Key Findings

By product & service, the product segment dominated the market share in 2023.

Depending on sample type, the monoclonal antibodies segment held a high share of the market.

As per application, the protein & antibody purification segment accounted for the highest market share in 2023.

According to end user, the pharmaceutical & biopharmaceutical companies segment was the highest shareholder in 2023.

Region wise, North America was the highest revenue generator in 2023.

Competition Analysis

The major players operating in the global hydrophobic interaction chromatography market are Bio-Rad Laboratories, Inc., Sartorius AG, Thermo Fisher Scientific Inc., Tosoh Corporation, Danaher Corporation, Sepax Technologies, Inc., Agilent Technologies, Inc., Merck KGaA, Waters Corporation, and KNAUER Wissenschaftliche Gerate GmbH. These major players have adopted integration, product launch, contract, partnership, and expansion as their key strategies to expand their product portfolio.

Key Benefits for Stakeholders

This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the hydrophobic interaction chromatography market analysis from 2023 to 2033 to identify the prevailing hydrophobic interaction chromatography market opportunities.

The market research is offered along with information related to key drivers, restraints, and opportunities.

Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.

In-depth analysis of the hydrophobic interaction chromatography market segmentation assists to determine the prevailing market opportunities.

Major countries in each region are mapped according to their revenue contribution to the global market.

Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.

The report includes the analysis of the regional as well as global hydrophobic interaction chromatography market trends, key players, market segments, application areas, and market growth strategies.

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SWOT Analysis

Key Market Segments

By Product and Service

Product
- Type
- Resin

◦ Type

Buffer
Column

◦ Type

Others

Service

By Sample type

Monoclonal antibodies
Vaccines
Cell culture sample
Plasma and serum sample
Others

By Application

Protein and antibody purification
- Resins
- Beads
- Others
Vaccine development
Drug discovery
Food and dietary supplement development

By End user

Research and academic institutes
Others
Pharmaceutical and biopharmaceutical companies
Contract research organizations and contract manufacturing organizations

By Region

North America
- U.S.
- Canada
- Mexico
Europe
- Germany
- France
- UK
- Italy
- Spain
- Rest of Europe
Asia-Pacific
- Japan
- China
- India
- Australia
- South Korea
- Rest of Asia-Pacific
LAMEA
- Brazil
- South Africa,
- Saudi Arabia
- Rest of LAMEA

Key Market Players:

Sepax Technologies, Inc.
Tosoh Corporation
Agilent Technologies, Inc.
Thermo Fisher Scientific Inc.
Danaher Corporation
Merck KGaA
Geno Technology, Inc.
Waters Corporation
KNAUER Wissenschaftliche Gerate GmbH
Bio-Rad Laboratories, Inc.
Sartorius AG

Product Code: A325383

CHAPTER 1: INTRODUCTION

1.1. Report description
1.2. Key market segments
1.3. Key benefits to the stakeholders
1.4. Research methodology
- 1.4.1. Primary research
- 1.4.2. Secondary research
- 1.4.3. Analyst tools and models

CHAPTER 2: EXECUTIVE SUMMARY

2.1. CXO perspective

CHAPTER 3: MARKET OVERVIEW

3.1. Market definition and scope
3.2. Key findings
- 3.2.1. Top impacting factors
- 3.2.2. Top investment pockets
3.3. Porter's five forces analysis
- 3.3.1. Moderate intensity of rivalry
- 3.3.2. Moderate bargaining power of buyers
- 3.3.3. Moderate threat of new entrants
- 3.3.4. Moderate bargaining power of suppliers
- 3.3.5. Moderate threat of substitutes
3.4. Market dynamics
- 3.4.1. Drivers
  - 3.4.1.1. Increase in R&D expenditure in biopharmaceuticals
  - 3.4.1.2. Rise in demand for biologics and monoclonal antibodies (mAbs)
  - 3.4.1.3. Rise in adoption of biosimilars
- 3.4.2. Restraints
  - 3.4.2.1. Lack of a skilled workforce
  - 3.4.2.2. High initial investment and operating costs
- 3.4.3. Opportunities
  - 3.4.3.1. Growth opportunities in emerging markets
  - 3.4.3.2. Technological advancements in hydrophobic interaction chromatography (HIC)

CHAPTER 4: HYDROPHOBIC INTERACTION CHROMATOGRAPHY MARKET, BY PRODUCT AND SERVICE

4.1. Overview
- 4.1.1. Market size and forecast
4.2. Product
- 4.2.1. Key market trends, growth factors and opportunities
- 4.2.2. Market size and forecast, by region
- 4.2.3. Market share analysis by country
- 4.2.4. Product Hydrophobic Interaction Chromatography Market by Type
  - 4.2.4.1. Resin Hydrophobic Interaction Chromatography Market by Type
  - 4.2.4.2. Column Hydrophobic Interaction Chromatography Market by Type
  - 4.2.4.2.1. Pre packed Columns Hydrophobic Interaction Chromatography Market by Type
4.3. Service
- 4.3.1. Key market trends, growth factors and opportunities
- 4.3.2. Market size and forecast, by region
- 4.3.3. Market share analysis by country

