This report provides a comprehensive analysis of the current and future landscape of multiple sclerosis (MS) therapies, focusing on the decline of oral disease-modifying therapies (DMTs) and the rise of higher-efficacy treatments. It examines the market dynamics of key therapies like Zeposia, Mavenclad, and Tysabri, and explores the potential of emerging treatments such as masitinib and tolebrutinib.
Key questions answered:
- 1. What events are impacting the uptake of oral DMTs?
- 2. How are therapies perceived by the medical community in terms of efficacy, tolerability, and ease of administration?
- 3. Which recently completed or ongoing clinical trials have the greatest potential to affect prescribing trends?
- 4. What will DMTs need to show to become the treatment of choice in specific therapy lines?
- 5. How will the use of each current and pipeline DMT change in the future in terms of line of therapy and preference?
- 6. What will pipeline products need to show in terms of efficacy and tolerability to compete with current therapies?
- 7. Which pipeline products are the most promising, and how will they impact current market players?
- 8. How will the treatment landscape for MS evolve in the future for each patient segment and line of therapy?
Key brands covered in this report:
- Mavenclad (cladribine)
- Ocrevus (ocrelizumab)
- masitinib
- Gilenya (fingolimod)
- Mayzent (siponimod)
- Kesimpta (ofatumumab)
- Tecfidera (dimethyl fumarate)
- Zeposia (ozanimod)
- Ponvory (ponesimod)
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- tolebrutinib
- Vumerity (diroximel fumarate)
- Tysabri (natalizumab)
- Briumvi (ublituximab)
- fenebrutinib
- remibrutinib
- Aubagio (teriflunomide)
- vidofludimus calcium
- frexalimab
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Companies:
- Novartis
- Roche
- Sanofi
- AB Science
- Bristol Myers Squibb
- Biogen
- Neuraxpharm
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- TG Therapeutics
- Vanda
- Merck Group
- Immunic
- ImmuNext
- Juvise Pharmaceuticals
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