CHAPTER 5: HYDROPHOBIC INTERACTION CHROMATOGRAPHY MARKET, BY SAMPLE TYPE

5.1. Overview
- 5.1.1. Market size and forecast
5.2. Monoclonal antibodies
- 5.2.1. Key market trends, growth factors and opportunities
- 5.2.2. Market size and forecast, by region
- 5.2.3. Market share analysis by country
5.3. Vaccines
- 5.3.1. Key market trends, growth factors and opportunities
- 5.3.2. Market size and forecast, by region
- 5.3.3. Market share analysis by country
5.4. Cell culture sample
- 5.4.1. Key market trends, growth factors and opportunities
- 5.4.2. Market size and forecast, by region
- 5.4.3. Market share analysis by country
5.5. Plasma and serum sample
- 5.5.1. Key market trends, growth factors and opportunities
- 5.5.2. Market size and forecast, by region
- 5.5.3. Market share analysis by country
5.6. Others
- 5.6.1. Key market trends, growth factors and opportunities
- 5.6.2. Market size and forecast, by region
- 5.6.3. Market share analysis by country

CHAPTER 6: HYDROPHOBIC INTERACTION CHROMATOGRAPHY MARKET, BY APPLICATION

6.1. Overview
- 6.1.1. Market size and forecast
6.2. Protein and antibody purification
- 6.2.1. Key market trends, growth factors and opportunities
- 6.2.2. Market size and forecast, by region
- 6.2.3. Market share analysis by country
- 6.2.4. Protein and antibody purification Hydrophobic Interaction Chromatography Market by Resins
6.3. Vaccine development
- 6.3.1. Key market trends, growth factors and opportunities
- 6.3.2. Market size and forecast, by region
- 6.3.3. Market share analysis by country
6.4. Drug discovery
- 6.4.1. Key market trends, growth factors and opportunities
- 6.4.2. Market size and forecast, by region
- 6.4.3. Market share analysis by country
6.5. Food and dietary supplement development
- 6.5.1. Key market trends, growth factors and opportunities
- 6.5.2. Market size and forecast, by region
- 6.5.3. Market share analysis by country

CHAPTER 7: HYDROPHOBIC INTERACTION CHROMATOGRAPHY MARKET, BY END USER

7.1. Overview
- 7.1.1. Market size and forecast
7.2. Pharmaceutical and biopharmaceutical companies
- 7.2.1. Key market trends, growth factors and opportunities
- 7.2.2. Market size and forecast, by region
- 7.2.3. Market share analysis by country
7.3. Contract research organizations and contract manufacturing organizations
- 7.3.1. Key market trends, growth factors and opportunities
- 7.3.2. Market size and forecast, by region
- 7.3.3. Market share analysis by country
7.4. Research and academic institutes
- 7.4.1. Key market trends, growth factors and opportunities
- 7.4.2. Market size and forecast, by region
- 7.4.3. Market share analysis by country
7.5. Others
- 7.5.1. Key market trends, growth factors and opportunities
- 7.5.2. Market size and forecast, by region
- 7.5.3. Market share analysis by country

CHAPTER 8: HYDROPHOBIC INTERACTION CHROMATOGRAPHY MARKET, BY REGION

8.1. Overview
- 8.1.1. Market size and forecast By Region
8.2. North America
- 8.2.1. Key market trends, growth factors and opportunities
- 8.2.2. Market size and forecast, by Product and Service
- 8.2.3. Market size and forecast, by Sample type
- 8.2.4. Market size and forecast, by Application
- 8.2.5. Market size and forecast, by End user
- 8.2.6. Market size and forecast, by country
  - 8.2.6.1. U.S.
  - 8.2.6.1.1. Market size and forecast, by Product and Service
  - 8.2.6.1.2. Market size and forecast, by Sample type
  - 8.2.6.1.3. Market size and forecast, by Application
  - 8.2.6.1.4. Market size and forecast, by End user
  - 8.2.6.2. Canada
  - 8.2.6.2.1. Market size and forecast, by Product and Service
  - 8.2.6.2.2. Market size and forecast, by Sample type
  - 8.2.6.2.3. Market size and forecast, by Application
  - 8.2.6.2.4. Market size and forecast, by End user
  - 8.2.6.3. Mexico
  - 8.2.6.3.1. Market size and forecast, by Product and Service
  - 8.2.6.3.2. Market size and forecast, by Sample type
  - 8.2.6.3.3. Market size and forecast, by Application
  - 8.2.6.3.4. Market size and forecast, by End user
8.3. Europe
- 8.3.1. Key market trends, growth factors and opportunities
- 8.3.2. Market size and forecast, by Product and Service
- 8.3.3. Market size and forecast, by Sample type
- 8.3.4. Market size and forecast, by Application
- 8.3.5. Market size and forecast, by End user
- 8.3.6. Market size and forecast, by country
  - 8.3.6.1. Germany
  - 8.3.6.1.1. Market size and forecast, by Product and Service
  - 8.3.6.1.2. Market size and forecast, by Sample type
  - 8.3.6.1.3. Market size and forecast, by Application
  - 8.3.6.1.4. Market size and forecast, by End user
  - 8.3.6.2. France
  - 8.3.6.2.1. Market size and forecast, by Product and Service
  - 8.3.6.2.2. Market size and forecast, by Sample type
  - 8.3.6.2.3. Market size and forecast, by Application
  - 8.3.6.2.4. Market size and forecast, by End user
  - 8.3.6.3. UK
  - 8.3.6.3.1. Market size and forecast, by Product and Service
  - 8.3.6.3.2. Market size and forecast, by Sample type
  - 8.3.6.3.3. Market size and forecast, by Application
  - 8.3.6.3.4. Market size and forecast, by End user
  - 8.3.6.4. Italy
  - 8.3.6.4.1. Market size and forecast, by Product and Service
  - 8.3.6.4.2. Market size and forecast, by Sample type
  - 8.3.6.4.3. Market size and forecast, by Application
  - 8.3.6.4.4. Market size and forecast, by End user
  - 8.3.6.5. Spain
  - 8.3.6.5.1. Market size and forecast, by Product and Service
  - 8.3.6.5.2. Market size and forecast, by Sample type
  - 8.3.6.5.3. Market size and forecast, by Application
  - 8.3.6.5.4. Market size and forecast, by End user
  - 8.3.6.6. Rest of Europe
  - 8.3.6.6.1. Market size and forecast, by Product and Service
  - 8.3.6.6.2. Market size and forecast, by Sample type
  - 8.3.6.6.3. Market size and forecast, by Application
  - 8.3.6.6.4. Market size and forecast, by End user
8.4. Asia-Pacific
- 8.4.1. Key market trends, growth factors and opportunities
- 8.4.2. Market size and forecast, by Product and Service
- 8.4.3. Market size and forecast, by Sample type
- 8.4.4. Market size and forecast, by Application
- 8.4.5. Market size and forecast, by End user
- 8.4.6. Market size and forecast, by country
  - 8.4.6.1. Japan
  - 8.4.6.1.1. Market size and forecast, by Product and Service
  - 8.4.6.1.2. Market size and forecast, by Sample type
  - 8.4.6.1.3. Market size and forecast, by Application
  - 8.4.6.1.4. Market size and forecast, by End user
  - 8.4.6.2. China
  - 8.4.6.2.1. Market size and forecast, by Product and Service
  - 8.4.6.2.2. Market size and forecast, by Sample type
  - 8.4.6.2.3. Market size and forecast, by Application
  - 8.4.6.2.4. Market size and forecast, by End user
  - 8.4.6.3. India
  - 8.4.6.3.1. Market size and forecast, by Product and Service
  - 8.4.6.3.2. Market size and forecast, by Sample type
  - 8.4.6.3.3. Market size and forecast, by Application
  - 8.4.6.3.4. Market size and forecast, by End user
  - 8.4.6.4. Australia
  - 8.4.6.4.1. Market size and forecast, by Product and Service
  - 8.4.6.4.2. Market size and forecast, by Sample type
  - 8.4.6.4.3. Market size and forecast, by Application
  - 8.4.6.4.4. Market size and forecast, by End user
  - 8.4.6.5. South Korea
  - 8.4.6.5.1. Market size and forecast, by Product and Service
  - 8.4.6.5.2. Market size and forecast, by Sample type
  - 8.4.6.5.3. Market size and forecast, by Application
  - 8.4.6.5.4. Market size and forecast, by End user
  - 8.4.6.6. Rest of Asia-Pacific
  - 8.4.6.6.1. Market size and forecast, by Product and Service
  - 8.4.6.6.2. Market size and forecast, by Sample type
  - 8.4.6.6.3. Market size and forecast, by Application
  - 8.4.6.6.4. Market size and forecast, by End user
8.5. LAMEA
- 8.5.1. Key market trends, growth factors and opportunities
- 8.5.2. Market size and forecast, by Product and Service
- 8.5.3. Market size and forecast, by Sample type
- 8.5.4. Market size and forecast, by Application
- 8.5.5. Market size and forecast, by End user
- 8.5.6. Market size and forecast, by country
  - 8.5.6.1. Brazil
  - 8.5.6.1.1. Market size and forecast, by Product and Service
  - 8.5.6.1.2. Market size and forecast, by Sample type
  - 8.5.6.1.3. Market size and forecast, by Application
  - 8.5.6.1.4. Market size and forecast, by End user
  - 8.5.6.2. South Africa,
  - 8.5.6.2.1. Market size and forecast, by Product and Service
  - 8.5.6.2.2. Market size and forecast, by Sample type
  - 8.5.6.2.3. Market size and forecast, by Application
  - 8.5.6.2.4. Market size and forecast, by End user
  - 8.5.6.3. Saudi Arabia
  - 8.5.6.3.1. Market size and forecast, by Product and Service
  - 8.5.6.3.2. Market size and forecast, by Sample type
  - 8.5.6.3.3. Market size and forecast, by Application
  - 8.5.6.3.4. Market size and forecast, by End user
  - 8.5.6.4. Rest of LAMEA
  - 8.5.6.4.1. Market size and forecast, by Product and Service
  - 8.5.6.4.2. Market size and forecast, by Sample type
  - 8.5.6.4.3. Market size and forecast, by Application
  - 8.5.6.4.4. Market size and forecast, by End user

CHAPTER 9: COMPETITIVE LANDSCAPE

9.1. Introduction
9.2. Top winning strategies
9.3. Product mapping of top 10 player
9.4. Competitive dashboard
9.5. Competitive heatmap
9.6. Top player positioning, 2023

CHAPTER 10: COMPANY PROFILES

10.1. Bio-Rad Laboratories, Inc.
- 10.1.1. Company overview
- 10.1.2. Key executives
- 10.1.3. Company snapshot
- 10.1.4. Operating business segments
- 10.1.5. Product portfolio
- 10.1.6. Business performance
10.2. Sartorius AG
- 10.2.1. Company overview
- 10.2.2. Key executives
- 10.2.3. Company snapshot
- 10.2.4. Operating business segments
- 10.2.5. Product portfolio
- 10.2.6. Business performance
- 10.2.7. Key strategic moves and developments
10.3. Thermo Fisher Scientific Inc.
- 10.3.1. Company overview
- 10.3.2. Key executives
- 10.3.3. Company snapshot
- 10.3.4. Operating business segments
- 10.3.5. Product portfolio
- 10.3.6. Business performance
- 10.3.7. Key strategic moves and developments
10.4. Tosoh Corporation
- 10.4.1. Company overview
- 10.4.2. Key executives
- 10.4.3. Company snapshot
- 10.4.4. Operating business segments
- 10.4.5. Product portfolio
- 10.4.6. Key strategic moves and developments
10.5. Geno Technology, Inc.
- 10.5.1. Company overview
- 10.5.2. Key executives
- 10.5.3. Company snapshot
- 10.5.4. Operating business segments
- 10.5.5. Product portfolio
10.6. Danaher Corporation
- 10.6.1. Company overview
- 10.6.2. Key executives
- 10.6.3. Company snapshot
- 10.6.4. Operating business segments
- 10.6.5. Product portfolio
- 10.6.6. Business performance
- 10.6.7. Key strategic moves and developments
10.7. Sepax Technologies, Inc.
- 10.7.1. Company overview
- 10.7.2. Key executives
- 10.7.3. Company snapshot
- 10.7.4. Operating business segments
- 10.7.5. Product portfolio
10.8. Agilent Technologies, Inc.
- 10.8.1. Company overview
- 10.8.2. Key executives
- 10.8.3. Company snapshot
- 10.8.4. Operating business segments
- 10.8.5. Product portfolio
- 10.8.6. Business performance
10.9. Merck KGaA
- 10.9.1. Company overview
- 10.9.2. Key executives
- 10.9.3. Company snapshot
- 10.9.4. Operating business segments
- 10.9.5. Product portfolio
- 10.9.6. Business performance
- 10.9.7. Key strategic moves and developments
10.10. Waters Corporation
- 10.10.1. Company overview
- 10.10.2. Key executives
- 10.10.3. Company snapshot
- 10.10.4. Operating business segments
- 10.10.5. Product portfolio
- 10.10.6. Business performance
- 10.10.7. Key strategic moves and developments
10.11. KNAUER Wissenschaftliche Gerate GmbH
- 10.11.1. Company overview
- 10.11.2. Key executives
- 10.11.3. Company snapshot
- 10.11.4. Operating business segments
- 10.11.5. Product portfolio